Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 879 | 2015 |
Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork C Hertweck, A Luzhetskyy, Y Rebets, A Bechthold Natural product reports 24 (1), 162-190, 2007 | 682 | 2007 |
Chemical and biochemical aspects of deoxysugars and deoxysugar oligosaccharides A Kirschning, AFW Bechthold, J Rohr Bioorganic Chemistry Deoxysugars, Polyketides and Related Classes: Synthesis …, 1997 | 267 | 1997 |
Genes and enzymes involved in deoxysugar biosynthesis in bacteria A Trefzer, A Bechthold, JA Salas Natural product reports 16 (3), 283-299, 1999 | 225 | 1999 |
Genes and Enzymes Involved in Caffeic Acid Biosynthesis in the Actinomycete Saccharothrix espanaensis M Berner, D Krug, C Bihlmaier, A Vente, R Müller, A Bechthold Journal of bacteriology 188 (7), 2666-2673, 2006 | 206 | 2006 |
Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tü57 and … G Weitnauer, A Mühlenweg, A Trefzer, D Hoffmeister, RD Süssmuth, ... Chemistry & Biology 8 (6), 569-581, 2001 | 194 | 2001 |
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis L Westrich, S Domann, B Faust, D Bedford, DA Hopwood, A Bechthold FEMS microbiology letters 170 (2), 381-387, 1999 | 184 | 1999 |
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tü22: sequence analysis and expression in a heterologous host K Ichinose, DJ Bedford, D Tornus, A Bechthold, MJ Bibb, WP Revill, ... Chemistry & biology 5 (11), 647-659, 1998 | 183 | 1998 |
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic A Trefzer, S Pelzer, J Schimana, S Stockert, C Bihlmaier, HP Fiedler, ... Antimicrobial agents and chemotherapy 46 (5), 1174-1182, 2002 | 161 | 2002 |
Cloning of an avilamycin biosynthetic gene cluster from Streptomyces viridochromogenes Tü57 S Gaisser, A Trefzer, S Stockert, A Kirschning, A Bechthold Journal of bacteriology 179 (20), 6271-6278, 1997 | 156 | 1997 |
Function of glycosyltransferase genes involved in urdamycin A biosynthesis A Trefzer, D Hoffmeister, E Künzel, S Stockert, G Weitnauer, L Westrich, ... Chemistry & biology 7 (2), 133-142, 2000 | 155* | 2000 |
A genomic screening approach to the structure‐guided identification of drug candidates from natural sources A Hornung, M Bertazzo, A Dziarnowski, K Schneider, K Welzel, ... ChemBioChem 8 (7), 757-766, 2007 | 147 | 2007 |
Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tu2717 B Faust, D Hoffmeister, G Weitnauer, L Westrich, S Haag, P Schneider, ... Microbiology 146 (1), 147-154, 2000 | 140 | 2000 |
The glycosyltransferase UrdGT2 catalyzes both C‐and O‐glycosidic sugar transfers C Dürr, D Hoffmeister, SE Wohlert, K Ichinose, M Weber, U Von Mulert, ... Angewandte Chemie International Edition 43 (22), 2962-2965, 2004 | 138 | 2004 |
The NDP-sugar co-substrate concentration and the enzyme expression level influence the substrate specificity of glycosyltransferases: cloning and characterization of deoxysugar … D Hoffmeister, K Ichinose, S Domann, B Faust, A Trefzer, G Dräger, ... Chemistry & Biology 7 (11), 821-831, 2000 | 133 | 2000 |
Site-specific recombination strategies for engineering actinomycete genomes S Herrmann, T Siegl, M Luzhetska, L Petzke, C Jilg, E Welle, A Erb, ... Applied and environmental microbiology 78 (6), 1804-1812, 2012 | 131 | 2012 |
Identification of a sugar flexible glycosyltransferase from Streptomyces olivaceus, the producer of the antitumor polyketide elloramycin G Blanco, EP Patallo, AF Braña, A Trefzer, A Bechthold, J Rohr, ... Chemistry & biology 8 (3), 253-263, 2001 | 129 | 2001 |
Engineered urdamycin glycosyltransferases are broadened and altered in substrate specificity D Hoffmeister, B Wilkinson, G Foster, PJ Sidebottom, K Ichinose, ... Chemistry & biology 9 (3), 287-295, 2002 | 120 | 2002 |
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways A Trefzer, G Blanco, L Remsing, E Künzel, U Rix, F Lipata, AF Braña, ... Journal of the American Chemical Society 124 (21), 6056-6062, 2002 | 118 | 2002 |
Structure and action of the C–C bond-forming glycosyltransferase UrdGT2 involved in the biosynthesis of the antibiotic urdamycin M Mittler, A Bechthold, GE Schulz Journal of molecular biology 372 (1), 67-76, 2007 | 108 | 2007 |