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Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis N Cabezas-Wallscheid, D Klimmeck, J Hansson, DB Lipka, A Reyes, ... Cell stem cell 15 (4), 507-522, 2014 | 574 | 2014 |
DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia CC Oakes, M Seifert, Y Assenov, L Gu, M Przekopowitz, AS Ruppert, ... Nature genetics 48 (3), 253-264, 2016 | 322 | 2016 |
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats D Brocks, CR Schmidt, M Daskalakis, HS Jang, NM Shah, D Li, J Li, ... Nature genetics 49 (7), 1052-1060, 2017 | 274 | 2017 |
Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer D Brocks, Y Assenov, S Minner, O Bogatyrova, R Simon, C Koop, ... Cell reports 8 (3), 798-806, 2014 | 269 | 2014 |
Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia CC Oakes, R Claus, L Gu, Y Assenov, J Hüllein, M Zucknick, M Bieg, ... Cancer discovery 4 (3), 348-361, 2014 | 161 | 2014 |
Quiescence-induced LncRNAs trigger H4K20 trimethylation and transcriptional silencing H Bierhoff, MA Dammert, D Brocks, S Dambacher, G Schotta, I Grummt Molecular cell 54 (4), 675-682, 2014 | 153 | 2014 |
RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia DB Lipka, T Witte, R Toth, J Yang, M Wiesenfarth, P Nöllke, A Fischer, ... Nature communications 8 (1), 2126, 2017 | 114 | 2017 |
Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation N Blagitko-Dorfs, P Schlosser, G Greve, D Pfeifer, R Meier, A Baude, ... Leukemia 33 (4), 945-956, 2019 | 85 | 2019 |
Integrative analysis defines distinct prognostic subgroups of intrahepatic cholangiocarcinoma B Goeppert, R Toth, S Singer, T Albrecht, DB Lipka, P Lutsik, D Brocks, ... Hepatology 69 (5), 2091-2106, 2019 | 77 | 2019 |
Reactivation of endogenous retroviral elements via treatment with DNMT-and HDAC-inhibitors M Daskalakis, D Brocks, YH Sheng, MS Islam, A Ressnerova, Y Assenov, ... Cell Cycle 17 (7), 811-822, 2018 | 69 | 2018 |
Intratumor heterogeneity in epigenetic patterns Y Assenov, D Brocks, C Gerhäuser Seminars in cancer biology 51, 12-21, 2018 | 66 | 2018 |
Mobile genomics: tools and techniques for tackling transposons K O'Neill, D Brocks, MG Hammell Philosophical Transactions of the Royal Society B 375 (1795), 20190345, 2020 | 47 | 2020 |
Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite … DB Lipka, Q Wang, N Cabezas-Wallscheid, D Klimmeck, D Weichenhan, ... Cell Cycle 13 (22), 3476-3487, 2014 | 40 | 2014 |
ICGC Early Onset Prostate Cancer Project: Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer D Brocks, Y Assenov, S Minner, O Bogatyrova, R Simon, C Koop, ... Cell Rep 8 (3), 798-806, 2014 | 18 | 2014 |
Musical patterns for comparative epigenomics D Brocks Clinical Epigenetics 7, 1-5, 2015 | 16 | 2015 |
Single cell analysis reveals dynamics of transposable element transcription following epigenetic de-repression D Brocks, E Chomsky, Z Mukamel, A Lifshitz, A Tanay BioRxiv, 462853, 2018 | 12 | 2018 |