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Ling Zou
Ling Zou
在 amgen.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
NADPH–cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology
DS Riddick, X Ding, CR Wolf, TD Porter, AV Pandey, QY Zhang, J Gu, ...
Drug Metabolism and Disposition 41 (1), 12-23, 2013
1362013
Importance of drug pharmacokinetics at the site of action
ML Rizk, L Zou, RM Savic, KE Dooley
Clinical and translational science 10 (3), 133, 2017
962017
The activities of drug inactive ingredients on biological targets
J Pottel, D Armstrong, L Zou, A Fekete, XP Huang, H Torosyan, ...
Science 369 (6502), 403-413, 2020
542020
Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content.
GKM Liang X, Yee SW, Chien HC, Chen EC, Luo Q, Zou L, Piao M, Mifune A, Chen ...
PLoS Biol., 2018
472018
Molecular Mechanisms for Species Differences in Organic Anion Transporter 1, OAT1: Implications for Renal Drug Toxicity.
GKM Zou L, Stecula A, Gupta A, Prasad B, Chien HC, Yee SW, Wang L, Unadkat ...
Mol Pharmacol., 2018
352018
Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives
L Zou, P Spanogiannopoulos, LM Pieper, HC Chien, W Cai, N Khuri, ...
Proceedings of the National Academy of Sciences 117 (27), 16009-16018, 2020
312020
Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies
SW Yee, A Stecula, HC Chien, L Zou, EV Feofanova, M van Borselen, ...
PLoS genetics 15 (9), e1008208, 2019
212019
Rapid suppression of 7-dehydrocholesterol reductase activity in keratinocytes by vitamin D
L Zou, TD Porter
The Journal of steroid biochemistry and molecular biology 148, 64-71, 2015
212015
Deorphaning a solute carrier 22 family member, SLC22A15, through functional genomic studies
SW Yee, D Buitrago, A Stecula, HX Ngo, HC Chien, L Zou, ML Koleske, ...
FASEB journal: official publication of the Federation of American Societies …, 2020
192020
Interactions of oral molecular excipients with breast cancer resistance protein, BCRP
L Zou, J Pottel, N Khuri, HX Ngo, Z Ni, E Tsakalozou, MS Warren, ...
Molecular pharmaceutics 17 (3), 748-756, 2020
152020
7-Dehydrocholesterol reductase activity is independent of cytochrome P450 reductase
L Zou, L Li, TD Porter
The Journal of steroid biochemistry and molecular biology 127 (3-5), 435-438, 2011
152011
Suppression of cytochrome P450 reductase (POR) expression in hepatoma cells replicates the hepatic lipidosis observed in hepatic POR-null mice
TD Porter, S Banerjee, EI Stolarczyk, L Zou
Drug metabolism and disposition 39 (6), 966-973, 2011
132011
Drug metabolites potently inhibit renal organic anion transporters, OAT1 and OAT3
L Zou, P Matsson, A Stecula, HX Ngo, AA Zur, KM Giacomini
Journal of pharmaceutical sciences 110 (1), 347-353, 2021
122021
A molecular basis for innovation in drug excipients
JJ Irwin, J Pottel, L Zou, H Wen, S Zuk, X Zhang, T Sterling, BK Shoichet, ...
Clinical Pharmacology & Therapeutics 101 (3), 320-323, 2017
122017
Drugs in COVID‐19 clinical trials: predicting transporter‐mediated drug‐drug interactions using in vitro assays and real‐world data
SW Yee, B Vora, T Oskotsky, L Zou, S Jakobsen, OJ Enogieru, ...
Clinical Pharmacology & Therapeutics 110 (1), 108-122, 2021
112021
Oxypurinol pharmacokinetics and pharmacodynamics in healthy volunteers: Influence of BCRP Q141K polymorphism and patient characteristics
B Vora, DJ Brackman, L Zou, M Garcia‐Cremades, M Sirota, RM Savic, ...
Clinical and translational science 14 (4), 1431-1443, 2021
82021
Impact of pharmaceutical excipients on oral drug absorption: a focus on intestinal drug transporters
L Zou, Z Ni, E Tsakalozou, KM Giacomini
Clinical pharmacology and therapeutics 105 (2), 323-325, 2019
82019
Scientific considerations for global drug development
JL Wilson, KWK Cheung, L Lin, EAE Green, AI Porrás, L Zou, D Mukanga, ...
Science translational medicine 12 (554), eaax2550, 2020
52020
Interaction of commonly used oral molecular excipients with P-glycoprotein
R Bajaj, LB Chong, L Zou, E Tsakalozou, Z Ni, KM Giacomini, DL Kroetz
The AAPS Journal 23, 1-12, 2021
42021
New and emerging research on solute carrier (SLC) and ABC transporters in drug discovery and development: Outlook from the International Transporter Consortium.
KM Giacomini, SW Yee, ML Koleske, L Zou, P Matsson, E Chen, ...
Clinical Pharmacology and Therapeutics, 2022
22022
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