Caspase-11 mediates neutrophil chemotaxis and extracellular trap formation during acute gouty arthritis through alteration of cofilin phosphorylation K Caution, N Young, F Robledo-Avila, K Krause, A Abu Khweek, ... Frontiers in Immunology 10, 2519, 2019 | 62 | 2019 |
CASP4/caspase-11 promotes autophagosome formation in response to bacterial infection K Krause, K Caution, A Badr, K Hamilton, A Saleh, K Patel, S Seveau, ... Autophagy 14 (11), 1928-1942, 2018 | 57 | 2018 |
Elevated expression of MiR-17 in microglia of Alzheimer’s disease patients abrogates autophagy-mediated amyloid-β degradation S Estfanous, KP Daily, M Eltobgy, NP Deems, MNK Anne, K Krause, ... Frontiers in immunology 12, 705581, 2021 | 44 | 2021 |
Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis MM Eltobgy, A Zani, AD Kenney, S Estfanous, E Kim, A Badr, C Carafice, ... Proceedings of the National Academy of Sciences 119 (21), e2202012119, 2022 | 35 | 2022 |
Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo S Estfanous, K Krause, MNK Anne, M Eltobgy, K Caution, A Abu Khweek, ... Scientific reports 11 (1), 855, 2021 | 32 | 2021 |
The expression of Mirc1/Mir17–92 cluster in sputum samples correlates with pulmonary exacerbations in cystic fibrosis patients K Krause, BT Kopp, MF Tazi, K Caution, K Hamilton, A Badr, C Shrestha, ... Journal of Cystic Fibrosis 17 (4), 454-461, 2018 | 31 | 2018 |
Caspase‐11 counteracts mitochondrial ROS‐mediated clearance of Staphylococcus aureus in macrophages K Krause, K Daily, S Estfanous, K Hamilton, A Badr, A Abu Khweek, ... EMBO reports 20 (12), e48109, 2019 | 30 | 2019 |
Methylomic correlates of autophagy activity in cystic fibrosis K Caution, A Pan, K Krause, A Badr, K Hamilton, A Vaidya, H Gosu, ... Journal of Cystic Fibrosis 18 (4), 491-500, 2019 | 25 | 2019 |
CFTR modulators restore acidification of autophago-lysosomes and bacterial clearance in cystic fibrosis macrophages A Badr, M Eltobgy, K Krause, K Hamilton, S Estfanous, KP Daily, ... Frontiers in Cellular and Infection Microbiology 12, 819554, 2022 | 13 | 2022 |
Defective immunometabolism pathways in cystic fibrosis macrophages K Hamilton, K Krause, A Badr, K Daily, S Estfanous, M Eltobgy, ... Journal of Cystic Fibrosis 20 (4), 664-672, 2021 | 7 | 2021 |
Caspase-11 regulates lung inflammation in response to house dust mites AA Khweek, MR Joldrichsen, E Kim, Z Attia, K Krause, K Daily, ... Cellular immunology 370, 104425, 2021 | 5 | 2021 |
Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and thrombosis M Eltobgy, A Zani, AD Kenney, S Estfanous, E Kim, A Badr, C Carafice, ... bioRxiv, 2021.09. 24.461743, 2021 | 4 | 2021 |
Author Correction: Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo S Estfanous, K Krause, MNK Anne, M Eltobgy, K Caution, AA Khweek, ... Scientific Reports 11 (1), 12447, 2021 | 2 | 2021 |
Elevated Expression of MiR-17 in Microglia of Alzheimer’s Disease Patients Abrogates Autophagy-Mediated Amyloid-b Degradation S Estfanous, KP Daily, M Eltobgy, NP Deems, MNK Anne, K Krause, ... Front. Immunol. 12: 705581. doi: 10.3389/fimmu, 2021 | 1 | 2021 |
Microglia-targeted inhibition of miR-17 via mannose-coated lipid nanoparticles improves pathology and behavior in a mouse model of Alzheimer’s disease A Badr, KP Daily, M Eltobgy, S Estfanous, MH Tan, JCT Kuo, O Whitham, ... Brain, Behavior, and Immunity 119, 919-944, 2024 | | 2024 |
DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s disease KP Daily, A Badr, M Eltobgy, S Estfanous, O Whitham, MH Tan, C Carafice, ... Alzheimer's Research & Therapy 16 (1), 29, 2024 | | 2024 |
496 Cystic fibrosis transmembrane conductance regulator modulators restore autophagic-dependent bacterial clearance by increasing acidification of autophagolysosomes of F508del … A Badr, M Eltobgy, K Krause, E Cormet-Boyaka, A Amer Journal of Cystic Fibrosis 21, S280-S281, 2022 | | 2022 |
Crosstalk Between Autophagy and Nutrigenomics in Neurodegenerative Diseases AE Russell, A Badr, A Rai, C Carafice, A Rai, KP Daily, O Whitham, ... Nutrigenomics and the Brain, 175-199, 2022 | | 2022 |
Identification of the role of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in the autophagy and lysosomal dysfunction in CF macrophages AA Badr The Ohio State University, 2021 | | 2021 |
CFTR MODULATORS-MEDIATED CORRECTION OF LYSOSOMAL DYSFUNCTION RESTORES AUTOPHAGY AND BACTERIAL CLEARANCE IN CF MACROPHAGES AA Badr, K Krause, M Eltobgy, K Hamilton, S Estfanous, A Abu Khweek, ... PEDIATRIC PULMONOLOGY 55, S140-S140, 2020 | | 2020 |