关注
Tristan Markle
Tristan Markle
Senior Researcher
在 sparc.bc.ca 的电子邮件经过验证
标题
引用次数
引用次数
年份
Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection
MA Brockman, ZL Brumme, CJ Brumme, T Miura, J Sela, PC Rosato, ...
Journal of virology 84 (22), 11937-11949, 2010
1522010
Attenuation of multiple Nef functions in HIV-1 elite controllers
P Mwimanzi, TJ Markle, E Martin, Y Ogata, XT Kuang, M Tokunaga, ...
Retrovirology 10, 1-12, 2013
982013
Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase–integrase sequences from HIV-1 elite controllers
ZL Brumme, C Li, T Miura, J Sela, PC Rosato, CJ Brumme, TJ Markle, ...
JAIDS Journal of Acquired Immune Deficiency Syndromes 56 (2), 100-108, 2011
812011
Nef proteins from HIV-1 elite controllers are inefficient at preventing antibody-dependent cellular cytotoxicity
N Alsahafi, S Ding, J Richard, T Markle, N Brassard, B Walker, GK Lewis, ...
Journal of virology 90 (6), 2993-3002, 2016
782016
Impaired Nef function is associated with early control of HIV-1 viremia
XT Kuang, X Li, G Anmole, P Mwimanzi, A Shahid, AQ Le, L Chong, ...
Journal of virology 88 (17), 10200-10213, 2014
492014
Genotypic and functional impact of HIV-1 adaptation to its host population during the North American epidemic
LA Cotton, XT Kuang, AQ Le, JM Carlson, B Chan, DR Chopera, ...
PLoS genetics 10 (4), e1004295, 2014
492014
HIV-1 Nef and T-cell activation: a history of contradictions
TJ Markle, P Mwimanzi, MA Brockman
Future virology 8 (4), 391-404, 2013
392013
Dynamic range of Nef functions in chronic HIV-1 infection
P Mwimanzi, TJ Markle, Y Ogata, E Martin, M Tokunaga, M Mahiti, ...
Virology 439 (2), 74-80, 2013
382013
Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity
MA Brockman, DR Chopera, A Olvera, CJ Brumme, J Sela, TJ Markle, ...
Journal of virology 86 (12), 6913-6923, 2012
342012
Human leukocyte antigen (HLA) class I down-regulation by human immunodeficiency virus type 1 negative factor (HIV-1 Nef): what might we learn from natural sequence variants?
P Mwimanzi, TJ Markle, T Ueno, MA Brockman
Viruses 4 (9), 1711-1730, 2012
312012
A robust and scalable TCR-based reporter cell assay to measure HIV-1 Nef-mediated T cell immune evasion
G Anmole, XT Kuang, M Toyoda, E Martin, A Shahid, AQ Le, T Markle, ...
Journal of immunological methods 426, 104-113, 2015
302015
Inhibition of NF-κB-dependent HIV-1 replication by the marine natural product bengamide A
I Tietjen, DE Williams, S Read, XT Kuang, P Mwimanzi, E Wilhelm, ...
Antiviral research 152, 94-103, 2018
252018
Brockman, M.A., et al., Human Leukocyte Antigen (HLA) Class I Down-Regulation by Human Immunodeficiency Virus Type 1 Negative Factor (HIV-1 Nef): What Might We Learn From …
P Mwimanzi, TJ Markle, T Ueno, MA Brockman
Viruses 4 (10), 2014-2015, 2012
102012
Modulation of TCR-dependent NFAT signaling is impaired in HIV-1 Nef isolates from elite controllers
SW Jin, TJ Markle, G Anmole, A Rahimi, XT Kuang, ZL Brumme, ...
Virology 530, 39-50, 2019
82019
In vitro functional assessment of natural HIV-1 group M Vpu sequences using a universal priming approach
A Rahimi, G Anmole, M Soto-Nava, T Escamilla-Gomez, T Markle, SW Jin, ...
Journal of virological methods 240, 32-41, 2017
62017
Impairment of viral replication capacity by nef alleles from HIV elite controllers
P Mwimanzi, T Markle, H Otsuka, Y Ogata, M Tokunaga, T Miura, E Martin, ...
Retrovirology 8, 1-1, 2011
42011
Kaufmann 498 DE, Brockman MA, Finzi A. 2016. Nef Proteins from HIV-1 Elite Controllers Are 499 Inefficient at Preventing Antibody-Dependent Cellular Cytotoxicity
N Alsahafi, S Ding, J Richard, T Markle, N Brassard, B Walker, GK Lewis
J Virol 90, 2993-500, 0
2
Impact of HLA selection pressure on HIV-1 evolution and fitness during the North American epidemic
L Cotton, XT Kuang, AQ Le, JM Carlson, B Chan, DR Chopera, ...
AIDS RESEARCH AND HUMAN RETROVIRUSES 29 (11), A177-A177, 2013
12013
AIDS Vaccine 2013October 7–10, 2013Barcelona, Spain
T Hertz
AIDS Research and Human Retroviruses 29 (11), A-1, 2013
12013
Molecular and functional consequences of immune-mediated evolution in HIV-1 Nef during the North American epidemic.
CJ Brumme, B Chan, T Markle, J Carlson, E Martin, QA Le, K Penney, ...
AIDS Research and Human Retroviruses 27 (10), 2011
12011
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