| Discovery and structure–activity relationship of a bioactive fragment of ELABELA that modulates vascular and cardiac functions A Murza, X Sainsily, D Coquerel, J Côté, P Marx, É Besserer-Offroy, ... Journal of medicinal chemistry 59 (7), 2962-2972, 2016 | 135 | 2016 |
| Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties M Demeule, N Beaudet, A Régina, É Besserer-Offroy, A Murza, ... The Journal of clinical investigation 124 (3), 1199-1213, 2014 | 121 | 2014 |
| Elucidation of the structure–activity relationships of apelin: influence of unnatural amino acids on binding, signaling, and plasma stability A Murza, A Parent, E Besserer‐Offroy, H Tremblay, F Karadereye, ... ChemMedChem 7 (2), 318-325, 2012 | 112 | 2012 |
| Stability and degradation patterns of chemically modified analogs of apelin‐13 in plasma and cerebrospinal fluid A Murza, K Belleville, JM Longpré, P Sarret, É Marsault Peptide Science 102 (4), 297-303, 2014 | 76 | 2014 |
| The signaling signature of the neurotensin type 1 receptor with endogenous ligands É Besserer-Offroy, RL Brouillette, S Lavenus, U Froehlich, A Brumwell, ... European journal of pharmacology 805, 1-13, 2017 | 64 | 2017 |
| ELABELA improves cardio-renal outcome in fatal experimental septic shock D Coquerel, F Chagnon, X Sainsily, L Dumont, A Murza, J Côté, ... Critical care medicine 45 (11), e1139-e1148, 2017 | 61 | 2017 |
| C-Terminal modifications of apelin-13 significantly change ligand binding, receptor signaling, and hypotensive action A Murza, E Besserer-Offroy, J Cote, P Berube, JM Longpre, R Dumaine, ... Journal of medicinal chemistry 58 (5), 2431-2440, 2015 | 57 | 2015 |
| A systematic exploration of macrocyclization in apelin-13: impact on binding, signaling, stability, and cardiovascular effects K Tran, A Murza, X Sainsily, D Coquerel, J Cote, K Belleville, L Haroune, ... Journal of medicinal chemistry 61 (6), 2266-2277, 2018 | 35 | 2018 |
| Structure–activity relationship of novel macrocyclic biased apelin receptor agonists A Murza, X Sainsily, J Côté, L Bruneau-Cossette, É Besserer-Offroy, ... Organic & biomolecular chemistry 15 (2), 449-458, 2017 | 31 | 2017 |
| The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment É Besserer-Offroy, P Bérubé, J Côté, A Murza, JM Longpré, R Dumaine, ... Pharmacological research 131, 7-16, 2018 | 30 | 2018 |
| Inhibitors of type II transmembrane serine proteases in the treatment of diseases of the respiratory tract–A review of patent literature A Murza, SP Dion, PL Boudreault, A Désilets, R Leduc, É Marsault Expert Opinion on Therapeutic Patents 30 (11), 807-824, 2020 | 20 | 2020 |
| Constraining the side chain of C-terminal amino acids in apelin-13 greatly increases affinity, modulates signaling, and improves the pharmacokinetic profile K Tran, R Van Den Hauwe, X Sainsily, P Couvineau, J Cote, L Simard, ... Journal of Medicinal Chemistry 64 (9), 5345-5364, 2021 | 19 | 2021 |
| Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog P Tétreault, É Besserer-Offroy, RL Brouillette, A René, A Murza, R Fanelli, ... European Journal of Pharmacology 882, 173174, 2020 | 11 | 2020 |
| Size-Reduced Macrocyclic Analogues of [Pyr1]-apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects K Tran, X Sainsily, J Cote, D Coquerel, P Couvineau, S Saibi, L Haroune, ... Journal of medicinal chemistry 65 (1), 531-551, 2022 | 10 | 2022 |
| Structure–activity relationship and bioactivity of short analogues of ELABELA as agonists of the apelin receptor K Tran, A Murza, X Sainsily, E Delile, P Couvineau, J Cote, D Coquerel, ... Journal of Medicinal Chemistry 64 (1), 602-615, 2020 | 10 | 2020 |
| Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a … JB Thomas, M Vivancos, AM Giddings, RW Wiethe, KR Warner, A Murza, ... ACS Chemical Neuroscience 7 (9), 1225-1231, 2016 | 10 | 2016 |
| Gαi-biased apelin analog protects against isoproterenol-induced myocardial dysfunction in rats D Coquerel, E Delile, L Dumont, F Chagnon, A Murza, X Sainsily, ... American Journal of Physiology-Heart and Circulatory Physiology 320 (4 …, 2021 | 7 | 2021 |
| Simultaneous Ligand and Receptor Tracking through NMR Spectroscopy Enabled by Distinct 19F Labels JR Simmons, A Murza, MD Lumsden, C Kenward, É Marsault, JK Rainey International Journal of Molecular Sciences 20 (15), 3658, 2019 | 7 | 2019 |
| Apelins, ELABELA, and their derivatives: Peptidic regulators of the cardiovascular system and beyond A Murza, K Trân, L Bruneau‐Cossette, O Lesur, M Auger‐Messier, ... Peptide Science 111 (1), e24064, 2019 | 7 | 2019 |
| Data set describing the in vitro biological activity of JMV2009, a novel silylated neurotensin (8–13) analog É Besserer-Offroy, P Tétreault, RL Brouillette, A René, A Murza, R Fanelli, ... Data in Brief 31, 105884, 2020 | 4 | 2020 |
