Kinetic and inhibition studies on human Jumonji-C (JmjC) domain-containing protein 5 A Tumber, E Salah, L Brewitz, TP Corner, CJ Schofield RSC Chemical Biology 4 (6), 399-413, 2023 | 7 | 2023 |
Structure-guided optimisation of N-hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-α TP Corner, RZR Teo, Y Wu, E Salah, Y Nakashima, G Fiorini, A Tumber, ... Chemical Science 14 (43), 12098-12120, 2023 | 6 | 2023 |
5-Substituted pyridine-2, 4-dicarboxylate derivatives have potential for selective inhibition of human jumonji-C domain-containing protein 5 L Brewitz, Y Nakashima, SK Piasecka, E Salah, SC Fletcher, A Tumber, ... Journal of Medicinal Chemistry 66 (15), 10849-10865, 2023 | 4 | 2023 |
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia H Lawson, JP Holt-Martyn, V Dembitz, Y Kabayama, LM Wang, A Bellani, ... Nature Cancer, 1-22, 2024 | 3 | 2024 |
Transfer of photochemistry from UV to visible: An expedient access to a bridged pyrrolidine O Lorthioir, T Corner, S Demanze, R Greenwood, K Proctor, S Stokes, ... Tetrahedron Letters 84, 153447, 2021 | 3 | 2021 |
Selective targeting of human TET1 by cyclic peptide inhibitors: Insights from biochemical profiling K Šimelis, H Saraç, E Salah, K Nishio, TE McAllister, TP Corner, A Tumber, ... Bioorganic & Medicinal Chemistry 99, 117597, 2024 | 1 | 2024 |
Innenrücktitelbild: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. 40/2024) Y Wu, Y Chen, TP Corner, Y Nakashima, E Salah, Z Li, L Zhang, L Yang, ... Angewandte Chemie 136 (40), e202414504, 2024 | | 2024 |
Inside Back Cover: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. Int. Ed. 40/2024) Y Wu, Y Chen, TP Corner, Y Nakashima, E Salah, Z Li, L Zhang, L Yang, ... Angewandte Chemie International Edition 63 (40), e202414504, 2024 | | 2024 |
A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity Y Wu, Y Chen, TP Corner, Y Nakashima, E Salah, Z Li, L Zhang, L Yang, ... Angewandte Chemie International Edition, e202410438, 2024 | | 2024 |
Crystallographic and Selectivity Studies on the Approved HIF Prolyl Hydroxylase Inhibitors Desidustat and Enarodustat TP Corner, E Salah, A Tumber, S Kaur, Y Nakashima, MD Allen, ... ChemMedChem, e202400504, 0 | | |