Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration WS Hambright, RS Fonseca, L Chen, R Na, Q Ran Redox biology 12, 8-17, 2017 | 686 | 2017 |
Ablation of the ferroptosis inhibitor glutathione peroxidase 4 in neurons results in rapid motor neuron degeneration and paralysis L Chen, WS Hambright, R Na, Q Ran Journal of Biological Chemistry 290 (47), 28097-28106, 2015 | 429 | 2015 |
Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson–Gilford Progeria Syndrome X Mu, C Tseng, WS Hambright, P Matre, CY Lin, P Chanda, W Chen, J Gu, ... Aging Cell 19 (8), e13152, 2020 | 59 | 2020 |
Regulation of stomatal defense by air relative humidity S Panchal, R Chitrakar, BK Thompson, N Obulareddy, D Roy, ... Plant physiology 172 (3), 2021-2032, 2016 | 58 | 2016 |
Rapamycin rescues age-related changes in muscle-derived stem/progenitor cells from progeroid mice Y Kawakami, WS Hambright, K Takayama, X Mu, A Lu, JH Cummins, ... Molecular Therapy Methods & Clinical Development 14, 64-76, 2019 | 42 | 2019 |
Murine models of accelerated aging and musculoskeletal disease WS Hambright, LJ Niedernhofer, J Huard, PD Robbins Bone 125, 122-127, 2019 | 30 | 2019 |
Development of an ecophysiological model for Diplosphaera colotermitum TAV2, a termite hindgut Verrucomicrobium J Isanapong, WS Hambright, AG Willis, A Boonmee, SJ Callister, ... The ISME journal 7 (9), 1803-1813, 2013 | 28 | 2013 |
Ursolic acid protects monocytes against metabolic stress-induced priming and dysfunction by preventing the induction of Nox4 SL Ullevig, HS Kim, HN Nguyen, WS Hambright, AJ Robles, S Tavakoli, ... Redox Biology 2, 259-266, 2014 | 25 | 2014 |
Cellular expansion of MSCs: Shifting the regenerative potential K Miclau, WS Hambright, J Huard, MJ Stoddart, CS Bahney Aging Cell 22 (1), e13759, 2023 | 22 | 2023 |
The Senolytic Drug Fisetin Attenuates Bone Degeneration in the Zmpste24−/− Progeria Mouse Model WS Hambright, X Mu, X Gao, P Guo, Y Kawakami, J Mitchell, M Mullen, ... Journal of Osteoporosis 2023 (1), 5572754, 2023 | 18 | 2023 |
Senolytic elimination of senescent macrophages restores muscle stem cell function in severely dystrophic muscle L Liu, X Yue, Z Sun, WS Hambright, Q Feng, Y Cui, J Huard, PD Robbins, ... Aging (Albany NY) 14 (19), 7650, 2022 | 17 | 2022 |
Mechanical strain drives exosome production, function, and miRNA cargo in C2C12 muscle progenitor cells M Mullen, K Williams, T LaRocca, V Duke, WS Hambright, SK Ravuri, ... Journal of Orthopaedic Research® 41 (6), 1186-1197, 2023 | 13 | 2023 |
Reduction of senescent fibro‐adipogenic progenitors in progeria‐aged muscle by senolytics rescues the function of muscle stem cells L Liu, X Yue, Z Sun, WS Hambright, J Wei, Y Li, P Matre, Y Cui, Z Wang, ... Journal of Cachexia, Sarcopenia and Muscle 13 (6), 3137-3148, 2022 | 13 | 2022 |
Aberrant RhoA activation in macrophages increases senescence-associated secretory phenotypes and ectopic calcification in muscular dystrophic mice X Mu, CY Lin, WS Hambright, Y Tang, S Ravuri, A Lu, P Matre, W Chen, ... Aging (Albany NY) 12 (24), 24853, 2020 | 12 | 2020 |
Nuclear softening mediated by Sun2 suppression delays mechanical stress-induced cellular senescence X Yue, J Cui, Z Sun, L Liu, Y Li, L Shao, Q Feng, Z Wang, WS Hambright, ... Cell Death Discovery 9 (1), 167, 2023 | 10 | 2023 |
Rapamycin for aging stem cells WS Hambright, MJ Philippon, J Huard Aging (Albany NY) 12 (15), 15184, 2020 | 9 | 2020 |
Fisetin attenuates cellular senescence accumulation during culture expansion of human adipose-derived stem cells M Mullen, AL Nelson, A Goff, J Billings, H Kloser, C Huard, J Mitchell, ... Stem Cells 41 (7), 698-710, 2023 | 5 | 2023 |
Biologics for skeletal muscle healing: the role of senescence and platelet-based treatment modalities V Oberlohr, H Lengel, WS Hambright, KE Whitney, TA Evans, J Huard Operative Techniques in Sports Medicine 28 (3), 150754, 2020 | 4 | 2020 |
The senolytic drug fisetin mitigates age‐related bone density loss in the progeroid mouse model Zmpste24−/− S Hambright, Y Kawakami, X Mu, X Gao, A Lu, J Kirkland, J Huard The FASEB Journal 34 (S1), 1-1, 2020 | 3 | 2020 |
Shewanella baltica ecotypes have wide transcriptional variation under the same growth conditions WS Hambright, J Deng, JM Tiedje, I Brettar, JLM Rodrigues Msphere 1 (5), 10.1128/msphere. 00158-16, 2016 | 3 | 2016 |