Broad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona-and picornaviruses C Müller, FW Schulte, K Lange-Grünweller, W Obermann, R Madhugiri, ... Antiviral research 150, 123-129, 2018 | 230 | 2018 |
Inhibition of Cytosolic Phospholipase A2α Impairs an Early Step of Coronavirus Replication in Cell Culture C Müller, M Hardt, D Schwudke, BW Neuman, S Pleschka, J Ziebuhr Journal of virology 92 (4), 10.1128/jvi. 01463-17, 2018 | 136 | 2018 |
The natural compound silvestrol is a potent inhibitor of Ebola virus replication N Biedenkopf, K Lange-Grünweller, FW Schulte, A Weißer, C Müller, ... Antiviral research 137, 76-81, 2017 | 115 | 2017 |
Influenza virus-induced caspase-dependent enlargement of nuclear pores promotes nuclear export of viral ribonucleoprotein complexes D Mühlbauer, J Dzieciolowski, M Hardt, A Hocke, KL Schierhorn, ... Journal of virology 89 (11), 6009-6021, 2015 | 88 | 2015 |
Multi-level inhibition of coronavirus replication by chemical ER stress MS Shaban, C Müller, C Mayr-Buro, H Weiser, J Meier-Soelch, BV Albert, ... Nature communications 12 (1), 5536, 2021 | 81 | 2021 |
The MEK-inhibitor CI-1040 displays a broad anti-influenza virus activity in vitro and provides a prolonged treatment window compared to standard of care in vivo E Haasbach, C Müller, C Ehrhardt, A Schreiber, S Pleschka, S Ludwig, ... Antiviral research 142, 178-184, 2017 | 67 | 2017 |
Rational design of novel highly potent and selective phosphatidylinositol 4-kinase IIIβ (PI4KB) inhibitors as broad-spectrum antiviral agents and tools for chemical biology I Mejdrová, D Chalupská, P Plačková, C Müller, M Šála, M Klíma, ... Journal of medicinal chemistry 60 (1), 100-118, 2017 | 58 | 2017 |
Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (−) and the eIF4A-inhibitor Silvestrol C Müller, W Obermann, FW Schulte, K Lange-Grünweller, L Oestereich, ... Antiviral Research 175, 104706, 2020 | 55 | 2020 |
The secRNome of Listeria monocytogenes harbors small noncoding RNAs that are potent inducers of beta interferon R Frantz, L Teubner, T Schultze, L La Pietra, C Müller, K Gwozdzinski, ... MBio 10 (5), 10.1128/mbio. 01223-19, 2019 | 48 | 2019 |
Structure‐activity relationships of benzamides and isoindolines designed as SARS‐CoV protease inhibitors effective against SARS‐CoV‐2 A Welker, C Kersten, C Müller, R Madhugiri, C Zimmer, P Müller, ... ChemMedChem 16 (2), 340-354, 2021 | 45 | 2021 |
L-lysine acetylsalicylate+ glycine impairs coronavirus replication C Müller, N Karl, J Ziebuhr, S Pleschka J Antivir Antiretrovir 8 (4), 142-150, 2016 | 42 | 2016 |
The rocaglate CR-31-B (−) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo C Müller, W Obermann, N Karl, HG Wendel, G Taroncher-Oldenburg, ... Antiviral Research 186, 105012, 2021 | 36 | 2021 |
Inhibition of SARS-CoV-2 coronavirus proliferation by designer antisense-circRNAs C Pfafenrot, T Schneider, C Müller, LH Hung, S Schreiner, J Ziebuhr, ... Nucleic acids research 49 (21), 12502-12516, 2021 | 35 | 2021 |
Antiviral efficacy against influenza virus and pharmacokinetic analysis of a novel MEK-inhibitor, ATR-002, in cell culture and in the mouse model M Laure, H Hamza, J Koch-Heier, M Quernheim, C Müller, A Schreiber, ... Antiviral Research 178, 104806, 2020 | 35 | 2020 |
Ribonuclease from Bacillus Acts as an Antiviral Agent against Negative‐ and Positive‐Sense Single Stranded Human Respiratory RNA Viruses R Shah Mahmud, C Müller, Y Romanova, A Mostafa, V Ulyanova, ... BioMed Research International 2017 (1), 5279065, 2017 | 30 | 2017 |
Biomarkers in heart failure clinical trials. A review from the Biomarkers Working Group of the Heart Failure Association of the European Society of Cardiology A Bayes‐Genis, A Aimo, P Jhund, M Richards, RA de Boer, H Arfsten, ... European Journal of Heart Failure 24 (10), 1767-1777, 2022 | 29 | 2022 |
Antiviral activity of K22 against members of the order Nidovirales JCF Rappe, A de Wilde, H Di, C Müller, H Stalder, P V’kovski, E Snijder, ... Virus research 246, 28-34, 2018 | 27 | 2018 |
A novel antiviral strategy against MERS-CoV and HCoV-229E using binase to target viral genome replication C Müller, V Ulyanova, O Ilinskaya, S Pleschka, R Shah Mahmud Bionanoscience 7, 294-299, 2017 | 26 | 2017 |
Targeting the DEAD-box RNA helicase eIF4A with rocaglates—a pan-antiviral strategy for minimizing the impact of future RNA virus pandemics G Taroncher-Oldenburg, C Müller, W Obermann, J Ziebuhr, RK Hartmann, ... Microorganisms 9 (3), 540, 2021 | 25 | 2021 |
Bacterial ribonuclease binase exerts an intra-cellular anti-viral mode of action targeting viral RNAs in influenza a virus-infected MDCK-II cells R Shah Mahmud, A Mostafa, C Müller, P Kanrai, V Ulyanova, ... Virology journal 15, 1-12, 2018 | 24 | 2018 |