Functional ion channels in pulmonary alveolar type I cells support a role for type I cells in lung ion transport MD Johnson, HF Bao, MN Helms, XJ Chen, Z Tigue, L Jain, LG Dobbs, ... Proceedings of the National Academy of Sciences 103 (13), 4964-4969, 2006 | 231 | 2006 |
The contribution of epithelial sodium channels to alveolar function in health and disease DC Eaton, MYN Helms, M Koval, HF Bao, L Jain Annual review of physiology 71, 403-423, 2009 | 230 | 2009 |
Dopamine regulation of amiloride-sensitive sodium channels in lung cells MN Helms, XJ Chen, S Ramosevac, DC Eaton, L Jain American Journal of Physiology-Lung Cellular and Molecular Physiology 290 (4 …, 2006 | 108 | 2006 |
Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/β-catenin signaling K Kolegraff, P Nava, MN Helms, CA Parkos, A Nusrat Molecular biology of the cell 22 (8), 1121-1134, 2011 | 106 | 2011 |
Extracellular matrix influences alveolar epithelial claudin expression and barrier function M Koval, C Ward, MK Findley, S Roser-Page, MN Helms, J Roman American journal of respiratory cell and molecular biology 42 (2), 172-180, 2010 | 93 | 2010 |
Redox regulation of epithelial sodium channels examined in alveolar type 1 and 2 cells patch-clamped in lung slice tissue MN Helms, L Jain, JL Self, DC Eaton Journal of Biological Chemistry 283 (33), 22875-22883, 2008 | 82 | 2008 |
Phosphatidylinositol 3, 4, 5-trisphosphate mediates aldosterone stimulation of epithelial sodium channel (ENaC) and interacts with γ-ENaC MN Helms, L Liu, YY Liang, O Al-Khalili, A Vandewalle, S Saxena, ... Journal of Biological Chemistry 280 (49), 40885-40891, 2005 | 82 | 2005 |
Regulation of sodium transport in mammalian collecting duct cells by aldosterone-induced kinase, SGK1: structure/function studies A Náray-Fejes-Tóth, MN Helms, JB Stokes, G Fejes-Tóth Molecular and cellular endocrinology 217 (1-2), 197-202, 2004 | 77 | 2004 |
Role of SGK1 in nitric oxide inhibition of ENaC in Na+-transporting epithelia MN Helms, L Yu, B Malik, DJ Kleinhenz, CM Hart, DC Eaton American Journal of Physiology-Cell Physiology 289 (3), C717-C726, 2005 | 75 | 2005 |
Aldosterone-induced increases in superoxide production counters nitric oxide inhibition of epithelial Na channel activity in A6 distal nephron cells L Yu, HF Bao, JL Self, DC Eaton, MN Helms American Journal of Physiology-Renal Physiology 293 (5), F1666-F1677, 2007 | 72 | 2007 |
Dopamine activates amiloride-sensitive sodium channels in alveolar type I cells in lung slice preparations MN Helms, J Self, HF Bao, LC Job, L Jain, DC Eaton American Journal of Physiology-Lung Cellular and Molecular Physiology 291 (4 …, 2006 | 71 | 2006 |
Hormone-regulated transepithelial Na+ transport in mammalian CCD cells requires SGK1 expression MN Helms, G Fejes-Tóth, A Náray-Fejes-Tóth American Journal of Physiology-Renal Physiology 284 (3), F480-F487, 2003 | 60 | 2003 |
Hyperoxia induces alveolar epithelial-to-mesenchymal cell transition S Vyas-Read, W Wang, S Kato, J Colvocoresses-Dodds, NH Fifadara, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 306 (4 …, 2014 | 55 | 2014 |
Rac1-mediated NADPH oxidase release of O2− regulates epithelial sodium channel activity in the alveolar epithelium Y Takemura, P Goodson, HF Bao, L Jain, MN Helms American Journal of Physiology-Lung Cellular and Molecular Physiology 298 (4 …, 2010 | 55 | 2010 |
H2O2 regulates lung epithelial sodium channel (ENaC) via ubiquitin-like protein Nedd8 CA Downs, A Kumar, LH Kreiner, NM Johnson, MN Helms Journal of Biological Chemistry 288 (12), 8136-8145, 2013 | 51 | 2013 |
Nadph oxidase regulates alveolar epithelial sodium channel activity and lung fluid balance in vivo via O2− signaling P Goodson, A Kumar, L Jain, K Kundu, N Murthy, M Koval, MN Helms American Journal of Physiology-Lung Cellular and Molecular Physiology 302 (4 …, 2012 | 51 | 2012 |
β-Adrenergic agonists differentially regulate highly selective and nonselective epithelial sodium channels to promote alveolar fluid clearance in vivo CA Downs, LH Kriener, L Yu, DC Eaton, L Jain, MN Helms American Journal of Physiology-Lung Cellular and Molecular Physiology 302 …, 2012 | 50 | 2012 |
Direct tracheal instillation of solutes into mouse lung MN Helms, E Torres-Gonzalez, P Goodson, M Rojas JoVE (Journal of Visualized Experiments), e1941, 2010 | 48 | 2010 |
Preclinical anatomical, molecular, and functional imaging of the lung with multiple modalities ST Gammon, N Foje, EM Brewer, E Owers, CA Downs, MD Budde, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 306 …, 2014 | 46 | 2014 |
Cellular and in vitro toxicity of nanodiamond-polyaniline composites in mammalian and bacterial cell P Villalba, MK Ram, H Gomez, V Bhethanabotla, MN Helms, A Kumar, ... Materials Science and Engineering: C 32 (3), 594-598, 2012 | 44 | 2012 |