| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13278* | 2021 |
| Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences N Exner, AK Lutz, C Haass, KF Winklhofer The EMBO journal 31 (14), 3038-3062, 2012 | 696 | 2012 |
| Mitochondrial dysfunction in Parkinson's disease KF Winklhofer, C Haass Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1802 (1), 29-44, 2010 | 695 | 2010 |
| Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin N Exner, B Treske, D Paquet, K Holmström, C Schiesling, S Gispert, ... Journal of Neuroscience 27 (45), 12413-12418, 2007 | 622 | 2007 |
| Inhibition of mitochondrial fusion by α‐synuclein is rescued by PINK1, Parkin and DJ‐1 F Kamp, N Exner, AK Lutz, N Wender, J Hegermann, B Brunner, ... The EMBO journal 29 (20), 3571-3589, 2010 | 594 | 2010 |
| The two faces of protein misfolding: gain‐and loss‐of‐function in neurodegenerative diseases KF Winklhofer, J Tatzelt, C Haass The EMBO journal 27 (2), 336-349, 2008 | 492 | 2008 |
| Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation AK Lutz, N Exner, ME Fett, JS Schlehe, K Kloos, K Lämmermann, ... Journal of Biological Chemistry 284 (34), 22938-22951, 2009 | 465 | 2009 |
| Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics I Irrcher, H Aleyasin, EL Seifert, SJ Hewitt, S Chhabra, M Phillips, AK Lutz, ... Human molecular genetics 19 (19), 3734-3746, 2010 | 454 | 2010 |
| Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA AC Woerner, F Frottin, D Hornburg, LR Feng, F Meissner, M Patra, ... Science 351 (6269), 173-176, 2016 | 428 | 2016 |
| Propionic acid shapes the multiple sclerosis disease course by an immunomodulatory mechanism A Duscha, B Gisevius, S Hirschberg, N Yissachar, GI Stangl, E Dawin, ... Cell 180 (6), 1067-1080. e16, 2020 | 421 | 2020 |
| Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress L Bouman, A Schlierf, AK Lutz, J Shan, A Deinlein, J Kast, Z Galehdar, ... Cell Death & Differentiation 18 (5), 769-782, 2011 | 377 | 2011 |
| The cellular prion protein mediates neurotoxic signalling of β‐sheet‐rich conformers independent of prion replication UK Resenberger, A Harmeier, AC Woerner, JL Goodman, V Müller, ... The EMBO journal 30 (10), 2057-2070, 2011 | 281 | 2011 |
| Inflammation-induced alteration of astrocyte mitochondrial dynamics requires autophagy for mitochondrial network maintenance E Motori, J Puyal, N Toni, A Ghanem, C Angeloni, M Malaguti, ... Cell metabolism 18 (6), 844-859, 2013 | 250 | 2013 |
| Parkin mediates neuroprotection through activation of IκB kinase/nuclear factor-κB signaling IH Henn, L Bouman, JS Schlehe, A Schlierf, JE Schramm, E Wegener, ... Journal of Neuroscience 27 (8), 1868-1878, 2007 | 246 | 2007 |
| The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO AK Müller-Rischart, A Pilsl, P Beaudette, M Patra, K Hadian, M Funke, ... Molecular cell 49 (5), 908-921, 2013 | 230 | 2013 |
| Intracellular re‐routing of prion protein prevents propagation of PrPSc and delays onset of prion disease S Gilch, KF Winklhofer, MH Groschup, M Nunziante, R Lucassen, ... The EMBO journal, 2001 | 214 | 2001 |
| Inactivation of parkin by oxidative stress and C-terminal truncations: a protective role of molecular chaperones KF Winklhofer, IH Henn, PC Kay-Jackson, U Heller, J Tatzelt Journal of Biological Chemistry 278 (47), 47199-47208, 2003 | 174 | 2003 |
| Parkin and mitochondrial quality control: toward assembling the puzzle KF Winklhofer Trends in cell biology 24 (6), 332-341, 2014 | 169 | 2014 |
| The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity EK Butler, A Voigt, AK Lutz, JP Toegel, E Gerhardt, P Karsten, ... PLoS genetics 8 (2), e1002488, 2012 | 160 | 2012 |
| Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson’s disease A Pilsl, KF Winklhofer Acta neuropathologica 123, 173-188, 2012 | 155 | 2012 |
