Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods C Wu, Y Liu, Y Yang, P Zhang, W Zhong, Y Wang, Q Wang, Y Xu, M Li, ... Acta Pharmaceutica Sinica B 10 (5), 766-788, 2020 | 2178 | 2020 |
Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger J Liao, H Li, W Zeng, DB Sauer, R Belmares, Y Jiang Science 335 (6069), 686-690, 2012 | 274 | 2012 |
Furin: a potential therapeutic target for COVID-19 C Wu, M Zheng, Y Yang, X Gu, K Yang, M Li, Y Liu, Q Zhang, P Zhang, ... Iscience 23 (10), 101642, 2020 | 140 | 2020 |
Structural and biochemical studies of TIGAR (TP53-induced glycolysis and apoptosis regulator) H Li, G Jogl Journal of Biological Chemistry 284 (3), 1748-1754, 2009 | 134 | 2009 |
Phomopsterones A and B, Two Functionalized Ergostane-Type Steroids from the Endophytic Fungus Phomopsis sp. TJ507A Z Hu, Y Wu, S Xie, W Sun, Y Guo, XN Li, J Liu, H Li, J Wang, Z Luo, Y Xue, ... Organic letters 19 (1), 258-261, 2017 | 91 | 2017 |
Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2 W Li, M Zheng, S Wu, S Gao, M Yang, Z Li, Q Min, W Sun, L Chen, ... Journal of Experimental & Clinical Cancer Research 36 (1), 1-12, 2017 | 81 | 2017 |
Asperterpenes A and B, two unprecedented meroterpenoids from Aspergillus terreus with BACE1 inhibitory activities C Qi, J Bao, J Wang, H Zhu, Y Xue, X Wang, H Li, W Sun, W Gao, Y Lai, ... Chemical Science 7 (10), 6563-6572, 2016 | 77 | 2016 |
Crystal structure of the zinc-binding transport protein ZnuA from Escherichia coli reveals an unexpected variation in metal coordination H Li, G Jogl Journal of molecular biology 368 (5), 1358-1366, 2007 | 75 | 2007 |
Rational design and synthesis of novel dual PROTACs for simultaneous degradation of EGFR and PARP M Zheng, J Huo, X Gu, Y Wang, C Wu, Q Zhang, W Wang, Y Liu, Y Liu, ... Journal of Medicinal Chemistry 64 (11), 7839-7852, 2021 | 71 | 2021 |
Progress in the discovery of naturally occurring anti-diabetic drugs and in the identification of their molecular targets JH He, LX Chen, H Li Fitoterapia 134, 270-289, 2019 | 71 | 2019 |
Triterpenoids from Ganoderma lucidum and Their Potential Anti-inflammatory Effects YL Wu, F Han, SS Luan, R Ai, P Zhang, H Li, LX Chen Journal of agricultural and food chemistry 67 (18), 5147-5158, 2019 | 66 | 2019 |
Filicinic Acid Based Meroterpenoids with Anti-Epstein–Barr Virus Activities from Hypericum japonicum L Hu, Y Zhang, H Zhu, J Liu, H Li, XN Li, W Sun, J Zeng, Y Xue, Y Zhang Organic letters 18 (9), 2272-2275, 2016 | 64 | 2016 |
Pantoprazole, an FDA-approved proton-pump inhibitor, suppresses colorectal cancer growth by targeting T-cell-originated protein kinase X Zeng, L Liu, M Zheng, H Sun, J Xiao, T Lu, G Huang, P Chen, J Zhang, ... Oncotarget 7 (16), 22460, 2016 | 54 | 2016 |
New natural inhibitors of hexokinase 2 (HK2): Steroids from Ganoderma sinense F Bao, K Yang, C Wu, S Gao, P Wang, L Chen, H Li Fitoterapia 125, 123-129, 2018 | 51 | 2018 |
Anti-inflammatory Lathyrane Diterpenoids from Euphorbia lathyris CY Zhang, YL Wu, P Zhang, ZZ Chen, H Li, LX Chen Journal of natural products 82 (4), 756-764, 2019 | 47 | 2019 |
Effects of kinsenoside, a potential immunosuppressive drug for autoimmune hepatitis, on dendritic cells/CD8+T cells communication in mice M Xiang, T Liu, W Tan, H Ren, H Li, J Liu, H Cao, Q Cheng, X Liu, H Zhu, ... Hepatology 64 (6), 2135-2150, 2016 | 45 | 2016 |
Identification of mangiferin as a potential glucokinase activator by structure-based virtual ligand screening Q Min, X Cai, W Sun, F Gao, Z Li, Q Zhang, LS Wan, H Li, J Chen Scientific reports 7 (1), 44681, 2017 | 39 | 2017 |
Diterpenoids from the genus Euphorbia: Structure and biological activity (2013–2019) Y Xu, P Tang, M Zhu, Y Wang, D Sun, H Li, L Chen Phytochemistry 190, 112846, 2021 | 38 | 2021 |
Downregulation of SIRT6 by miR-34c-5p is associated with poor prognosis and promotes colon cancer proliferation through inhibiting apoptosis via the JAK2/STAT3 signaling pathway N Li, D Mao, Y Cao, H Li, F Ren, K Li International Journal of Oncology 52 (5), 1515-1527, 2018 | 38 | 2018 |
The dietary compound luteolin inhibits pancreatic cancer growth by targeting BCL-2 Z Li, Y Zhang, L Chen, H Li Food & function 9 (5), 3018-3027, 2018 | 38 | 2018 |