Quantitative pharmacokinetic and biodistribution studies for fluorescent imaging agents Y Feng, S Pannem, S Hodge, C Rounds, KM Tichauer, KD Paulsen, ... Biomedical Optics Express 15 (3), 1861-1877, 2024 | 3 | 2024 |
Improved intraoperative identification of close margins in oral squamous cell carcinoma resections using a dual aperture fluorescence ratio approach: first in-human results CC Rounds, JG de Wit, J Vonk, J Vorjohan, S Nelson, A Trang, B Villinski, ... Journal of Biomedical Optics 29 (1), 016003-016003, 2024 | 3 | 2024 |
Rapid, variable aperture approach to quantify depth of fluorescence in a heterogenous medium CC Rounds, J de Wit, J Vonk, F Voskuil, J Vorjohan, S Nelson, B Villinski, ... Molecular-Guided Surgery: Molecules, Devices, and Applications IX 12361, 21-24, 2023 | 3 | 2023 |
Quantifying Imaging Agent Binding and Dissociation in 3-D Cancer Spheroid Tissue Culture Using Paired-Agent Principles C Li, CC Rounds, VC Torres, Y He, X Xu, G Papavasiliou, KS Samkoe, ... Annals of biomedical engineering 52 (6), 1625-1637, 2024 | 1 | 2024 |
Ex vivo detection of oral squamous cell carcinoma spread to lymph nodes using paired-agent fluorescence optical tomography: path to clinical translation A Sharma, CC Rounds, TS Nijboer, F Voskuil, MJH Witjes, JG Brankov, ... Molecular-Guided Surgery: Molecules, Devices, and Applications X 12825, 27-35, 2024 | 1 | 2024 |
A paired-agent fluorescent molecular imaging strategy for quantifying antibody drug target engagement in in vivo window chamber xenograft models E Kayaalp-Nalbant, C Rounds, N Sadeghipour, B Meng, MR Folaron, ... Visualizing and Quantifying Drug Distribution in Tissue IV 11219, 29-32, 2020 | 1 | 2020 |
First clinical application of paired-agent imaging to intraoperatively detect cancer spread in excised sentinel lymph nodes from patients with head and neck cancer A Sharma, TS Nijboer, CC Rounds, JG Brankov, F Voskuil, MJH Witjes, ... Clinical Biophotonics III 13009, 41-47, 2024 | | 2024 |
A dual-aperture fluorescence ratio approach to minimize optical property heterogeneities for direct applications in intraoperative fluorescence-guided surgery CC Rounds, JG de Wit, J Vonk, J Vorjohan, S Nelson, A Trang, B Villinski, ... Clinical Biophotonics III 13009, 36-40, 2024 | | 2024 |
Addition of an ECM remodeling drug improves target engagement of immunotherapy in solid pancreatic cancer tumors CC Rounds, D Rabei, J Williams, S Haque, D Ranjan, C Li, R Cisek, ... Visualizing and Quantifying Drug Distribution in Tissue VIII 12821, 1282102, 2024 | | 2024 |
A dual-aperture fluorescence ratio approach to guide margin assessment intraoperatively in head and neck cancer surgery CC Rounds, JG de Wit, J Vonk, J Vorjohan, S Nelson, B Villinski, A Trang, ... Molecular-Guided Surgery: Molecules, Devices, and Applications X 12825, 1282502, 2024 | | 2024 |
Quantitative tissue biodistribution of fluorescence imaging agents in orthotopic mouse model of head and neck squamous cell carcinoma Y Feng, C Rounds, KM Tichauer, KS Samkoe Visualizing and Quantifying Drug Distribution in Tissue VIII 12821, 32-36, 2024 | | 2024 |
A cadaveric breast cancer tissue phantom for phase‐contrast X‐ray imaging applications CC Rounds, C Li, W Zhou, KM Tichauer, JG Brankov Animal Models and Experimental Medicine 6 (5), 427-432, 2023 | | 2023 |
Rapid detection of lymph node micro metastasis using widefield paired-agent fluorescent imaging techniques in the angular domain CC Rounds, VC Torres, C Li, F Voskuil, TS Nijboer, MJH Witjes, ... Optical Molecular Probes, Imaging and Drug Delivery, OM3E. 5, 2023 | | 2023 |
Margin status assessment using a ratio-metric angular domain fluorescent imaging approach in patients with head and neck squamous cell carcinoma CC Rounds, J de Wit, J Vonk, F Voskuil, MJH Witjes, KM Tichauer Optical Molecular Probes, Imaging and Drug Delivery, OW3E. 3, 2023 | | 2023 |
Higher density of ECM composition in pancreatic cancer correlates with reduced drug delivery CC Rounds, S Haque, C Li, D Nissen, D Ranjan, M Vaicik, ... Visualizing and Quantifying Drug Distribution in Tissue VII 12357, 7-11, 2023 | | 2023 |
Fluorescence mesoscopic imaging of whole lymph nodes for intraoperative sentinel lymph node biopsy procedures KM Tichauer, C Rounds, VC Torres, C Li, H Nguyen, TS Nijboer, ... Molecular-Guided Surgery: Molecules, Devices, and Applications IX 12361, 71-76, 2023 | | 2023 |
Intraoperative detection of insufficient surgical margins in head and neck cancer resection using dual aperture fluorescence ratio imaging KM Tichauer, CC Rounds, J d Wit, JL Vonk, J Vorjohan, JG Brankov, ... | | 2023 |
Intraoperative micrometastases detection using paired-agent fluorescent imaging: trial-and-error protocol development C Li, VC Torres, Y He, X Xu, C Rounds, S Nelson, KS Samkoe, ... Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems …, 2021 | | 2021 |
Intraoperative Assessment of Surgical Margins in Cancer Resection Surgery Via the Sub-Diffuse Optical Tomography" S-DOT" SR Nelson, BC Villinski, A Trang, JM Vorjohan, C Rounds, MJH Witjes, ... Illinois Tech Undergraduate Research Journal 1 (1), 5-5, 2021 | | 2021 |
Supplement 1 Quantitative pharmacokinetic and biodistribution studies for fluorescent imaging agents Y FENG, S PANNEM, S HODGE, C ROUNDS, KM TICHAUER, ... | | |