| Automated structure-and sequence-based design of proteins for high bacterial expression and stability A Goldenzweig, M Goldsmith, SE Hill, O Gertman, P Laurino, Y Ashani, ... Molecular cell 63 (2), 337-346, 2016 | 492 | 2016 |
| Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis SD Khare, Y Kipnis, PJ Greisen, R Takeuchi, Y Ashani, M Goldsmith, ... Nature chemical biology 8 (3), 294-300, 2012 | 253 | 2012 |
| Directed evolution of hydrolases for prevention of G-type nerve agent intoxication RD Gupta, M Goldsmith, Y Ashani, Y Simo, G Mullokandov, H Bar, ... Nature Chemical Biology 7 (2), 120-125, 2011 | 228 | 2011 |
| Quantitative analysis of translesion DNA synthesis across a benzo [a] pyrene-guanine adduct in mammalian cells: the role of DNA polymerase κ S Avkin, M Goldsmith, S Velasco-Miguel, N Geacintov, EC Friedberg, ... Journal of Biological Chemistry 279 (51), 53298-53305, 2004 | 219 | 2004 |
| Automated design of efficient and functionally diverse enzyme repertoires O Khersonsky, R Lipsh, Z Avizemer, Y Ashani, M Goldsmith, H Leader, ... Molecular cell 72 (1), 178-186. e5, 2018 | 213 | 2018 |
| Directed enzyme evolution: beyond the low-hanging fruit M Goldsmith, DS Tawfik Current opinion in structural biology 22 (4), 406-412, 2012 | 212 | 2012 |
| Design and in vitro realization of carbon-conserving photorespiration DL Trudeau, C Edlich-Muth, J Zarzycki, M Scheffen, M Goldsmith, ... Proceedings of the National Academy of Sciences 115 (49), E11455-E11464, 2018 | 135 | 2018 |
| Enzyme engineering: reaching the maximal catalytic efficiency peak M Goldsmith, DS Tawfik Current opinion in structural biology 47, 140-150, 2017 | 121 | 2017 |
| Evolved stereoselective hydrolases for broad-spectrum G-type nerve agent detoxification M Goldsmith, Y Ashani, Y Simo, M Ben-David, H Leader, I Silman, ... Chemistry & biology 19 (4), 456-466, 2012 | 108 | 2012 |
| Enzyme engineering by targeted libraries M Goldsmith, DS Tawfik Methods in enzymology 523, 257-283, 2013 | 94 | 2013 |
| Potential role of phenotypic mutations in the evolution of protein expression and stability M Goldsmith, DS Tawfik Proceedings of the National Academy of Sciences 106 (15), 6197-6202, 2009 | 93 | 2009 |
| Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers M Goldsmith, N Aggarwal, Y Ashani, H Jubran, PJ Greisen, S Ovchinnikov, ... Protein Engineering, Design and Selection 30 (4), 333-345, 2017 | 74 | 2017 |
| Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro F Worek, T Seeger, M Goldsmith, Y Ashani, H Leader, JS Sussman, ... Archives of toxicology 88, 1257-1266, 2014 | 64 | 2014 |
| Plasmid-encoded MucB protein is a DNA polymerase (pol RI) specialized for lesion bypass in the presence of MucA′, RecA, and SSB M Goldsmith, L Sarov-Blat, Z Livneh Proceedings of the National Academy of Sciences 97 (21), 11227-11231, 2000 | 64 | 2000 |
| Post-exposure treatment of VX poisoned guinea pigs with the engineered phosphotriesterase mutant C23: a proof-of-concept study F Worek, T Seeger, G Reiter, M Goldsmith, Y Ashani, H Leader, ... Toxicology Letters 231 (1), 45-54, 2014 | 59 | 2014 |
| Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro M Goldsmith, S Eckstein, Y Ashani, P Greisen, H Leader, JL Sussman, ... Archives of toxicology 90, 2711-2724, 2016 | 54 | 2016 |
| Avoiding and controlling double transformation artifacts M Goldsmith, C Kiss, ARM Bradbury, DS Tawfik Protein Engineering, Design & Selection 20 (7), 315-318, 2007 | 52 | 2007 |
| Stereo-specific synthesis of analogs of nerve agents and their utilization for selection and characterization of paraoxonase (PON1) catalytic scavengers Y Ashani, RD Gupta, M Goldsmith, I Silman, JL Sussman, DS Tawfik, ... Chemico-biological interactions 187 (1-3), 362-369, 2010 | 45 | 2010 |
| Catalytic bioscavengers as countermeasures against organophosphate nerve agents M Goldsmith, Y Ashani Chemico-biological interactions 292, 50-64, 2018 | 40 | 2018 |
| Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: intraosseous versus intravenous injection T Wille, K Neumaier, M Koller, C Ehinger, N Aggarwal, Y Ashani, ... Toxicology Letters 258, 198-206, 2016 | 34 | 2016 |
