Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection MA Brockman, ZL Brumme, CJ Brumme, T Miura, J Sela, PC Rosato, ... Journal of virology 84 (22), 11937-11949, 2010 | 152 | 2010 |
Attenuation of multiple Nef functions in HIV-1 elite controllers P Mwimanzi, TJ Markle, E Martin, Y Ogata, XT Kuang, M Tokunaga, ... Retrovirology 10, 1-12, 2013 | 98 | 2013 |
Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase–integrase sequences from HIV-1 elite controllers ZL Brumme, C Li, T Miura, J Sela, PC Rosato, CJ Brumme, TJ Markle, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 56 (2), 100-108, 2011 | 81 | 2011 |
Nef proteins from HIV-1 elite controllers are inefficient at preventing antibody-dependent cellular cytotoxicity N Alsahafi, S Ding, J Richard, T Markle, N Brassard, B Walker, GK Lewis, ... Journal of virology 90 (6), 2993-3002, 2016 | 78 | 2016 |
Impaired Nef function is associated with early control of HIV-1 viremia XT Kuang, X Li, G Anmole, P Mwimanzi, A Shahid, AQ Le, L Chong, ... Journal of virology 88 (17), 10200-10213, 2014 | 49 | 2014 |
Genotypic and functional impact of HIV-1 adaptation to its host population during the North American epidemic LA Cotton, XT Kuang, AQ Le, JM Carlson, B Chan, DR Chopera, ... PLoS genetics 10 (4), e1004295, 2014 | 49 | 2014 |
HIV-1 Nef and T-cell activation: a history of contradictions TJ Markle, P Mwimanzi, MA Brockman Future virology 8 (4), 391-404, 2013 | 39 | 2013 |
Dynamic range of Nef functions in chronic HIV-1 infection P Mwimanzi, TJ Markle, Y Ogata, E Martin, M Tokunaga, M Mahiti, ... Virology 439 (2), 74-80, 2013 | 38 | 2013 |
Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity MA Brockman, DR Chopera, A Olvera, CJ Brumme, J Sela, TJ Markle, ... Journal of virology 86 (12), 6913-6923, 2012 | 34 | 2012 |
Human leukocyte antigen (HLA) class I down-regulation by human immunodeficiency virus type 1 negative factor (HIV-1 Nef): what might we learn from natural sequence variants? P Mwimanzi, TJ Markle, T Ueno, MA Brockman Viruses 4 (9), 1711-1730, 2012 | 31 | 2012 |
A robust and scalable TCR-based reporter cell assay to measure HIV-1 Nef-mediated T cell immune evasion G Anmole, XT Kuang, M Toyoda, E Martin, A Shahid, AQ Le, T Markle, ... Journal of immunological methods 426, 104-113, 2015 | 30 | 2015 |
Inhibition of NF-κB-dependent HIV-1 replication by the marine natural product bengamide A I Tietjen, DE Williams, S Read, XT Kuang, P Mwimanzi, E Wilhelm, ... Antiviral research 152, 94-103, 2018 | 25 | 2018 |
Brockman, M.A., et al., Human Leukocyte Antigen (HLA) Class I Down-Regulation by Human Immunodeficiency Virus Type 1 Negative Factor (HIV-1 Nef): What Might We Learn From … P Mwimanzi, TJ Markle, T Ueno, MA Brockman Viruses 4 (10), 2014-2015, 2012 | 10 | 2012 |
Modulation of TCR-dependent NFAT signaling is impaired in HIV-1 Nef isolates from elite controllers SW Jin, TJ Markle, G Anmole, A Rahimi, XT Kuang, ZL Brumme, ... Virology 530, 39-50, 2019 | 8 | 2019 |
In vitro functional assessment of natural HIV-1 group M Vpu sequences using a universal priming approach A Rahimi, G Anmole, M Soto-Nava, T Escamilla-Gomez, T Markle, SW Jin, ... Journal of virological methods 240, 32-41, 2017 | 6 | 2017 |
Impairment of viral replication capacity by nef alleles from HIV elite controllers P Mwimanzi, T Markle, H Otsuka, Y Ogata, M Tokunaga, T Miura, E Martin, ... Retrovirology 8, 1-1, 2011 | 4 | 2011 |
Kaufmann 498 DE, Brockman MA, Finzi A. 2016. Nef Proteins from HIV-1 Elite Controllers Are 499 Inefficient at Preventing Antibody-Dependent Cellular Cytotoxicity N Alsahafi, S Ding, J Richard, T Markle, N Brassard, B Walker, GK Lewis J Virol 90, 2993-500, 0 | 2 | |
Impact of HLA selection pressure on HIV-1 evolution and fitness during the North American epidemic L Cotton, XT Kuang, AQ Le, JM Carlson, B Chan, DR Chopera, ... AIDS RESEARCH AND HUMAN RETROVIRUSES 29 (11), A177-A177, 2013 | 1 | 2013 |
AIDS Vaccine 2013October 7–10, 2013Barcelona, Spain T Hertz AIDS Research and Human Retroviruses 29 (11), A-1, 2013 | 1 | 2013 |
Molecular and functional consequences of immune-mediated evolution in HIV-1 Nef during the North American epidemic. CJ Brumme, B Chan, T Markle, J Carlson, E Martin, QA Le, K Penney, ... AIDS Research and Human Retroviruses 27 (10), 2011 | 1 | 2011 |