Cellular senescence and senolytics: the path to the clinic S Chaib, T Tchkonia, JL Kirkland Nature medicine 28 (8), 1556-1568, 2022 | 586 | 2022 |
Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response VE Zannella, A Dal Pra, H Muaddi, TD McKee, S Stapleton, J Sykes, ... Clinical cancer research 19 (24), 6741-6750, 2013 | 330 | 2013 |
A versatile drug delivery system targeting senescent cells D Muñoz‐Espín, M Rovira, I Galiana, C Giménez, B Lozano‐Torres, ... EMBO molecular medicine 10 (9), e9355, 2018 | 271 | 2018 |
An OFF–ON Two-Photon Fluorescent Probe for Tracking Cell Senescence in Vivo B Lozano-Torres, I Galiana, M Rovira, E Garrido, S Chaib, A Bernardos, ... Journal of the American Chemical Society 139 (26), 8808-8811, 2017 | 164 | 2017 |
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype M Maus, V López-Polo, L Mateo, M Lafarga, M Aguilera, E De Lama, ... Nature Metabolism 5 (12), 2111-2130, 2023 | 52 | 2023 |
MATE2 expression is associated with cancer cell response to metformin S Chowdhury, E Yung, M Pintilie, H Muaddi, S Chaib, MT Yeung, ... PLoS One 11 (12), e0165214, 2016 | 35 | 2016 |
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2 S Chaib, JA López-Domínguez, M Lalinde-Gutiérrez, N Prats, I Marin, ... Nature cancer 5 (3), 448-462, 2024 | 30 | 2024 |
Obesity, senescence, and senolytics S Chaib, T Tchkonia, JL Kirkland From obesity to diabetes, 165-180, 2021 | 18 | 2021 |
Transporter-mediated interaction between platinum drugs and sorafenib at the cellular level V Schneider, S Chaib, C Spanier, M Knapp, V Moscvin, L Scordovillo, ... The AAPS Journal 20, 1-12, 2018 | 6 | 2018 |
The efficacy of chemotherapy is limited by intratumoural senescent cells that persist through the upregulation of PD-L2 S Chaib, JA López-Domínguez, M Lalinde, N Prats, I Marin, K Meyer, ... bioRxiv, 2022.11. 04.501681, 2022 | 5 | 2022 |
Development of a novel senolytic by precise disruption of FOXO4-p53 complex U Tripathi, S Chaib, EOW Gerdes, KA Hogan, Y Zhu EBioMedicine 74, 2021 | 4 | 2021 |
Profiling microRNA expression during senescence and aging: mining for a diagnostic tool of senescent-cell burden M Weigl, TL Krammer, M Pultar, M Wieser, S Chaib, M Suda, A Diendorfer, ... bioRxiv, 2024.04. 10.588794, 2024 | 2 | 2024 |
Role for Merlin/NF2 in transcription elongation through interaction with the PAF complex AE Roehrig, K Klupsch, JA Oses-Prieto, S Chaib, S Henderson, W Emmett, ... BioRxiv, 717769, 2019 | 2 | 2019 |
Cell-cell adhesion regulates Merlin/NF2 interaction with the PAF complex AE Roehrig, K Klupsch, JA Oses-Prieto, S Chaib, S Henderson, W Emmett, ... Plos one 16 (8), e0254697, 2021 | 1 | 2021 |
PD-L2 expression in senescent cancer cells limits tumor clearance after chemotherapy JA Lopez-Dominguez, S Chaib, M Serrano NATURE CANCER 5 (3), 382-383, 2024 | | 2024 |
PD-L2 mediates immune evasion of chemotherapy-treated tumours and protects from tissue injury S Chaib | | 2020 |
Pd-l2 media la evasión inmune de tumores tratados con quimioterapia y protege contra lesiones tisulares S Chaib Universidad Autónoma de Madrid, 2020 | | 2020 |
Senescent cell transplantation into the skin induces age‐related peripheral dysfunction and cognitive decline AC Franco, H Martini, S Victorelli, AB Lagnado, SP Wyles, JL Rowsey, ... Aging Cell, e14340, 0 | | |
Research briefing JA Lopez-Dominguez, S Chaib, M Serrano | | |