Spirocyclic scaffolds in medicinal chemistry K Hiesinger, D Dar’in, E Proschak, M Krasavin Journal of Medicinal Chemistry 64 (1), 150-183, 2020 | 369 | 2020 |
Antimalarial, antiproliferative, and antitumor activities of artemisinin-derived, chemically robust, trioxane dimers GH Posner, P Ploypradith, MH Parker, H O'Dowd, SH Woo, J Northrop, ... Journal of medicinal chemistry 42 (21), 4275-4280, 1999 | 192 | 1999 |
Spirocyclic motifs in natural products E Chupakhin, O Babich, A Prosekov, L Asyakina, M Krasavin Molecules 24 (22), 4165, 2019 | 174 | 2019 |
Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and … G Papeo, H Posteri, D Borghi, AA Busel, F Caprera, E Casale, M Ciomei, ... Journal of medicinal chemistry 58 (17), 6875-6898, 2015 | 126 | 2015 |
Multi-component reactions between 2-aminopyrimidine, aldehydes and isonitriles: the use of a nonpolar solvent suppresses formation of multiple products VZ Parchinsky, O Shuvalova, O Ushakova, DV Kravchenko, M Krasavin Tetrahedron letters 47 (6), 947-951, 2006 | 99 | 2006 |
Multicomponent reactions of isocyanides in the synthesis of heterocycles AV Ivachtchenko, YA Ivanenkov, VM Kysil, MY Krasavin, AP Ilyin Russian Chemical Reviews 79 (9), 787, 2010 | 95 | 2010 |
Complexity-Enhancing Acid-Promoted Rearrangement of Tricyclic Products of Tandem Ugi 4CC/Intramolecular Diels− Alder Reaction A Ilyin, V Kysil, M Krasavin, I Kurashvili, AV Ivachtchenko The Journal of Organic Chemistry 71 (25), 9544-9547, 2006 | 95 | 2006 |
Modern Trends of Organic Chemistry in Russian Universities AI Konovalov, IS Antipin, VA Burilov, TI Madzhidov, AR Kurbangalieva, ... Russian Journal of Organic Chemistry 54, 157-371, 2018 | 88 | 2018 |
Continued exploration of 1, 2, 4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX … M Krasavin, A Shetnev, T Sharonova, S Baykov, S Kalinin, A Nocentini, ... European Journal of Medicinal Chemistry 164, 92-105, 2019 | 82 | 2019 |
Current diversity of cyclic anhydrides for the Castagnoli–Cushman-type formal cycloaddition reactions: Prospects and challenges M Krasavin, D Dar’in Tetrahedron Letters 57 (15), 1635-1640, 2016 | 78 | 2016 |
New heterocyclic product space for the Castagnoli–Cushman three-component reaction D Dar’in, O Bakulina, M Chizhova, M Krasavin Organic letters 17 (15), 3930-3933, 2015 | 77 | 2015 |
Imidazo[1,2-a]quinoxalines Accessed via Two Sequential Isocyanide-Based Multicomponent Reactions M Krasavin, S Shkavrov, V Parchinsky, K Bukhryakov The Journal of Organic Chemistry 74 (6), 2627-2629, 2009 | 73 | 2009 |
Antimalarial simplified 3-aryltrioxanes: Synthesis and preclinical efficacy/toxicity testing in rodents GH Posner, HB Jeon, MH Parker, M Krasavin, IH Paik, TA Shapiro Journal of medicinal chemistry 44 (19), 3054-3058, 2001 | 72 | 2001 |
Heterocyclic periphery in the design of carbonic anhydrase inhibitors: 1, 2, 4-Oxadiazol-5-yl benzenesulfonamides as potent and selective inhibitors of cytosolic hCA II and … M Krasavin, A Shetnev, T Sharonova, S Baykov, T Tuccinardi, S Kalinin, ... Bioorganic Chemistry 76, 88-97, 2018 | 63 | 2018 |
Probing the ‘bipolar’nature of the carbonic anhydrase active site: Aromatic sulfonamides containing 1, 3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II … M Krasavin, M Korsakov, M Dorogov, T Tuccinardi, N Dedeoglu, ... European journal of medicinal chemistry 101, 334-347, 2015 | 62 | 2015 |
One-step assembly of carbamoyl-substituted heteroannelated [1, 4] thiazepines AP Ilyn, MV Loseva, VY Vvedensky, EB Putsykina, SE Tkachenko, ... The Journal of Organic Chemistry 71 (7), 2811-2819, 2006 | 62 | 2006 |
Mechanism of generation of closo-decaborato amidrazones. Intramolecular non-covalent B–H⋯ π (Ph) interaction determines stabilization of the configuration around the amidrazone … VK Burianova, DS Bolotin, AS Mikherdov, AS Novikov, PP Mokolokolo, ... New Journal of Chemistry 42 (11), 8693-8703, 2018 | 60 | 2018 |
A ‘sulfonyl-azide-free’(SAFE) aqueous-phase diazo transfer reaction for parallel and diversity-oriented synthesis D Dar’in, G Kantin, M Krasavin Chemical Communications 55 (36), 5239-5242, 2019 | 59 | 2019 |
1, 2, 4-oxadiazole/2-imidazoline hybrids: multi-target-directed compounds for the treatment of infectious diseases and cancer A Shetnev, S Baykov, S Kalinin, A Belova, V Sharoyko, A Rozhkov, ... International Journal of Molecular Sciences 20 (7), 1699, 2019 | 54 | 2019 |
Biologically active compounds based on the privileged 2-imidazoline scaffold: The world beyond adrenergic/imidazoline receptor modulators M Krasavin European Journal of Medicinal Chemistry 97, 525-537, 2015 | 54 | 2015 |