TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics IR Mackenzie, AM Nicholson, M Sarkar, J Messing, MD Purice, C Pottier, ... Neuron 95 (4), 808-816. e9, 2017 | 568 | 2017 |
The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer’s disease BJ Matchett, LT Grinberg, P Theofilas, ME Murray Acta neuropathologica 141 (5), 631-650, 2021 | 104 | 2021 |
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in … C Pottier, Y Ren, RB Perkerson, M Baker, GD Jenkins, M van Blitterswijk, ... Acta neuropathologica 137, 879-899, 2019 | 100 | 2019 |
Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: Combined data from 13 community-based or population-based autopsy cohorts PT Nelson, C Brayne, ME Flanagan, EL Abner, S Agrawal, J Attems, ... Acta neuropathologica 144 (1), 27-44, 2022 | 87 | 2022 |
Pathological, imaging and genetic characteristics support the existence of distinct TDP-43 types in non-FTLD brains KA Josephs, ME Murray, N Tosakulwong, SD Weigand, AM Serie, ... Acta neuropathologica 137, 227-238, 2019 | 80 | 2019 |
Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease AM Crist, KM Hinkle, X Wang, CM Moloney, BJ Matchett, SA Labuzan, ... Nature communications 12 (1), 2311, 2021 | 51 | 2021 |
Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies X Zhou, AM Nicholson, Y Ren, M Brooks, P Jiang, A Zuberi, HN Phuoc, ... Brain 143 (6), 1905-1919, 2020 | 48 | 2020 |
White matter damage due to vascular, tau, and TDP-43 pathologies and its relevance to cognition S Raghavan, SA Przybelski, RI Reid, TG Lesnick, VK Ramanan, H Botha, ... Acta Neuropathologica Communications 10 (1), 16, 2022 | 21 | 2022 |
Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity AM Nicholson, X Zhou, RB Perkerson, TM Parsons, J Chew, M Brooks, ... Acta neuropathologica communications 6, 1-14, 2018 | 20 | 2018 |
Disruptions in endocytic traffic contribute to the activation of the NLRP3 inflammasome B Lee, C Hoyle, R Wellens, JP Green, F Martin-Sanchez, DM Williams, ... Science Signaling 16 (773), eabm7134, 2023 | 17 | 2023 |
Global neuropathologic severity of Alzheimer’s disease and locus coeruleus vulnerability influences plasma phosphorylated tau levels ME Murray, CM Moloney, N Kouri, JA Syrjanen, BJ Matchett, ... Molecular neurodegeneration 17 (1), 85, 2022 | 16 | 2022 |
Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease. Nat Commun 12: 1–17 AM Crist, KM Hinkle, X Wang, CM Moloney, BJ Matchett, SA Labuzan, ... | 11 | 2021 |
Loss of Tmem106b leads to cerebellum Purkinje cell death and motor deficits R Rademakers, AM Nicholson, Y Ren, S Koga, HP Nguyen, M Brooks, ... Brain Pathology 31 (3), 2021 | 9 | 2021 |
Retrospective evaluation of neuropathologic proxies of the minimal atrophy subtype compared with corticolimbic Alzheimer disease subtypes BDC Boon, SA Labuzan, Z Peng, BJ Matchett, N Kouri, KM Hinkle, ... Neurology 101 (14), e1412-e1423, 2023 | 2 | 2023 |
The SERPINA5 coding variant E228Q does not contribute to clinicopathologic characteristics in Alzheimer’s disease: A cross-sectional study BJ Matchett, SJ Lincoln, M Baker, N Tamvaka, SA Labuzan, TNH Sirmans, ... Medicine 102 (24), e34017, 2023 | | 2023 |
Cellular signaling, molecular activation, and regulation of the NLRP3 inflammasome R Wellens, B Matchett, D Brough, C Hoyle Inflammasome Biology, 51-65, 2023 | | 2023 |