NADPH–cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology DS Riddick, X Ding, CR Wolf, TD Porter, AV Pandey, QY Zhang, J Gu, ... Drug Metabolism and Disposition 41 (1), 12-23, 2013 | 136 | 2013 |
Importance of drug pharmacokinetics at the site of action ML Rizk, L Zou, RM Savic, KE Dooley Clinical and translational science 10 (3), 133, 2017 | 96 | 2017 |
The activities of drug inactive ingredients on biological targets J Pottel, D Armstrong, L Zou, A Fekete, XP Huang, H Torosyan, ... Science 369 (6502), 403-413, 2020 | 54 | 2020 |
Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content. GKM Liang X, Yee SW, Chien HC, Chen EC, Luo Q, Zou L, Piao M, Mifune A, Chen ... PLoS Biol., 2018 | 47 | 2018 |
Molecular Mechanisms for Species Differences in Organic Anion Transporter 1, OAT1: Implications for Renal Drug Toxicity. GKM Zou L, Stecula A, Gupta A, Prasad B, Chien HC, Yee SW, Wang L, Unadkat ... Mol Pharmacol., 2018 | 35 | 2018 |
Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives L Zou, P Spanogiannopoulos, LM Pieper, HC Chien, W Cai, N Khuri, ... Proceedings of the National Academy of Sciences 117 (27), 16009-16018, 2020 | 31 | 2020 |
Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies SW Yee, A Stecula, HC Chien, L Zou, EV Feofanova, M van Borselen, ... PLoS genetics 15 (9), e1008208, 2019 | 21 | 2019 |
Rapid suppression of 7-dehydrocholesterol reductase activity in keratinocytes by vitamin D L Zou, TD Porter The Journal of steroid biochemistry and molecular biology 148, 64-71, 2015 | 21 | 2015 |
Deorphaning a solute carrier 22 family member, SLC22A15, through functional genomic studies SW Yee, D Buitrago, A Stecula, HX Ngo, HC Chien, L Zou, ML Koleske, ... FASEB journal: official publication of the Federation of American Societies …, 2020 | 19 | 2020 |
Interactions of oral molecular excipients with breast cancer resistance protein, BCRP L Zou, J Pottel, N Khuri, HX Ngo, Z Ni, E Tsakalozou, MS Warren, ... Molecular pharmaceutics 17 (3), 748-756, 2020 | 15 | 2020 |
7-Dehydrocholesterol reductase activity is independent of cytochrome P450 reductase L Zou, L Li, TD Porter The Journal of steroid biochemistry and molecular biology 127 (3-5), 435-438, 2011 | 15 | 2011 |
Suppression of cytochrome P450 reductase (POR) expression in hepatoma cells replicates the hepatic lipidosis observed in hepatic POR-null mice TD Porter, S Banerjee, EI Stolarczyk, L Zou Drug metabolism and disposition 39 (6), 966-973, 2011 | 13 | 2011 |
Drug metabolites potently inhibit renal organic anion transporters, OAT1 and OAT3 L Zou, P Matsson, A Stecula, HX Ngo, AA Zur, KM Giacomini Journal of pharmaceutical sciences 110 (1), 347-353, 2021 | 12 | 2021 |
A molecular basis for innovation in drug excipients JJ Irwin, J Pottel, L Zou, H Wen, S Zuk, X Zhang, T Sterling, BK Shoichet, ... Clinical Pharmacology & Therapeutics 101 (3), 320-323, 2017 | 12 | 2017 |
Drugs in COVID‐19 clinical trials: predicting transporter‐mediated drug‐drug interactions using in vitro assays and real‐world data SW Yee, B Vora, T Oskotsky, L Zou, S Jakobsen, OJ Enogieru, ... Clinical Pharmacology & Therapeutics 110 (1), 108-122, 2021 | 11 | 2021 |
Oxypurinol pharmacokinetics and pharmacodynamics in healthy volunteers: Influence of BCRP Q141K polymorphism and patient characteristics B Vora, DJ Brackman, L Zou, M Garcia‐Cremades, M Sirota, RM Savic, ... Clinical and translational science 14 (4), 1431-1443, 2021 | 8 | 2021 |
Impact of pharmaceutical excipients on oral drug absorption: a focus on intestinal drug transporters L Zou, Z Ni, E Tsakalozou, KM Giacomini Clinical pharmacology and therapeutics 105 (2), 323-325, 2019 | 8 | 2019 |
Scientific considerations for global drug development JL Wilson, KWK Cheung, L Lin, EAE Green, AI Porrás, L Zou, D Mukanga, ... Science translational medicine 12 (554), eaax2550, 2020 | 5 | 2020 |
Interaction of commonly used oral molecular excipients with P-glycoprotein R Bajaj, LB Chong, L Zou, E Tsakalozou, Z Ni, KM Giacomini, DL Kroetz The AAPS Journal 23, 1-12, 2021 | 4 | 2021 |
New and emerging research on solute carrier (SLC) and ABC transporters in drug discovery and development: Outlook from the International Transporter Consortium. KM Giacomini, SW Yee, ML Koleske, L Zou, P Matsson, E Chen, ... Clinical Pharmacology and Therapeutics, 2022 | 2 | 2022 |