| Advances in laboratory evolution of enzymes S Bershtein, DS Tawfik Current opinion in chemical biology 12 (2), 151-158, 2008 | 304 | 2008 |
| Intense neutral drifts yield robust and evolvable consensus proteins S Bershtein, K Goldin, DS Tawfik Journal of molecular biology 379 (5), 1029-1044, 2008 | 302 | 2008 |
| Protein quality control acts on folding intermediates to shape the effects of mutations on organismal fitness S Bershtein, W Mu, AWR Serohijos, J Zhou, EI Shakhnovich Molecular cell 49 (1), 133-144, 2013 | 185 | 2013 |
| Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes AC Palmer, E Toprak, M Baym, S Kim, A Veres, S Bershtein, R Kishony Nature communications 6 (1), 7385, 2015 | 156 | 2015 |
| Biophysical principles predict fitness landscapes of drug resistance JV Rodrigues, S Bershtein, A Li, ER Lozovsky, DL Hartl, EI Shakhnovich Proceedings of the National Academy of Sciences 113 (11), E1470-E1478, 2016 | 136 | 2016 |
| Soluble oligomerization provides a beneficial fitness effect on destabilizing mutations S Bershtein, W Mu, EI Shakhnovich Proceedings of the National Academy of Sciences 109 (13), 4857-4862, 2012 | 113 | 2012 |
| Ohno's model revisited: measuring the frequency of potentially adaptive mutations under various mutational drifts S Bershtein, DS Tawfik Molecular biology and evolution 25 (11), 2311-2318, 2008 | 88 | 2008 |
| Protein homeostasis imposes a barrier on functional integration of horizontally transferred genes in bacteria S Bershtein, AWR Serohijos, S Bhattacharyya, M Manhart, JM Choi, W Mu, ... PLoS genetics 11 (10), e1005612, 2015 | 82 | 2015 |
| Bridging the physical scales in evolutionary biology: from protein sequence space to fitness of organisms and populations S Bershtein, AWR Serohijos, EI Shakhnovich Current opinion in structural biology 42, 31-40, 2017 | 73 | 2017 |
| Transient protein-protein interactions perturb E. coli metabolome and cause gene dosage toxicity S Bhattacharyya, S Bershtein, J Yan, T Argun, AI Gilson, SA Trauger, ... elife 5, e20309, 2016 | 63 | 2016 |
| Chromosomal barcoding of E. coli populations reveals lineage diversity dynamics at high resolution W Jasinska, M Manhart, J Lerner, L Gauthier, AWR Serohijos, S Bershtein Nature ecology & evolution 4 (3), 437-452, 2020 | 40 | 2020 |
| Systems-level response to point mutations in a core metabolic enzyme modulates genotype-phenotype relationship S Bershtein, JM Choi, S Bhattacharyya, B Budnik, E Shakhnovich Cell reports 11 (4), 645-656, 2015 | 38 | 2015 |
| The interdimeric interface controls function and stability of Ureaplasma urealiticum methionine S-adenosyltransferase D Kleiner, F Shmulevich, R Zarivach, A Shahar, M Sharon, G Ben-Nissan, ... Journal of molecular biology 431 (24), 4796-4816, 2019 | 14 | 2019 |
| Predicting 3D protein structures in light of evolution S Bershtein, D Kleiner, D Mishmar Nature Ecology & Evolution 5 (9), 1195-1198, 2021 | 10 | 2021 |
| Metabolic response to point mutations reveals principles of modulation of in vivo enzyme activity and phenotype S Bhattacharyya, S Bershtein, BV Adkar, J Woodard, EI Shakhnovich Molecular systems biology 17 (6), e10200, 2021 | 10 | 2021 |
| Pan-cancer analysis of mitochondria chaperone-client co-expression reveals chaperone functional partitioning G Galai, H Ben-David, L Levin, MF Orth, TGP Grünewald, S Pilosof, ... Cancers 12 (4), 825, 2020 | 10 | 2020 |
| A High‐Throughput Continuous Spectroscopic Assay to Measure the Activity of Natural Product Methyltransferases H Simon‐Baram, S Roth, C Niedermayer, P Huber, M Speck, J Diener, ... ChemBioChem 23 (17), e202200162, 2022 | 9 | 2022 |
| SAMase of Bacteriophage T3 Inactivates Escherichia coli’s Methionine S-Adenosyltransferase by Forming Heteropolymers H Simon-Baram, D Kleiner, F Shmulevich, R Zarivach, R Zalk, H Tang, ... Mbio 12 (4), 10.1128/mbio. 01242-21, 2021 | 6 | 2021 |
| Chromosomal barcoding of E. coli populations reveals lineage diversity dynamics at high resolution J Lerner, M Manhart, W Jasinska, L Gauthier, AWR Serohijos, S Bershtein bioRxiv, 571505, 2019 | 4 | 2019 |
| Gene dosage experiments in enterobacteriaceae using arabinose-regulated promoters S Bhattacharyya, S Bershtein, EI Shakhnovich Bio-protocol 7 (14), e2396-e2396, 2017 | 4 | 2017 |
