Crystal structures of the M1 and M4 muscarinic acetylcholine receptors DM Thal, B Sun, D Feng, V Nawaratne, K Leach, CC Felder, MG Bures, ... Nature 531 (7594), 335-340, 2016 | 351 | 2016 |
New insights into the function of M4 muscarinic acetylcholine receptors gained using a novel allosteric modulator and a DREADD (designer receptor exclusively activated by a … V Nawaratne, K Leach, N Suratman, RE Loiacono, CC Felder, ... Molecular pharmacology 74 (4), 1119-1131, 2008 | 136 | 2008 |
Structural determinants of allosteric agonism and modulation at the M4 muscarinic acetylcholine receptor: identification of ligand-specific and global activation mechanisms V Nawaratne, K Leach, CC Felder, PM Sexton, A Christopoulos Journal of Biological Chemistry 285 (25), 19012-19021, 2010 | 84 | 2010 |
Kinase dead BTK mutations confer resistance to covalent and noncovalent BTK inhibitors but are susceptible to clinical stage BTK degraders S Montoya, J Bourcier, MC Thompson, M Noviski, M Tan, E Wang, X Mi, ... Blood 140 (Supplement 1), 1811-1813, 2022 | 16 | 2022 |
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics Z Vuckovic, J Wang, V Pham, JI Mobbs, MJ Belousoff, A Bhattarai, ... Elife 12, e83477, 2023 | 14 | 2023 |
The conserved MASRPF motif in the Attractin homolog, Distracted, is required for association with Drosophila E3-ligase Mgrn1 V Nawaratne, S Kudumala, PP Kakad, TA Godenschwege microPublication Biology 2021, 2021 | 3 | 2021 |
Prolonged Amphetamine Exposures Increase the Endogenous Human Dopamine Receptors 2 at the Cellular Membrane in Cells Lacking the Dopamine Transporter V Nawaratne, SP McLaughlin, FP Mayer, Z Gichi, A Mastriano, L Carvelli Frontiers in Cellular Neuroscience 15, 681539, 2021 | 1 | 2021 |
Structure-function studies of M4 muscarinic acetylcholine receptor allosteric modulation OV Nawaratne Monash University, 2011 | | 2011 |