A combinatorial library of lipid-like materials for delivery of RNAi therapeutics A Akinc, A Zumbuehl, M Goldberg, ES Leshchiner, V Busini, N Hossain, ... Nature biotechnology 26 (5), 561-569, 2008 | 1430 | 2008 |
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs C Wolfrum, S Shi, KN Jayaprakash, M Jayaraman, G Wang, RK Pandey, ... Nature biotechnology 25 (10), 1149-1157, 2007 | 1124 | 2007 |
Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms A Akinc, W Querbes, S De, J Qin, M Frank-Kamenetsky, KN Jayaprakash, ... Molecular Therapy 18 (7), 1357-1364, 2010 | 1096 | 2010 |
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates M Frank-Kamenetsky, A Grefhorst, NN Anderson, TS Racie, B Bramlage, ... Proceedings of the National Academy of Sciences 105 (33), 11915-11920, 2008 | 809 | 2008 |
Development of lipidoid–siRNA formulations for systemic delivery to the liver A Akinc, M Goldberg, J Qin, JR Dorkin, C Gamba-Vitalo, M Maier, ... Molecular Therapy 17 (5), 872-879, 2009 | 457 | 2009 |
Cardiac autonomic neuropathy in diabetes mellitus: prevalence, risk factors and utility of corrected QT interval in the ECG for its diagnosis JM Pappachan, J Sebastian, BC Bino, K Jayaprakash, K Vijayakumar, ... Postgraduate medical journal 84 (990), 205-210, 2008 | 186 | 2008 |
Alkene metathesis: new developments in catalyst design and application C Pariya, KN Jayaprakash, A Sarkar Coordination chemistry reviews 168, 1-48, 1998 | 141 | 1998 |
New family of solitary waves in granular dimer chains with no precompression KR Jayaprakash, Y Starosvetsky, AF Vakakis Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 83 (3 …, 2011 | 139 | 2011 |
Systemic RNAi-mediated gene silencing in nonhuman primate and rodent myeloid cells TI Novobrantseva, A Borodovsky, J Wong, B Klebanov, M Zafari, K Yucius, ... Molecular Therapy-Nucleic Acids 1, 2012 | 138 | 2012 |
Ferrocene in Conjugation with a Fischer Carbene: Synthesis, NLO, and Electrochemical Behavior of a Novel Organometallic Push− Pull System KN Jayaprakash, PC Ray, I Matsuoka, MM Bhadbhade, VG Puranik, ... Organometallics 18 (19), 3851-3858, 1999 | 134 | 1999 |
Versatile site-specific conjugation of small molecules to siRNA using click chemistry T Yamada, CG Peng, S Matsuda, H Addepalli, KN Jayaprakash, MR Alam, ... The Journal of organic chemistry 76 (5), 1198-1211, 2011 | 131 | 2011 |
Synthesis of a 28-mer oligosaccharide core of Mycobacterial lipoarabinomannan (LAM) requires only two n-pentenyl orthoester progenitors B Fraser-Reid, J Lu, KN Jayaprakash, JC Lopez Tetrahedron: Asymmetry 17 (17), 2449-2463, 2006 | 125 | 2006 |
Synthesis and Reactivity of a Coordinatively Unsaturated Ruthenium (II) Parent Amido Complex: Studies of X− H Activation (X= H or C) D Conner, KN Jayaprakash, TR Cundari, TB Gunnoe Organometallics 23 (11), 2724-2733, 2004 | 124 | 2004 |
Chemical modifications of monomers and oligonucleotides with cycloaddition M Manoharan, KG Rajeev, T Yamada, D Butler, NK Jayaprakash, ... US Patent 8,962,580, 2015 | 120 | 2015 |
Non-nucleoside building blocks for copper-assisted and copper-free click chemistry for the efficient synthesis of RNA conjugates KN Jayaprakash, CG Peng, D Butler, JP Varghese, MA Maier, KG Rajeev, ... Organic Letters 12 (23), 5410-5413, 2010 | 94 | 2010 |
Nonlinear normal modes and band zones in granular chains with no pre-compression KR Jayaprakash, Y Starosvetsky, AF Vakakis, M Peeters, G Kerschen Nonlinear Dynamics 63, 359-385, 2011 | 93 | 2011 |
Microalbuminuria in patients with essential hypertension and its relationship to target organ damage: an Indian experience B Hitha, JM Pappachan, HB Pillai, P Sujathan, CD Ramakrishna, ... Saudi Journal of Kidney Diseases and Transplantation 19 (3), 411-419, 2008 | 83 | 2008 |
Comparison of simultaneous estimation of cardiac output by four techniques in patients undergoing off-pump coronary artery bypass surgery-a prospective observational study M Chakravarthy, TA Patil, K Jayaprakash, P Kalligudd, D Prabhakumar, ... Annals of cardiac anaesthesia 10 (2), 121-126, 2007 | 79 | 2007 |
Synthesis of a Lipomannan Component of the Cell‐Wall Complex of Mycobacterium tuberculosis Is Based on Paulsen's Concept of Donor/Acceptor “Match” KN Jayaprakash, J Lu, B Fraser‐Reid Angewandte Chemie 117 (36), 6044-6048, 2005 | 79 | 2005 |
Synthesis of a malaria candidate glycosylphosphatidylinositol (GPI) structure: a strategy for fully inositol acylated and phosphorylated GPIs J Lu, KN Jayaprakash, U Schlueter, B Fraser-Reid Journal of the American Chemical Society 126 (24), 7540-7547, 2004 | 76 | 2004 |