Characterization of the Inflammatory Response to Severe COVID-19 Illness OJ McElvaney, N McEvoy, OF McElvaney, TP Carroll, MP Murphy, ... American Journal of Respiratory and Critical Care Medicine, 2020 | 672 | 2020 |
α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8 DA Bergin, EP Reeves, P Meleady, M Henry, OJ McElvaney, TP Carroll, ... The Journal of clinical investigation 120 (12), 4236-4250, 2010 | 331 | 2010 |
Neutrophil elastase up‐regulates interleukin‐8 via toll‐like receptor 4 JM Devaney, CM Greene, CC Taggart, TP Carroll, SJ O'Neill, ... FEBS letters 544 (1-3), 129-132, 2003 | 292 | 2003 |
TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells CM Greene, TP Carroll, SGJ Smith, CC Taggart, J Devaney, S Griffin, ... The Journal of Immunology 174 (3), 1638-1646, 2005 | 290 | 2005 |
Alpha-1 antitrypsin deficiency C Greene, S Miller, T Carroll, C McLean, M O'Mahony, M Lawless, ... Journal of Inherited Metabolic Disease 31 (1), 21-34, 2008 | 280* | 2008 |
Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/IRAK/TRAF-6 in human bronchial epithelium DE Walsh, CM Greene, TP Carroll, CC Taggart, PM Gallagher, SJ O'Neill, ... Journal of Biological Chemistry 276 (38), 35494-35499, 2001 | 209 | 2001 |
Clarification of the risk of chronic obstructive pulmonary disease in α1-antitrypsin deficiency PiMZ heterozygotes K Molloy, CP Hersh, VB Morris, TP Carroll, CA O’Connor, JA Lasky-Su, ... American journal of respiratory and critical care medicine 189 (4), 419-427, 2014 | 185 | 2014 |
Evidence for unfolded protein response activation in monocytes from individuals with α-1 antitrypsin deficiency TP Carroll, CM Greene, CA O’Connor, ÁM Nolan, SJ O’Neill, ... The Journal of Immunology 184 (8), 4538-4546, 2010 | 140 | 2010 |
Elastolytic proteases: inflammation resolution and dysregulation in chronic infective lung disease CC Taggart, CM Greene, TP Carroll, SJ O'Neill, NG McElvaney American journal of respiratory and critical care medicine 171 (10), 1070-1076, 2005 | 139 | 2005 |
Alpha-1 antitrypsin deficiency E Kelly, CM Greene, TP Carroll, NG McElvaney, SJ O’Neill Respiratory Medicine CME 4 (1), 1-8, 2011 | 133 | 2011 |
Alpha-1 antitrypsin deficiency E Kelly, CM Greene, TP Carroll, NG McElvaney, SJ O'Neill Respiratory medicine 104 (6), 763-772, 2010 | 133 | 2010 |
The prevalence of alpha-1 antitrypsin deficiency in Ireland TP Carroll, CA O'Connor, O Floyd, J McPartlin, DP Kelleher, G O'Brien, ... Respiratory research 12 (1), 91, 2011 | 104 | 2011 |
Alpha-1 antitrypsin deficiency: a conformational disease associated with lung and liver manifestations CM Greene, SD Miller, T Carroll, C McLean, M O'Mahony, MW Lawless, ... Journal of Inherited Metabolic Disease 31 (Issue 1), 21-34, 2008 | 95 | 2008 |
miR-199a-5p silencing regulates the unfolded protein response in chronic obstructive pulmonary disease and α1-antitrypsin deficiency T Hassan, TP Carroll, PG Buckley, R Cummins, SJ O’Neill, NG McElvaney, ... American journal of respiratory and critical care medicine 189 (3), 263-273, 2014 | 88 | 2014 |
Selenoprotein S/Seps1 modifies endoplasmic reticulum stress in z variant α1-antitrypsin deficiency E Kelly, CM Greene, TP Carroll, NG McElvaney, SJ O'Neill Journal of Biological Chemistry 284 (25), 16891-16897, 2009 | 82 | 2009 |
Identification and characterisation of eight novel SERPINA1 Null mutations I Ferrarotti, TP Carroll, S Ottaviani, AM Fra, G O’Brien, K Molloy, L Corda, ... Orphanet journal of rare diseases 9 (1), 172, 2014 | 69 | 2014 |
The impact of smoke exposure on the clinical phenotype of alpha-1 antitrypsin deficiency in Ireland: exploiting a national registry to understand a rare disease ME O’Brien, K Pennycooke, TP Carroll, J Shum, LT Fee, C O’Connor, ... COPD: Journal of Chronic Obstructive Pulmonary Disease 12 (sup1), 2-9, 2015 | 46 | 2015 |
Viral inhibition of IL-1-and neutrophil elastase-induced inflammatory responses in bronchial epithelial cells TP Carroll, CM Greene, CC Taggart, AG Bowie, SJ O’Neill, NG McElvaney The Journal of Immunology 175 (11), 7594-7601, 2005 | 45 | 2005 |
Clarifying the Risk of Lung Disease in SZ α1-antitrypsin Deficiency AN Franciosi, BD Hobbs, OJ McElvaney, K Molloy, C Hersh, L Clarke, ... American Journal of Respiratory and Critical Care Medicine, 2020 | 42 | 2020 |
Anti-apoptotic effects of Z α1-antitrypsin in human bronchial epithelial cells CM Greene, SDW Miller, TP Carroll, IK Oglesby, F Ahmed, M O'Mahony, ... European Respiratory Journal 35 (5), 1155-1163, 2010 | 36 | 2010 |