| Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 864 | 2015 |
| SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis K Tahlan, R Wilson, DB Kastrinsky, K Arora, V Nair, E Fischer, SW Barnes, ... Antimicrobial agents and chemotherapy 56 (4), 1797-1809, 2012 | 573 | 2012 |
| Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis KM Backus, HI Boshoff, CS Barry, O Boutureira, MK Patel, F D'hooge, ... Nature chemical biology 7 (4), 228-235, 2011 | 242 | 2011 |
| Biosynthesis and recycling of nicotinamide cofactors in Mycobacterium tuberculosis: an essential role for NAD in nonreplicating bacilli HIM Boshoff, X Xu, K Tahlan, CS Dowd, K Pethe, LR Camacho, TH Park, ... Journal of Biological Chemistry 283 (28), 19329-19341, 2008 | 195 | 2008 |
| Initiation of actinorhodin export in Streptomyces coelicolor K Tahlan, SK Ahn, A Sing, TD Bodnaruk, AR Willems, AR Davidson, ... Molecular microbiology 63 (4), 951-961, 2007 | 162 | 2007 |
| A community resource for paired genomic and metabolomic data mining MA Schorn, S Verhoeven, L Ridder, F Huber, DD Acharya, AA Aksenov, ... Nature Chemical Biology 17 (4), 363-368, 2021 | 102 | 2021 |
| Expression of ccaR, Encoding the Positive Activator of Cephamycin C and Clavulanic Acid Production in Streptomyces clavuligerus, Is Dependent on bldG DRD Bignell, K Tahlan, KR Colvin, SE Jensen, BK Leskiw Antimicrobial agents and chemotherapy 49 (4), 1529-1541, 2005 | 86 | 2005 |
| Origins of the β-lactam rings in natural products K Tahlan, SE Jensen The Journal of antibiotics 66 (7), 401-410, 2013 | 75 | 2013 |
| Klebsiella species associated with bovine mastitis in Newfoundland MP Podder, L Rogers, PK Daley, GP Keefe, HG Whitney, K Tahlan PloS one 9 (9), e106518, 2014 | 74 | 2014 |
| Crystal structures of the Streptomyces coelicolor TetR-like protein ActR alone and in complex with actinorhodin or the actinorhodin biosynthetic precursor (S)-DNPA AR Willems, K Tahlan, T Taguchi, K Zhang, ZZ Lee, K Ichinose, MS Junop, ... Journal of molecular biology 376 (5), 1377-1387, 2008 | 72 | 2008 |
| Two sets of paralogous genes encode the enzymes involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerus K Tahlan, HU Park, A Wong, PH Beatty, SE Jensen Antimicrobial agents and chemotherapy 48 (3), 930-939, 2004 | 69 | 2004 |
| A two-step mechanism for the activation of actinorhodin export and resistance in Streptomyces coelicolor Y Xu, A Willems, C Au-Yeung, K Tahlan, JR Nodwell MBio 3 (5), 10.1128/mbio. 00191-12, 2012 | 61 | 2012 |
| Ligand recognition by ActR, a TetR-like regulator of actinorhodin export K Tahlan, Z Yu, Y Xu, AR Davidson, JR Nodwell Journal of molecular biology 383 (4), 753-761, 2008 | 55 | 2008 |
| 5S clavam biosynthetic genes are located in both the clavam and paralog gene clusters in Streptomyces clavuligerus K Tahlan, C Anders, A Wong, RH Mosher, PH Beatty, MJ Brumlik, A Griffin, ... Chemistry & biology 14 (2), 131-142, 2007 | 49 | 2007 |
| The Paralogous Pairs of Genes Involved in Clavulanic Acid and Clavam Metabolite Biosynthesis Are Differently Regulated in Streptomyces clavuligerus K Tahlan, C Anders, SE Jensen Journal of bacteriology 186 (18), 6286-6297, 2004 | 47 | 2004 |
| Three unlinked gene clusters are involved in clavam metabolite biosynthesis in Streptomyces clavuligerus K Tahlan, HU Park, SE Jensen Canadian journal of microbiology 50 (10), 803-810, 2004 | 44 | 2004 |
| Genome-Wide Diversity and Phylogeography of Mycobacterium avium subsp. paratuberculosis in Canadian Dairy Cattle C Ahlstrom, HW Barkema, K Stevenson, RN Zadoks, R Biek, R Kao, ... Plos one 11 (2), e0149017, 2016 | 32 | 2016 |
| Investigation of Transcription Repression and Small-Molecule Responsiveness by TetR-Like Transcription Factors Using a Heterologous Escherichia coli-Based … SK Ahn, K Tahlan, Z Yu, J Nodwell Journal of bacteriology 189 (18), 6655-6664, 2007 | 30 | 2007 |
| Comparative Genomics and Metabolomics Analyses of Clavulanic Acid-Producing Streptomyces Species Provides Insight Into Specialized Metabolism NF AbuSara, BM Piercey, MA Moore, AA Shaikh, LF Nothias, ... Frontiers in Microbiology 10, 2550, 2019 | 29 | 2019 |
| Transcriptional and translational analysis of the ccaR gene from Streptomyces clavuligerus L Wang, K Tahlan, TL Kaziuk, DC Alexander, SE Jensen Microbiology 150 (12), 4137-4145, 2004 | 27 | 2004 |
