Gating interaction maps reveal a noncanonical electromechanical coupling mode in the Shaker K+ channel AI Fernández-Mariño, TJ Harpole, K Oelstrom, L Delemotte, B Chanda Nature structural & molecular biology 25 (4), 320-326, 2018 | 69 | 2018 |
Structure of the Shaker Kv channel and mechanism of slow C-type inactivation XF Tan, C Bae, R Stix, AI Fernández-Mariño, K Huffer, TH Chang, J Jiang, ... Science advances 8 (11), eabm7814, 2022 | 56 | 2022 |
Structures of the T cell potassium channel Kv1. 3 with immunoglobulin modulators P Selvakumar, AI Fernández-Mariño, N Khanra, C He, AJ Paquette, ... Nature Communications 13 (1), 3854, 2022 | 38 | 2022 |
RING1B contributes to Ewing sarcoma development by repressing the NaV1. 6 sodium channel and the NF-κB pathway, independently of the fusion oncoprotein I Hernandez-Muñoz, E Figuerola, S Sanchez-Molina, E Rodriguez, ... Oncotarget 7 (29), 46283, 2016 | 14 | 2016 |
Tungstate activates BK channels in a β subunit- and Mg2+-dependent manner: relevance for arterial vasodilatation AI Fernandez-Marino, C Porras-Gonzalez, P González-Rodríguez, ... Cardiovascular research 95 (1), 29-38, 2012 | 13 | 2012 |
Tungstate-Targeting of BKαβ1 Channels Tunes ERK Phosphorylation and Cell Proliferation in Human Vascular Smooth Muscle AI Fernández-Mariño, P Cidad, D Zafra, L Nocito, J Dominguez, ... PLoS One 10 (2), e0118148, 2015 | 11 | 2015 |
Inactivation of the Kv2. 1 channel through electromechanical coupling AI Fernández-Mariño, XF Tan, C Bae, K Huffer, J Jiang, KJ Swartz Nature 622 (7982), 410-417, 2023 | 10 | 2023 |
BK channel activation by tungstate requires the β1 subunit extracellular loop residues essential to modulate voltage sensor function and channel gating AI Fernández-Mariño, MA Valverde, JM Fernández-Fernández Pflügers Archiv-European Journal of Physiology 466, 1365-1375, 2014 | 9 | 2014 |
Eukaryotic Kv channel Shaker inactivates through selectivity filter dilation rather than collapse R Stix, XF Tan, C Bae, AI Fernández-Mariño, KJ Swartz, ... Science Advances 9 (49), eadj5539, 2023 | 3 | 2023 |
Dilation of ion selectivity filters in cation channels K Huffer, XF Tan, AI Fernández-Mariño, S Dhingra, KJ Swartz Trends in Biochemical Sciences, 2024 | 1 | 2024 |
Cryo-EM structure of the mammalian Kv2. 1 delayed-rectifier potassium channel reveals insight into gating mechanisms and epileptic encephalopathy AI Fernández-Mariño, X Tan, C Bae, R Stix, TH Chang, J Jiang, ... Biophysical Journal 121 (3), 295a, 2022 | 1 | 2022 |
Promoting a MOSAIC future in science R Banerjee, KF Block Trends in Biochemical Sciences, 2024 | | 2024 |
Structural basis for regulation of Kv2. 1 by PIP2 X Tan, AI Fernández-Mariño, C Bae, K Swartz Biophysical Journal 123 (3), 527a, 2024 | | 2024 |
Molecular mechanism of Kv1. 3 inactivation: Insights from nanobody binding and mutational analysis P Selvakumar, AI Fernández-Mariño, JR Meyerson, K Swartz Biophysical Journal 123 (3), 251a, 2024 | | 2024 |
Structures of the Kv2. 1 channel and mechanism of inactivation through electromechanical coupling A Fernandez-Mariño, X Tan, C Bae, K Huffer, J Jiang, K Swartz Biophysical Journal 123 (3), 6a, 2024 | | 2024 |
Cryo-EM structure of the mammalian Kv2. 1 channel and epileptic encephalopathy mutations provide insight into electromechanical coupling and slow inactivation AI Fernández-Mariño, X Tan, C Bae, KJ Swartz Biophysical Journal 122 (3), 385a, 2023 | | 2023 |
Inactivation mechanism of an immunoglobulin modulator of the T-cell potassium channel Kv1. 3 P Selvakumar, AI Fernández-Mariño, B Wang, WJ Rice, JR Meyerson, ... Biophysical Journal 122 (3), 13a-14a, 2023 | | 2023 |
Non canonical VSD-pore conections A Fernandez-Mariño MDPI, 2021 | | 2021 |
Conserved Voltage-Dependent Gating Elements between Shaker and HERG Kv Channels AI Fernández-Mariño, K Swartz Biophysical Journal 118 (3), 332a, 2020 | | 2020 |
Identifying Common Structural Features for Electromechanical Coupling between Domain-Swapped and Non-Domain Swapped Potassium Channels AI Fernández-Mariño, KJ Swartz Biophysical Journal 116 (3), 541a, 2019 | | 2019 |