Gut microbiota-involved mechanisms in enhancing systemic exposure of ginsenosides by coexisting polysaccharides in ginseng decoction SS Zhou, J Xu, H Zhu, J Wu, JD Xu, R Yan, XY Li, HH Liu, SM Duan, ... Scientific Reports 6 (1), 1-13, 2016 | 186 | 2016 |
Saikosaponin a and its epimer saikosaponin d exhibit anti-inflammatory activity by suppressing activation of NF-κB signaling pathway CN Lu, ZG Yuan, XL Zhang, R Yan, YQ Zhao, M Liao, JX Chen International immunopharmacology 14 (1), 121-126, 2012 | 185 | 2012 |
Enhanced topical penetration, system exposure and anti-psoriasis activity of two particle-sized, curcumin-loaded PLGA nanoparticles in hydrogel L Sun, Z Liu, L Wang, D Cun, HHY Tong, R Yan, X Chen, R Wang, ... Journal of Controlled Release 254, 44-54, 2017 | 170 | 2017 |
Pharmacokinetics and metabolism of ligustilide, a major bioactive component in Rhizoma Chuanxiong, in the rat R Yan, NL Ko, SL Li, YK Tam, G Lin Drug Metabolism and Disposition 36 (2), 400-408, 2008 | 159 | 2008 |
Simultaneous analysis of seventeen chemical ingredients of Ligusticum chuanxiong by on-line high performance liquid chromatography-diode array detector-mass spectrometry SL Li, SSK Chan, G Lin, L Ling, R Yan, HS Chung, YK Tam Planta medica 69 (05), 445-451, 2003 | 139 | 2003 |
Simultaneous quantification of 12 bioactive components of Ligusticum chuanxiong Hort. by high-performance liquid chromatography R Yan, SL Li, HS Chung, YK Tam, G Lin Journal of Pharmaceutical and Biomedical Analysis 37 (1), 87-95, 2005 | 129 | 2005 |
α-Glucosidase inhibitory effect and simultaneous quantification of three major flavonoid glycosides in Microctis folium YG Chen, P Li, P Li, R Yan, XQ Zhang, Y Wang, XT Zhang, WC Ye, ... Molecules 18 (4), 4221-4232, 2013 | 93 | 2013 |
Particle size effect of curcumin nanosuspensions on cytotoxicity, cellular internalization, in vivo pharmacokinetics and biodistribution C Bi, XQ Miao, SF Chow, WJ Wu, R Yan, YH Liao, AHL Chow, Y Zheng Nanomedicine: Nanotechnology, Biology and Medicine 13 (3), 943-953, 2017 | 92 | 2017 |
Ginseng polysaccharides enhanced ginsenoside Rb1 and microbial metabolites exposure through enhancing intestinal absorption and affecting gut microbial metabolism H Shen, XJ Gao, T Li, WH Jing, BL Han, YM Jia, N Hu, ZX Yan, SL Li, ... Journal of ethnopharmacology 216, 47-56, 2018 | 87 | 2018 |
Characterization of Metabolism and in Vitro Permeability Study of Notoginsenoside R1 from Radix Notoginseng JQ Ruan, WI Leong, R Yan, YT Wang Journal of agricultural and food chemistry 58 (9), 5770-5776, 2010 | 71 | 2010 |
Pharmacokinetic evidence on contribution of intestinal bacterial conversion to beneficial effects of astragaloside IV, a marker compound of Astragali Radix, in traditional oral … RN Zhou, YL Song, JQ Ruan, YT Wang, R Yan Drug metabolism and pharmacokinetics, DMPK-11-RG-160, 2012 | 68 | 2012 |
Post-Harvest Alteration of the Main Chemical Ingredients in Ligusticum chuanxiong HORT. (Rhizoma Chuanxiong) SL Li, R Yan, YK Tam, G Lin Chemical and Pharmaceutical Bulletin 55 (1), 140-144, 2007 | 68 | 2007 |
Pharmacokinetics of anthraquinones in rat plasma after oral administration of a rhubarb extract W Wu, R Yan, M Yao, Y Zhan, Y Wang Biomedical Chromatography 28 (4), 564-572, 2014 | 65 | 2014 |
Influence of sulphur-fumigation on the quality of white ginseng: A quantitative evaluation of major ginsenosides by high performance liquid chromatography X Jin, LY Zhu, H Shen, J Xu, SL Li, XB Jia, H Cai, BC Cai, R Yan Food chemistry 135 (3), 1141-1147, 2012 | 61 | 2012 |
Astilbin selectively facilitates the apoptosis of interleukin-2-dependent phytohemagglutinin-activated Jurkat cells R Yan, Q Xu Pharmacological Research 44 (2), 135-139, 2001 | 59 | 2001 |
In Vitro Pharmacokinetic Characterization of Mulberroside A, the Main Polyhydroxylated Stilbene in Mulberry (Morus alba L.), and Its Bacterial Metabolite … M Mei, JQ Ruan, WJ Wu, RN Zhou, JPC Lei, HY Zhao, R Yan, YT Wang Journal of agricultural and food chemistry 60 (9), 2299-2308, 2012 | 58 | 2012 |
In vitro glucuronidation of five rhubarb anthraquinones by intestinal and liver microsomes from humans and rats W Wu, N Hu, Q Zhang, Y Li, P Li, R Yan, Y Wang Chemico-biological interactions 219, 18-27, 2014 | 57 | 2014 |
Computer-aided formulation design for a highly soluble lutein–cyclodextrin multiple-component delivery system Q Zhao, N Miriyala, Y Su, W Chen, X Gao, L Shao, R Yan, H Li, X Yao, ... Molecular Pharmaceutics 15 (4), 1664-1673, 2018 | 56 | 2018 |
Qualitative analysis and enantiospecific determination of angular-type pyranocoumarins in Peucedani Radix using achiral and chiral liquid chromatography coupled with tandem … YL Song, WH Jing, G Du, FQ Yang, R Yan, YT Wang Journal of Chromatography A 1338, 24-37, 2014 | 55 | 2014 |
Enantioseparation and absolute configuration determination of angular-type pyranocoumarins from peucedani radix using enzymatic hydrolysis and chiral HPLC-MS/MS analysis YL Song, QW Zhang, YP Li, R Yan, YT Wang Molecules 17 (4), 4236-4251, 2012 | 52 | 2012 |