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Michael C. Young
Michael C. Young
Children's Hospital of Philadelphia
在 chop.edu 的电子邮件经过验证
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引用次数
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Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes
Y Sun, GF Papadaki, CA Devlin, JN Danon, MC Young, TJ Winters, ...
Science Advances 9 (8), eade7151, 2023
102023
Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes
Y Sun, MC Young, CH Woodward, JN Danon, HV Truong, S Gupta, ...
Proceedings of the National Academy of Sciences 120 (25), e2304055120, 2023
72023
Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules
GF Papadaki, O Ani, TJ Florio, MC Young, JN Danon, Y Sun, D Dersh, ...
Frontiers in Immunology 14, 1116906, 2023
32023
Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion
Y Sun, TJ Florio, S Gupta, MC Young, QF Marshall, SE Garfinkle, ...
Science immunology 8 (90), eadj5792, 2023
22023
Conformational plasticity of RAS Q61 family of neoepitopes results in distinct features for targeted recognition
AC McShan, D Flores-Solis, Y Sun, SE Garfinkle, JS Toor, MC Young, ...
Nature Communications 14 (1), 8204, 2023
12023
A Chicken Tapasin ortholog can chaperone empty HLA-B∗ 37: 01 molecules independent of other peptide-loading components
GF Papadaki, CH Woodward, MC Young, TJ Winters, GM Burslem, ...
Journal of Biological Chemistry 299 (10), 2023
12023
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