Deviant ryanodine receptor-mediated calcium release resets synaptic homeostasis in presymptomatic 3xTg-AD mice S Chakroborty, I Goussakov, MB Miller, GE Stutzmann Journal of Neuroscience 29 (30), 9458-9470, 2009 | 223 | 2009 |
Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer’s disease-like pathologies and cognitive deficits A Lacampagne, X Liu, S Reiken, R Bussiere, AC Meli, I Lauritzen, ... Acta neuropathologica 134, 749-767, 2017 | 158 | 2017 |
Stabilizing ER Ca2+ Channel Function as an Early Preventative Strategy for Alzheimer’s Disease S Chakroborty, C Briggs, MB Miller, I Goussakov, C Schneider, J Kim, ... PloS one 7 (12), e52056, 2012 | 148 | 2012 |
Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer's disease mice S Chakroborty, J Kim, C Schneider, C Jacobson, J Molgó, GE Stutzmann Journal of Neuroscience 32 (24), 8341-8353, 2012 | 145 | 2012 |
Calcium channelopathies and Alzheimer's disease: insight into therapeutic success and failures S Chakroborty, GE Stutzmann European journal of pharmacology 739, 83-95, 2014 | 111 | 2014 |
Phosphodiesterase 10A inhibition improves cortico-basal ganglia function in Huntington’s disease models V Beaumont, S Zhong, H Lin, WJ Xu, A Bradaia, E Steidl, M Gleyzes, ... Neuron 92 (6), 1220-1237, 2016 | 104 | 2016 |
Nitric oxide signaling is recruited as a compensatory mechanism for sustaining synaptic plasticity in Alzheimer's disease mice S Chakroborty, J Kim, C Schneider, AR West, GE Stutzmann Journal of Neuroscience 35 (17), 6893-6902, 2015 | 102 | 2015 |
Emerging pathways driving early synaptic pathology in Alzheimer's disease CA Briggs, S Chakroborty, GE Stutzmann Biochemical and biophysical research communications 483 (4), 988-997, 2017 | 101 | 2017 |
Early calcium dysregulation in Alzheimer’s disease: setting the stage for synaptic dysfunction S Chakroborty, GE Stutzmann Science China Life Sciences 54, 752-762, 2011 | 78 | 2011 |
Reduced presynaptic vesicle stores mediate cellular and network plasticity defects in an early-stage mouse model of Alzheimer’s disease S Chakroborty, ES Hill, DT Christian, R Helfrich, S Riley, C Schneider, ... Molecular Neurodegeneration 14, 1-21, 2019 | 61 | 2019 |
Facilitation of corticostriatal transmission following pharmacological inhibition of striatal phosphodiesterase 10A: role of nitric oxide-soluble guanylyl cyclase-cGMP … FE Padovan-Neto, S Sammut, S Chakroborty, AM Dec, S Threlfell, ... Journal of Neuroscience 35 (14), 5781-5791, 2015 | 49 | 2015 |
Generation of dendritic Ca2+ oscillations as a consequence of altered ryanodine receptor function in AD neurons I Goussakov, S Chakroborty, GE Stutzmann Channels 5 (1), 9-13, 2011 | 24 | 2011 |
Impact of vortioxetine on synaptic integration in prefrontal-subcortical circuits: comparisons with escitalopram S Chakroborty, TR Geisbush, E Dale, AL Pehrson, C Sánchez, AR West Frontiers in Pharmacology 8, 764, 2017 | 10 | 2017 |
Phosphodiesterase 9A inhibition facilitates corticostriatal transmission in wild-type and transgenic rats that model Huntington’s disease S Chakroborty, FP Manfredsson, AM Dec, PW Campbell, GE Stutzmann, ... Frontiers in neuroscience 14, 466, 2020 | 7 | 2020 |
AlzPED: Improving the predictive power and translational validity of preclinical testing of candidate therapeutics in Alzheimer’s disease animal models: Development of new … S Chakroborty, A Sharma, K Mancevska, Z Martin, J Yuan, C Sheffield, ... Alzheimer's & Dementia 16, e036763, 2020 | 2 | 2020 |
Alzheimer research forum live discussion: Calcium in AD pathogenesis C Atwood, B Bacskai, K Kuchibhotla, I Bezprozvanny, S Chakroborty, ... Journal of Alzheimer's Disease 16 (4), 909-917, 2009 | 2 | 2009 |
Alzheimer’s Disease Preclinical Efficacy Database (AlzPED): Optimizing the Scientific Rigor and Reproducibility of Preclinical Research in Alzheimer’s Disease S Chakroborty, Z Martin, J Yuan, SS Petanceska, LM Refolo Alzheimer's & Dementia 18, e062566, 2022 | 1 | 2022 |
AlzPED: An Open Science Tool to Increase Rigor in Therapeutic Efficacy Testing in Alzheimer's Animal Models S Chakroborty, J Viswanathan, MFL Gallofre, Z Martin, SS Petanceska, ... Alzheimer's Association International Conference, 2024 | | 2024 |
AlzPED: Raising the Standards for Preclinical Efficacy Testing of Candidate Therapeutics in Alzheimer’s Disease S Chakroborty, J Viswanathan, MFL Gallofre, Z Martin, SS Petanceska, ... Alzheimer's Association International Conference, 2023 | | 2023 |
AlzPED: Optimizing the predictive power of drug efficacy studies in Alzheimer’s disease animal models S Chakroborty, A Sharma, Z Martin, J Yuan, SS Petanceska, LM Refolo Alzheimer's & Dementia 17, e054045, 2021 | | 2021 |