CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance T Koga, CM Hedrich, M Mizui, N Yoshida, K Otomo, LA Lieberman, ... The Journal of clinical investigation 124 (5), 2234-2245, 2014 | 207 | 2014 |
IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4− CD8− IL-17–producing T cells M Mizui, T Koga, LA Lieberman, J Beltran, N Yoshida, MC Johnson, ... The Journal of Immunology 193 (5), 2168-2177, 2014 | 121 | 2014 |
Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells M Kono, N Yoshida, K Maeda, GC Tsokos Proceedings of the National Academy of Sciences 115 (10), 2478-2483, 2018 | 100 | 2018 |
CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease K Maeda, K Otomo, N Yoshida, MS Abu-Asab, K Ichinose, T Nishino, ... The Journal of clinical investigation 128 (8), 3445-3459, 2018 | 92 | 2018 |
Glutaminase 1 Inhibition Reduces Glycolysis and Ameliorates Lupus‐like Disease in MRL/lpr Mice and Experimental Autoimmune Encephalomyelitis M Kono, N Yoshida, K Maeda, A Suárez‐Fueyo, VC Kyttaris, GC Tsokos Arthritis & Rheumatology 71 (11), 1869-1878, 2019 | 91 | 2019 |
Pyruvate kinase M2 is requisite for Th1 and Th17 differentiation M Kono, K Maeda, I Stocton-Gavanescu, W Pan, M Umeda, E Katsuyama, ... JCI insight 4 (12), 2019 | 91 | 2019 |
ICER is requisite for Th17 differentiation N Yoshida, D Comte, M Mizui, K Otomo, F Rosetti, TN Mayadas, ... Nature communications 7 (1), 12993, 2016 | 84 | 2016 |
Antiarrhythmic properties of tedisamil (KC8857), a putative transient outward K+ current blocker. GN Beatch, S Abraham, BA MacLeod, NR Yoshida, MJ Walker British journal of pharmacology 102 (1), 13, 1991 | 79 | 1991 |
KN-93, an inhibitor of calcium/calmodulin-dependent protein kinase IV, promotes generation and function of Foxp3+ regulatory T cells in MRL/lpr mice T Koga, M Mizui, N Yoshida, K Otomo, LA Lieberman, JC Crispín, ... Autoimmunity 47 (7), 445-450, 2014 | 67 | 2014 |
Pyruvate dehydrogenase phosphatase catalytic subunit 2 limits Th17 differentiation M Kono, N Yoshida, K Maeda, NE Skinner, W Pan, VC Kyttaris, ... Proceedings of the National Academy of Sciences 115 (37), 9288-9293, 2018 | 65 | 2018 |
Signaling lymphocytic activation molecule family member 7 engagement restores defective effector CD8+ T cell function in systemic lupus erythematosus D Comte, MP Karampetsou, N Yoshida, K Kis‐Toth, VC Kyttaris, ... Arthritis & rheumatology 69 (5), 1035-1044, 2017 | 64 | 2017 |
Cutting edge: nanogel-based delivery of an inhibitor of CaMK4 to CD4+ T cells suppresses experimental autoimmune encephalomyelitis and lupus-like disease in mice K Otomo, T Koga, M Mizui, N Yoshida, C Kriegel, S Bickerton, TM Fahmy, ... The Journal of Immunology 195 (12), 5533-5537, 2015 | 64 | 2015 |
Brief Report: CD4+ T Cells From Patients With Systemic Lupus Erythematosus Respond Poorly to Exogenous Interleukin‐2 D Comte, MP Karampetsou, K Kis‐Toth, N Yoshida, SJ Bradley, ... Arthritis & rheumatology 69 (4), 808-813, 2017 | 58 | 2017 |
Calcium/Calmodulin‐Dependent Kinase IV Facilitates the Recruitment of Interleukin‐17–Producing Cells to Target Organs Through the CCR6/CCL20 Axis in Th17 Cell–Driven … T Koga, K Otomo, M Mizui, N Yoshida, M Umeda, K Ichinose, A Kawakami, ... Arthritis & rheumatology 68 (8), 1981-1988, 2016 | 40 | 2016 |
CXCR4 expression on activated B cells is downregulated by CD63 and IL-21 N Yoshida, D Kitayama, M Arima, A Sakamoto, A Inamine, ... The Journal of Immunology 186 (5), 2800-2808, 2011 | 40 | 2011 |
Engagement of SLAMF3 enhances CD4+ T-cell sensitivity to IL-2 and favors regulatory T-cell polarization in systemic lupus erythematosus D Comte, MP Karampetsou, K Kis-Toth, N Yoshida, SJ Bradley, M Mizui, ... Proceedings of the National Academy of Sciences 113 (33), 9321-9326, 2016 | 39 | 2016 |
Downregulation of miR-200a-3p, targeting CtBP2 complex, is involved in the hypoproduction of IL-2 in systemic lupus erythematosus–derived T cells E Katsuyama, M Yan, KS Watanabe, S Matsushima, Y Yamamura, ... The Journal of Immunology 198 (11), 4268-4276, 2017 | 38 | 2017 |
Pin1‐targeted therapy for systemic lupus erythematosus S Wei, N Yoshida, G Finn, S Kozono, M Nechama, VC Kyttaris, ... Arthritis & Rheumatology 68 (10), 2503-2513, 2016 | 32 | 2016 |
The regulatory subunit PPP2R2A of PP2A enhances Th1 and Th17 differentiation through activation of the GEF-H1/RhoA/ROCK signaling pathway W Pan, K Nagpal, A Suárez-Fueyo, A Ferretti, N Yoshida, MG Tsokos, ... The Journal of Immunology 206 (8), 1719-1728, 2021 | 31 | 2021 |
STAT4 single nucleotide polymorphism, rs7574865 G/T, as a risk for antiphospholipid syndrome T Horita, T Atsumi, N Yoshida, H Nakagawa, H Kataoka, S Yasuda, ... Annals of the rheumatic diseases 68 (8), 1366-1367, 2009 | 28 | 2009 |