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Nadine D. Younan
Nadine D. Younan
Doctor of Biochemistry, Queen Mary University of London
在 qmul.ac.uk 的电子邮件经过验证
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引用次数
引用次数
年份
A comparison of three fluorophores for the detection of amyloid fibers and prefibrillar oligomeric assemblies. ThT (thioflavin T); ANS (1-anilinonaphthalene-8-sulfonic acid …
ND Younan, JH Viles
Biochemistry 54 (28), 4297-4306, 2015
1872015
The cellular prion protein traps Alzheimer's Aβ in an oligomeric form and disassembles amyloid fibers
ND Younan, CJ Sarell, P Davies, DR Brown, JH Viles
The FASEB Journal 27 (5), 1847, 2013
1012013
Copper (II)-induced secondary structure changes and reduced folding stability of the prion protein
ND Younan, M Klewpatinond, P Davies, AV Ruban, DR Brown, JH Viles
Journal of molecular biology 410 (3), 369-382, 2011
712011
Cu2+ accentuates distinct misfolding of Aβ(1–40) and Aβ(1–42) peptides, and potentiates membrane disruption
CJ Matheou, ND Younan, JH Viles
Biochemical Journal 466 (2), 233-242, 2015
662015
Methionine oxidation perturbs the structural core of the prion protein and suggests a generic misfolding pathway
ND Younan, RC Nadal, P Davies, DR Brown, JH Viles
Journal of Biological Chemistry 287 (34), 28263-28275, 2012
572012
Prion protein stabilizes amyloid-β (Aβ) oligomers and enhances Aβ neurotoxicity in a Drosophila model of Alzheimer's disease
ND Younan, KF Chen, RS Rose, DC Crowther, JH Viles
Journal of Biological Chemistry 293 (34), 13090-13099, 2018
442018
N‐Terminally Truncated Amyloid‐β(1140/42) Cofibrillizes with its Full‐Length Counterpart: Implications for Alzheimer's Disease
JD Barritt, ND Younan, JH Viles
Angewandte Chemie 129 (33), 9948-9951, 2017
342017
The rapid exchange of Zinc2+ enables trace levels to profoundly influence amyloid-β misfolding and dominates assembly outcomes in Cu2+/Zn2+ mixtures
CJ Matheou, ND Younan, JH Viles
Journal of Molecular Biology 428 (14), 2832-2846, 2016
252016
Structural analysis of the starfish SALMFamide neuropeptides S1 and S2: The N-terminal region of S2 facilitates self-association
CB Otara, CE Jones, ND Younan, JH Viles, MR Elphick
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (2), 358-365, 2014
62014
Bioactivity and structural properties of chimeric analogs of the starfish SALMFamide neuropeptides S1 and S2
CE Jones, CB Otara, ND Younan, JH Viles, MR Elphick
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (10), 1842-1850, 2014
52014
The cellular prion protein traps Alzheimer’s Aß in an oligomeric form and disassembles amyloid fibers
ND Younan, CJ Sarell, P Davies, DR Brown, JH Viles
1
The influence of copper (II) ions on the structure and stability of the prion protein and its interaction with the amyloid-beta peptides.
ND Younan
Queen Mary University of London, 2012
2012
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