| SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters PJ Halfmann, S Iida, K Iwatsuki-Horimoto, T Maemura, M Kiso, ... Nature 603 (7902), 687-692, 2022 | 511 | 2022 |
| Generation of a broadly useful model for COVID-19 pathogenesis, vaccination, and treatment J Sun, Z Zhuang, J Zheng, K Li, RLY Wong, D Liu, J Huang, J He, A Zhu, ... Cell 182 (3), 734-743. e5, 2020 | 449 | 2020 |
| COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice J Zheng, LYR Wong, K Li, AK Verma, ME Ortiz, C Wohlford-Lenane, ... Nature 589 (7843), 603-607, 2021 | 445 | 2021 |
| Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy? LYR Wong, S Perlman Nature Reviews Immunology 22 (1), 47-56, 2022 | 155 | 2022 |
| Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3 PY Lui, LYR Wong, CL Fung, KL Siu, ML Yeung, KS Yuen, CP Chan, ... Emerging microbes & infections 5 (1), 1-9, 2016 | 137 | 2016 |
| The SARS-CoV-2 B. 1.1. 529 Omicron virus causes attenuated infection and disease in mice and hamsters M Diamond, P Halfmann, T Maemura, K Iwatsuki-Horimoto, S Iida, M Kiso, ... Research square, 2021 | 115 | 2021 |
| Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19 LYR Wong, J Zheng, K Wilhelmsen, K Li, ME Ortiz, NJ Schnicker, ... Nature 605 (7908), 146-151, 2022 | 95 | 2022 |
| Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection CS Dampalla, J Zheng, KD Perera, LYR Wong, DK Meyerholz, ... Proceedings of the National Academy of Sciences 118 (29), e2101555118, 2021 | 75 | 2021 |
| A molecular arms race between host innate antiviral response and emerging human coronaviruses LYR Wong, PY Lui, DY Jin Virologica Sinica 31, 12-23, 2016 | 62 | 2016 |
| PACT facilitates RNA-induced activation of MDA5 by promoting MDA5 oligomerization PY Lui, LYR Wong, TH Ho, SWN Au, CP Chan, KH Kok, DY Jin The Journal of Immunology 199 (5), 1846-1855, 2017 | 44 | 2017 |
| Middle East respiratory syndrome coronavirus ORF8b accessory protein suppresses type I IFN expression by impeding HSP70-dependent activation of IRF3 kinase IKKε LYR Wong, ZW Ye, PY Lui, X Zheng, S Yuan, L Zhu, SY Fung, KS Yuen, ... The Journal of Immunology 205 (6), 1564-1579, 2020 | 38 | 2020 |
| Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19 LYR Wong, J Zheng, K Wilhelmsen, K Li, ME Ortiz, NJ Schnicker, ... bioRxiv, 2021 | 25 | 2021 |
| Sensitization of non-permissive laboratory mice to SARS-CoV-2 with a replication-deficient adenovirus expressing human ACE2 LYR Wong, K Li, J Sun, Z Zhuang, J Zhao, PB McCray Jr, S Perlman STAR protocols 1 (3), 100169, 2020 | 19 | 2020 |
| K18-hACE2 mice for studies of COVID-19 treatments and pathogenesis including anosmia J Zheng, LY Roy Wong, K Li, AK Verma, M Ortiz, C Wohlford-Lenane, ... BioRxiv, 2020.08. 07.242073, 2020 | 15 | 2020 |
| Omicron subvariant BA. 5 efficiently infects lung cells M Hoffmann, LYR Wong, P Arora, L Zhang, C Rocha, A Odle, I Nehlmeier, ... Nature communications 14 (1), 3500, 2023 | 14 | 2023 |
| Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D J Zheng, D Meyerholz, LYR Wong, M Gelb, M Murakami, S Perlman The Journal of clinical investigation 131 (11), 2021 | 11 | 2021 |
| Identification of lysine acetylation sites on MERS-CoV replicase pp1ab L Zhu, SY Fung, G Xie, LYR Wong, DY Jin, Z Cai Molecular & Cellular Proteomics 19 (8), 1303-1309, 2020 | 11 | 2020 |
| Intranasal immunization with a vaccinia virus vaccine vector expressing pre-fusion stabilized SARS-CoV-2 spike fully protected mice against lethal challenge with the heavily … KV Kibler, M Szczerba, D Lake, AJ Roeder, M Rahman, BG Hogue, ... Vaccines 10 (8), 1172, 2022 | 10 | 2022 |
| Middle East respiratory syndrome coronavirus Spike protein variants exhibit geographic differences in virulence LYR Wong, J Zheng, A Sariol, S Lowery, DK Meyerholz, T Gallagher, ... Proceedings of the National Academy of Sciences 118 (24), e2102983118, 2021 | 9 | 2021 |
| SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice SA El-Kafrawy, A Odle, AT Abbas, AM Hassan, UA Abdel-Dayem, ... PLoS pathogens 18 (9), e1010782, 2022 | 8 | 2022 |
