Sucrose phosphorylase and related enzymes in glycoside hydrolase family 13: discovery, application and engineering J Franceus, T Desmet International Journal of Molecular Sciences 21 (7), 2526, 2020 | 62 | 2020 |
Insertions and deletions in protein evolution and engineering S Savino, T Desmet, J Franceus Biotechnology Advances 60, 108010, 2022 | 37 | 2022 |
Synthesis of Potent and Selective HDAC6 Inhibitors Bearing a Cyclohexane‐or Cycloheptane‐Annulated 1, 5‐Benzothiazepine Scaffold R De Vreese, L Galle, Y Depetter, J Franceus, T Desmet, K Van Hecke, ... Chemistry–A European Journal 23 (1), 128-136, 2017 | 35 | 2017 |
Glucosylglycerate phosphorylase, an enzyme with novel specificity involved in compatible solute metabolism J Franceus, D Pinel, T Desmet Applied and environmental microbiology 83 (19), e01434-17, 2017 | 31 | 2017 |
Rational design of an improved transglucosylase for production of the rare sugar nigerose J Franceus, S Dhaene, H Decadt, J Vandepitte, J Caroen, ... Chemical Communications 55 (31), 4531-4533, 2019 | 28 | 2019 |
Thermostable alpha-glucan phosphorylases: characteristics and industrial applications Z Ubiparip, K Beerens, J Franceus, R Vercauteren, T Desmet Applied microbiology and biotechnology 102, 8187-8202, 2018 | 28 | 2018 |
Exploring the sequence diversity in glycoside hydrolase family 13_18 reveals a novel glucosylglycerol phosphorylase J Franceus, L Decuyper, M D’hooghe, T Desmet Applied microbiology and biotechnology 102, 3183-3191, 2018 | 19 | 2018 |
Correlated positions in protein evolution and engineering J Franceus, T Verhaeghe, T Desmet Journal of Industrial Microbiology and Biotechnology 44 (4-5), 687-695, 2017 | 19 | 2017 |
Diastereoselective synthesis of 3-acetoxy-4-(3-aryloxiran-2-yl) azetidin-2-ones and their transformation into 3, 4-oxolane-fused bicyclic β-lactams N Piens, S De Craene, J Franceus, K Mollet, K Van Hecke, T Desmet, ... Organic & biomolecular chemistry 14 (47), 11279-11288, 2016 | 17 | 2016 |
β-Glucan phosphorylases in carbohydrate synthesis Z Ubiparip, M De Doncker, K Beerens, J Franceus, T Desmet Applied Microbiology and Biotechnology 105 (10), 4073-4087, 2021 | 15 | 2021 |
Structural Comparison of a Promiscuous and a Highly Specific Sucrose 6F-Phosphate Phosphorylase J Franceus, N Capra, T Desmet, AMWH Thunnissen International Journal of Molecular Sciences 20 (16), 3906, 2019 | 14 | 2019 |
Discovery of a kojibiose hydrolase by analysis of specificity-determining correlated positions in glycoside hydrolase family 65 E De Beul, A Jongbloet, J Franceus, T Desmet Molecules 26 (20), 6321, 2021 | 13 | 2021 |
Chemoenzymatic Approach toward the Synthesis of 3-O-(α/β)-Glucosylated 3-Hydroxy-β-lactams L Decuyper, J Franceus, S Dhaene, M Debruyne, K Vandoorne, N Piens, ... ACS omega 3 (11), 15235-15245, 2018 | 12 | 2018 |
Building mutational bridges between carbohydrate-active enzymes J Franceus, J Lormans, T Desmet Current Opinion in Biotechnology 78, 102804, 2022 | 9 | 2022 |
Identification of mercaptoacetamide-based HDAC6 inhibitors via a lean inhibitor strategy: screening, synthesis, and biological evaluation S Geurs, D Clarisse, F Baele, J Franceus, T Desmet, K De Bosscher, ... Chemical Communications 58 (42), 6239-6242, 2022 | 9 | 2022 |
Engineering of a Thermostable Biocatalyst for the Synthesis of 2‐O‐Glucosylglycerol J Franceus, Z Ubiparip, K Beerens, T Desmet ChemBioChem 22 (18), 2777-2782, 2021 | 9 | 2021 |
Exploration of GH94 sequence space for enzyme discovery reveals a novel Glucosylgalactose phosphorylase specificity M De Doncker, C De Graeve, J Franceus, K Beerens, V Křen, H Pelantová, ... Chembiochem 22 (23), 3319-3325, 2021 | 8 | 2021 |
Evolution of Phosphorylases from N-Acetylglucosaminide Hydrolases in Family GH3 J Franceus, J Lormans, L Cools, M D’hooghe, T Desmet ACS Catalysis 11 (10), 6225-6233, 2021 | 8 | 2021 |
Synthesis, trehalase hydrolytic resistance and inhibition properties of 4-and 6-substituted trehalose derivatives S Dhaene, J Van der Eycken, K Beerens, J Franceus, T Desmet, J Caroen Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 1964-1989, 2020 | 7 | 2020 |
Assessment of the trifluoromethyl ketone functionality as an alternative zinc-binding group for selective HDAC6 inhibition Y Depetter, S Geurs, FV Bussche, R De Vreese, J Franceus, T Desmet, ... MedChemComm 9 (6), 1011-1016, 2018 | 6 | 2018 |