Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice CA Lasagna-Reeves, DL Castillo-Carranza, U Sengupta, AL Clos, ... Molecular neurodegeneration 6, 1-14, 2011 | 661 | 2011 |
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease CA Lasagna-Reeves, DL Castillo-Carranza, U Sengupta, J Sarmiento, ... The FASEB Journal 26 (5), 1946, 2012 | 602 | 2012 |
Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau CA Lasagna-Reeves, DL Castillo-Carranza, U Sengupta, ... Scientific reports 2 (1), 700, 2012 | 584 | 2012 |
Preparation and characterization of neurotoxic tau oligomers CA Lasagna-Reeves, DL Castillo-Carranza, MJ Guerrero-Muñoz, ... Biochemistry 49 (47), 10039-10041, 2010 | 391 | 2010 |
Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles DL Castillo-Carranza, U Sengupta, MJ Guerrero-Muñoz, ... Journal of Neuroscience 34 (12), 4260-4272, 2014 | 319 | 2014 |
Tau oligomers: cytotoxicity, propagation, and mitochondrial damage SS Shafiei, MJ Guerrero-Muñoz, DL Castillo-Carranza Frontiers in aging neuroscience 9, 83, 2017 | 299 | 2017 |
Specific targeting of tau oligomers in htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds DL Castillo-Carranza, JE Gerson, U Sengupta, MJ Guerrero-Muñoz, ... Journal of Alzheimer's Disease 40 (s1), S97-S111, 2014 | 201 | 2014 |
Tau oligomers: the toxic player at synapses in Alzheimer’s disease MJ Guerrero-Muñoz, J Gerson, DL Castillo-Carranza Frontiers in cellular neuroscience 9, 464, 2015 | 192 | 2015 |
Pathological interface between oligomeric alpha-synuclein and tau in synucleinopathies U Sengupta, MJ Guerrero-Muñoz, DL Castillo-Carranza, ... Biological psychiatry 78 (10), 672-683, 2015 | 191 | 2015 |
Tau oligomers associate with inflammation in the brain and retina of tauopathy mice and in neurodegenerative diseases AN Nilson, KC English, JE Gerson, T Barton Whittle, C Nicolas Crain, ... Journal of Alzheimer's Disease 55 (3), 1083-1099, 2017 | 176 | 2017 |
Rapid accumulation of endogenous tau oligomers in a rat model of traumatic brain injury: possible link between traumatic brain injury and sporadic tauopathies BE Hawkins, S Krishnamurthy, DL Castillo-Carranza, U Sengupta, ... Journal of Biological Chemistry 288 (23), 17042-17050, 2013 | 175 | 2013 |
Tau immunotherapy modulates both pathological tau and upstream amyloid pathology in an Alzheimer's disease mouse model DL Castillo-Carranza, MJ Guerrero-Muñoz, U Sengupta, C Hernandez, ... Journal of Neuroscience 35 (12), 4857-4868, 2015 | 160 | 2015 |
Therapeutic approaches against common structural features of toxic oligomers shared by multiple amyloidogenic proteins MJ Guerrero-Muñoz, DL Castillo-Carranza, R Kayed Biochemical pharmacology 88 (4), 468-478, 2014 | 119 | 2014 |
Cerebral microvascular accumulation of tau oligomers in Alzheimer’s disease and related tauopathies DL Castillo-Carranza, AN Nilson, CE Van Skike, JB Jahrling, K Patel, ... Aging and disease 8 (3), 257, 2017 | 112 | 2017 |
Tau oligomers derived from traumatic brain injury cause cognitive impairment and accelerate onset of pathology in Htau mice J Gerson, DL Castillo-Carranza, U Sengupta, R Bodani, DS Prough, ... Journal of neurotrauma 33 (22), 2034-2043, 2016 | 111 | 2016 |
Dual role of p53 amyloid formation in cancer; loss of function and gain of toxicity CA Lasagna-Reeves, AL Clos, D Castillo-Carranza, U Sengupta, ... Biochemical and biophysical research communications 430 (3), 963-968, 2013 | 103 | 2013 |
Tau oligomers in cerebrospinal fluid in Alzheimer's disease U Sengupta, E Portelius, O Hansson, K Farmer, D Castillo‐Carranza, ... Annals of clinical and translational neurology 4 (4), 226-235, 2017 | 96 | 2017 |
α-Synuclein oligomers induce a unique toxic tau strain DL Castillo-Carranza, MJ Guerrero-Muñoz, U Sengupta, JE Gerson, ... Biological psychiatry 84 (7), 499-508, 2018 | 90 | 2018 |
Advances in therapeutics for neurodegenerative tauopathies: moving toward the specific targeting of the most toxic tau species JE Gerson, DL Castillo-Carranza, R Kayed ACS chemical neuroscience 5 (9), 752-769, 2014 | 90 | 2014 |
The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes CA Lasagna-Reeves, U Sengupta, D Castillo-Carranza, JE Gerson, ... Acta neuropathologica communications 2, 1-13, 2014 | 87 | 2014 |