Better substrates for bacterial transglycosylases XY Ye, MC Lo, L Brunner, D Walker, D Kahne, S Walker Journal of the American Chemical Society 123 (13), 3155-3156, 2001 | 190 | 2001 |
Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides HC Losey, J Jiang, JB Biggins, M Oberthür, XY Ye, SD Dong, D Kahne, ... Chemistry & biology 9 (12), 1305-1314, 2002 | 175 | 2002 |
Ramoplanin inhibits bacterial transglycosylases by binding as a dimer to lipid II Y Hu, JS Helm, L Chen, XY Ye, S Walker Journal of the american chemical society 125 (29), 8736-8737, 2003 | 113 | 2003 |
Enantioselective total synthesis of (−)-triptolide,(−)-triptonide,(+)-triptophenolide, and (+)-triptoquinonide D Yang, XY Ye, M Xu The Journal of Organic Chemistry 65 (7), 2208-2217, 2000 | 108 | 2000 |
Intrinsic Lipid Preferences and Kinetic Mechanism of Escherichia coli MurG L Chen, H Men, S Ha, XY Ye, L Brunner, Y Hu, S Walker Biochemistry 41 (21), 6824-6833, 2002 | 96 | 2002 |
Lanthanide triflates catalyze Mn (III)-based oxidative radical cyclization reactions. Enantioselective synthesis of (-)-triptolide,(-)-triptonide, and (+)-triptophenolide D Yang, XY Ye, S Gu, M Xu Journal of the American Chemical Society 121 (23), 5579-5580, 1999 | 92 | 1999 |
Investigation of Mn (III)-based oxidative free radical cyclization reactions toward the synthesis of triptolide: The effects of lanthanide triflates and substituents on … D Yang, XY Ye, M Xu, KW Pang, KK Cheung Journal of the American Chemical Society 122 (8), 1658-1663, 2000 | 63 | 2000 |
Selective Tyk2 inhibitors as potential therapeutic agents: a patent review (2015–2018) X He, X Chen, H Zhang, T Xie, XY Ye Expert Opinion on Therapeutic Patents 29 (2), 137-149, 2019 | 53 | 2019 |
Discovery of natural anti-inflammatory alkaloids: Potential leads for the drug discovery for the treatment of inflammation R Bai, C Yao, Z Zhong, J Ge, Z Bai, X Ye, T Xie, Y Xie European Journal of Medicinal Chemistry 213, 113165, 2021 | 49 | 2021 |
Oxidative stress: The core pathogenesis and mechanism of Alzheimer’s disease R Bai, J Guo, XY Ye, Y Xie, T Xie Ageing Research Reviews, 101619, 2022 | 41 | 2022 |
A concise total synthesis of triptolide D Yang, XY Ye, M Xu, KW Pang, N Zou, RM Letcher The Journal of Organic Chemistry 63 (19), 6446-6447, 1998 | 39 | 1998 |
Dual inhibitors of histone deacetylases and other cancer-related targets: a pharmacological perspective Y Gao, H Zhang, F Lirussi, C Garrido, XY Ye, T Xie Biochemical Pharmacology 182, 114224, 2020 | 37 | 2020 |
Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor α selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl) methoxy) benzyl … J Li, LJ Kennedy, Y Shi, S Tao, XY Ye, SY Chen, Y Wang, AS Hernandez, ... Journal of medicinal chemistry 53 (7), 2854-2864, 2010 | 32 | 2010 |
Anti-tumor drug discovery based on natural product β-elemene: Anti-tumor mechanisms and structural modification Z Bai, C Yao, J Zhu, Y Xie, XY Ye, R Bai, T Xie Molecules 26 (6), 1499, 2021 | 31 | 2021 |
Small molecule DNA-PK inhibitors as potential cancer therapy: A patent review (2010–present) S Hu, Z Hui, F Lirussi, C Garrido, XY Ye, T Xie Expert Opinion on Therapeutic Patents 31 (5), 435-452, 2021 | 26 | 2021 |
Synthesis and structure–activity relationship of dihydrobenzofuran derivatives as novel human GPR119 agonists XY Ye, CL Morales, Y Wang, KA Rossi, SE Malmstrom, M Abousleiman, ... Bioorganic & Medicinal Chemistry Letters 24 (11), 2539-2545, 2014 | 23 | 2014 |
Synthesis and structure–activity relationship of 2-adamantylmethyl tetrazoles as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) XY Ye, D Yoon, SY Chen, A Nayeem, R Golla, R Seethala, M Wang, ... Bioorganic & Medicinal Chemistry Letters 24 (2), 654-660, 2014 | 22 | 2014 |
Medicinal chemistry updates of novel HDACs inhibitors (2020 to present) X He, Z Hui, L Xu, R Bai, Y Gao, Z Wang, T Xie, XY Ye European Journal of Medicinal Chemistry 227, 113946, 2022 | 21 | 2022 |
Novel selective histone deacetylase 6 (HDAC6) inhibitors: a patent review (2016-2019) X He, Z Li, XT Zhuo, Z Hui, T Xie, XY Ye Recent Patents on Anti-Cancer Drug Discovery 15 (1), 32-48, 2020 | 19 | 2020 |
Natural terpenoids with anti-inflammatory activities: Potential leads for anti-inflammatory drug discovery J Ge, Z Liu, Z Zhong, L Wang, X Zhuo, J Li, X Jiang, XY Ye, T Xie, R Bai Bioorganic Chemistry, 105817, 2022 | 18 | 2022 |