| Apoptosis-inducing factor triggered by poly (ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia C Culmsee, C Zhu, S Landshamer, B Becattini, E Wagner, M Pellecchia, ... Journal of Neuroscience 25 (44), 10262-10272, 2005 | 445 | 2005 |
| JNK at the crossroad of obesity, insulin resistance, and cell stress response G Solinas, B Becattini Molecular metabolism 6 (2), 174-184, 2017 | 414 | 2017 |
| Identification of a new JNK inhibitor targeting the JNK-JIP interaction site JL Stebbins, SK De, T Machleidt, B Becattini, J Vazquez, C Kuntzen, ... Proceedings of the National Academy of Sciences 105 (43), 16809-16813, 2008 | 225 | 2008 |
| Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-XL B Becattini, S Kitada, M Leone, E Monosov, S Chandler, D Zhai, TJ Kipps, ... Chemistry & biology 11 (3), 389-395, 2004 | 207 | 2004 |
| Bid-induced release of AIF from mitochondria causes immediate neuronal cell death S Landshamer, M Hoehn, N Barth, S Duvezin-Caubet, G Schwake, ... Cell Death & Differentiation 15 (10), 1553-1563, 2008 | 186 | 2008 |
| Efficient synthetic inhibitors of anthrax lethal factor M Forino, S Johnson, TY Wong, DV Rozanov, AY Savinov, W Li, ... Proceedings of the National Academy of Sciences 102 (27), 9499-9504, 2005 | 166 | 2005 |
| Targeting apoptosis via chemical design: inhibition of bid-induced cell death by small organic molecules B Becattini, S Sareth, D Zhai, KJ Crowell, M Leone, JC Reed, ... Chemistry & biology 11 (8), 1107-1117, 2004 | 130 | 2004 |
| Structure–activity relationships by interligand NOE-based design and synthesis of antiapoptotic compounds targeting Bid B Becattini, C Culmsee, M Leone, D Zhai, X Zhang, KJ Crowell, MF Rega, ... Proceedings of the National Academy of Sciences 103 (33), 12602-12606, 2006 | 125 | 2006 |
| SAR by ILOEs: An NMR‐based approach to reverse chemical genetics B Becattini, M Pellecchia Chemistry–A European Journal 12 (10), 2658-2662, 2006 | 100 | 2006 |
| NMR-based techniques in the hit identification and optimisation processes M Pellecchia, B Becattini, KJ Crowell, R Fattorusso, M Forino, M Fragai, ... Expert opinion on therapeutic targets 8 (6), 597-611, 2004 | 100 | 2004 |
| Boron: A key element in radical reactions P Renaud, A Beauseigneur, A Brecht-Forster, B Becattini, V Darmency, ... Pure and applied chemistry 79 (2), 223-233, 2007 | 98 | 2007 |
| Hyperinsulinemia and insulin resistance in the obese may develop as part of a homeostatic response to elevated free fatty acids: A mechanistic case-control and a population … E Fryk, J Olausson, K Mossberg, L Strindberg, M Schmelz, H Brogren, ... EBioMedicine 65, 2021 | 89 | 2021 |
| Insulin-driven PI3K-AKT signaling in the hepatocyte is mediated by redundant PI3Kα and PI3Kβ activities and is promoted by RAS A Molinaro, B Becattini, A Mazzoli, A Bleve, L Radici, I Maxvall, ... Cell metabolism 29 (6), 1400-1409. e5, 2019 | 89 | 2019 |
| PER2 promotes glucose storage to liver glycogen during feeding and acute fasting by inducing Gys2 PTG and GL expression F Zani, L Breasson, B Becattini, A Vukolic, JP Montani, U Albrecht, ... Molecular metabolism 2 (3), 292-305, 2013 | 89 | 2013 |
| PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance B Becattini, R Marone, F Zani, D Arsenijevic, J Seydoux, JP Montani, ... Proceedings of the National Academy of Sciences 108 (42), E854-E863, 2011 | 66 | 2011 |
| Yersinia phosphatase induces mitochondrially dependent apoptosis of T cells S Bruckner, S Rhamouni, L Tautz, JB Denault, A Alonso, B Becattini, ... Journal of Biological Chemistry 280 (11), 10388-10394, 2005 | 57 | 2005 |
| Thiophenol‐Mediated 1, 5‐Hydrogen Atom Abstraction: Easy Access to Mono‐and Bicyclic Compounds F Beaufils, F Dénès, B Becattini, P Renaud, K Schenk Advanced Synthesis & Catalysis 347 (11‐13), 1587-1594, 2005 | 38 | 2005 |
| Insulin signaling and glucose metabolism in different hepatoma cell lines deviate from hepatocyte physiology toward a convergent aberrant phenotype A Molinaro, B Becattini, G Solinas Scientific reports 10 (1), 12031, 2020 | 33 | 2020 |
| PI3Kγ activity in leukocytes promotes adipose tissue inflammation and early-onset insulin resistance during obesity L Breasson, B Becattini, C Sardi, A Molinaro, F Zani, R Marone, ... Science signaling 10 (488), eaaf2969, 2017 | 31 | 2017 |
| PSD3 downregulation confers protection against fatty liver disease RM Mancina, K Sasidharan, A Lindblom, Y Wei, E Ciociola, ... Nature metabolism 4 (1), 60-75, 2022 | 25 | 2022 |
