| Variolins and related alkaloids SR Walker, EJ Carter, BC Huff, JC Morris Chemical reviews 109 (7), 3080-3098, 2009 | 290 | 2009 |
| Potent Inhibitors of a Shikimate Pathway Enzyme from Mycobacterium tuberculosis combining mechanism-And modeling-based design S Reichau, W Jiao, SR Walker, RD Hutton, EN Baker, EJ Parker Journal of Biological Chemistry 286 (18), 16197-16207, 2011 | 61 | 2011 |
| Characterization of the novel broad-spectrum kinase inhibitor CTx-0294885 as an affinity reagent for mass spectrometry-based kinome profiling L Zhang, IP Holmes, F Hochgräfe, SR Walker, NA Ali, ES Humphrey, ... Journal of proteome research 12 (7), 3104-3116, 2013 | 58 | 2013 |
| Structural determinants for small-molecule activation of skeletal muscle AMPK α2β2γ1 by the glucose importagog SC4 KRW Ngoei, CG Langendorf, NXY Ling, A Hoque, S Varghese, ... Cell chemical biology 25 (6), 728-737. e9, 2018 | 51 | 2018 |
| Concise syntheses of meridianins and meriolins using a catalytic domino amino-palladation reaction SR Walker, ML Czyz, JC Morris Organic letters 16 (3), 708-711, 2014 | 44 | 2014 |
| Synthesis and evaluation of a mechanism-based inhibitor of a 3-deoxy-D-arabino heptulosonate 7-phosphate synthase SR Walker, EJ Parker Bioorganic & medicinal chemistry letters 16 (11), 2951-2954, 2006 | 32 | 2006 |
| Substrate and reaction intermediate mimics as inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase SR Walker, H Cumming, EJ Parker Organic & Biomolecular Chemistry 7 (15), 3031-3035, 2009 | 25 | 2009 |
| Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer S Sharma, CY Chung, S Uryu, J Petrovic, J Cao, A Rickard, N Nady, ... Cell Chemical Biology, 2023 | 22 | 2023 |
| Synthesis and evaluation of dual site inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase SR Walker, W Jiao, EJ Parker Bioorganic & medicinal chemistry letters 21 (17), 5092-5097, 2011 | 21 | 2011 |
| Elimination of a hydroxyl group in FTY720 dramatically improves the phosphorylation rate E Jary, T Bee, SR Walker, SK Chung, KC Seo, JC Morris, AS Don Molecular pharmacology 78 (4), 685-692, 2010 | 20 | 2010 |
| 2-(hetero) aryl-benzimidazole and imidazopyridine derivatives as inhibitors of asparagime emethyl transferase PA Stupple, SR Walker, JA Pinson, HR Lagiakos, GE Lunniss, IP Holmes, ... US Patent 9,856,252, 2018 | 10 | 2018 |
| Tetrahydroisoquinoline derived PRMT5-inhibitors YE Bergman, RC Foitzik, BJ Morrow, MA Camerino, SR Walker, ... US Patent 10,494,376, 2019 | 9 | 2019 |
| Diagnostic fragmentations of adducts formed between carbanions and carbon disulfide in the gas phase. A joint experimental and theoretical study MJ Maclean, S Walker, T Wang, PCH Eichinger, PJ Sherman, JH Bowie Organic & biomolecular chemistry 8 (2), 371-377, 2010 | 8 | 2010 |
| Tetrahydroisoquinoline derived PRMT5-inhibitors RC Foitzik, MA Camerino, SR Walker, HR Lagiakos US Patent 10,647,708, 2020 | 7 | 2020 |
| Aminoindane-, aminotetrahydronaphthalene-and aminobenzocyclobutane-derived PRMT5-inhibitors YE Bergman, R Lessene, D Ganame, RC Foitzik, BJ Morrow, ... US Patent 10,005,792, 2018 | 7 | 2018 |
| FAK inhibitors IP Holmes, Y Bergman, GE Lunniss, M Nikac, N Choi, CF Hemley, ... US Patent 9,012,461, 2015 | 6 | 2015 |
| Tetrahydroisoquinolines as PRMT5 inhibitors YE Bergman, MA Camerino, SR Walker, PA Stupple US Patent 10,421,743, 2019 | 5 | 2019 |
| PRMT5 inhibitors as novel treatment for cancers H Falk, RC Foitzik, E Allan, M deSilva, H Yang, YE Bozikis, M Nikac, ... Cancer Research 75 (15_Supplement), 5371-5371, 2015 | 4 | 2015 |
| Inhibition of Focal Adhesion Kinase in Combination With Bevacizumab Reduces the Rate of Tumor Revascularization and Increases Survival in a Pre-clinical Model of Basal Breast … I Street, I Holmes, M Devlin, Y Bergman, J Doherty, A Natoli, H Falk, ... EUROPEAN JOURNAL OF CANCER 48, S203-S203, 2012 | 4 | 2012 |
| Selective FAK inhibitors IP Holmes, Y Bergman, GE Lunniss, M Nikac, N Choi, CF Hemley, ... US Patent 9,174,946, 2015 | 3 | 2015 |
