The protein structures that shape caspase activity, specificity, activation and inhibition P Fuentes-Prior, GS Salvesen Biochemical Journal 384 (2), 201-232, 2004 | 1213 | 2004 |
Structural basis for the anticoagulant activity of the thrombin–thrombomodulin complex P Fuentes-Prior, Y Iwanaga, R Huber, R Pagila, G Rumennik, M Seto, ... Nature 404 (6777), 518-525, 2000 | 419 | 2000 |
Correlation between SMA type and SMN2 copy number revisited: an analysis of 625 unrelated Spanish patients and a compilation of 2834 reported cases M Calucho, S Bernal, L Alías, F March, A Venceslá, FJ Rodríguez-Álvarez, ... Neuromuscular Disorders 28 (3), 208-215, 2018 | 380 | 2018 |
Crystal structures of the membrane-binding C2 domain of human coagulation factor V S Macedo-Ribeiro, W Bode, R Huber, MA Quinn-Allen, SW Kim, TL Ortel, ... Nature 402 (6760), 434-439, 1999 | 325 | 1999 |
Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation R Friedrich, P Panizzi, P Fuentes-Prior, K Richter, I Verhamme, ... Nature 425 (6957), 535-539, 2003 | 323 | 2003 |
Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: demonstration in isolated monocytes from cystic fibrosis … C del Fresno, F García-Rio, V Gómez-Pina, A Soares-Schanoski, ... The Journal of Immunology 182 (10), 6494-6507, 2009 | 292 | 2009 |
Ionomycin-activated calpain triggers apoptosis: a probable role for Bcl-2 family members S Gil-Parrado, A Fernández-Montalván, I Assfalg-Machleidt, O Popp, ... Journal of Biological Chemistry 277 (30), 27217-27226, 2002 | 291 | 2002 |
Structural basis for the activation of human procaspase-7 SJ Riedl, P Fuentes-Prior, M Renatus, N Kairies, S Krapp, R Huber, ... Proceedings of the National Academy of Sciences 98 (26), 14790-14795, 2001 | 290 | 2001 |
Metalloproteinases shed TREM-1 ectodomain from lipopolysaccharide-stimulated human monocytes V Gomez-Pina, A Soares-Schanoski, A Rodriguez-Rojas, C Del Fresno, ... The Journal of Immunology 179 (6), 4065-4073, 2007 | 259 | 2007 |
The 2.0-Å crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems N Kairies, HG Beisel, P Fuentes-Prior, R Tsuda, T Muta, S Iwanaga, ... Proceedings of the National Academy of Sciences 98 (24), 13519-13524, 2001 | 192 | 2001 |
Mutation update of spinal muscular atrophy in Spain: molecular characterization of 745 unrelated patients and identification of four novel mutations in the SMN1 gene L Alías, S Bernal, P Fuentes-Prior, MJ Barceló, E Also, ... Human genetics 125, 29-39, 2009 | 190 | 2009 |
Molecular basis of protein S deficiency PG De Frutos, P Fuentes-Prior, B Hurtado, N Sala Thrombosis and haemostasis 98 (09), 543-556, 2007 | 187 | 2007 |
In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation P Panizzi, M Nahrendorf, JL Figueiredo, J Panizzi, B Marinelli, Y Iwamoto, ... Nature medicine 17 (9), 1142-1146, 2011 | 183 | 2011 |
Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4 C Del Fresno, K Otero, L Gómez-García, MC González-León, ... The Journal of Immunology 174 (5), 3032-3040, 2005 | 183 | 2005 |
Structure of the homodimeric androgen receptor ligand-binding domain M Nadal, S Prekovic, N Gallastegui, C Helsen, M Abella, K Zielinska, ... Nature communications 8 (1), 14388, 2017 | 181 | 2017 |
Structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug P Fuentes-Prior, C Noeske-Jungblut, P Donner, WD Schleuning, R Huber, ... Proceedings of the National Academy of Sciences 94 (22), 11845-11850, 1997 | 160 | 1997 |
Isolation, cloning and structural characterisation of boophilin, a multifunctional Kunitz-type proteinase inhibitor from the cattle tick S Macedo-Ribeiro, C Almeida, BM Calisto, T Friedrich, R Mentele, ... PLoS One 3 (2), e1624, 2008 | 153 | 2008 |
Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase R Friedrich, P Fuentes-Prior, E Ong, G Coombs, M Hunter, R Oehler, ... Journal of Biological Chemistry 277 (3), 2160-2168, 2002 | 146 | 2002 |
Tick-derived Kunitz-type inhibitors as antihemostatic factors MÁ Corral-Rodríguez, S Macedo-Ribeiro, PJB Pereira, P Fuentes-Prior Insect biochemistry and molecular biology 39 (9), 579-595, 2009 | 118 | 2009 |
Monocytes from cystic fibrosis patients are locked in an LPS tolerance state: down-regulation of TREM-1 as putative underlying mechanism C del Fresno, V Gomez-Pina, V Lores, A Soares-Schanoski, ... PloS one 3 (7), e2667, 2008 | 117 | 2008 |