Reconstructing and deconstructing agonist-induced activation of integrin αIIbβ3 J Han, CJ Lim, N Watanabe, A Soriani, B Ratnikov, DA Calderwood, ... Current Biology 16 (18), 1796-1806, 2006 | 552 | 2006 |
RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences HS Lee, CJ Lim, W Puzon-McLaughlin, SJ Shattil, MH Ginsberg Journal of Biological Chemistry 284 (8), 5119-5127, 2009 | 388 | 2009 |
Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common β1 chain A Luque, M Gómez, W Puzon, Y Takada, F Sánchez-Madrid, C Cabanas Journal of Biological Chemistry 271 (19), 11067-11075, 1996 | 338 | 1996 |
Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin αvβ3 XP Zhang, T Kamata, K Yokoyama, W Puzon-McLaughlin, Y Takada Journal of Biological Chemistry 273 (13), 7345-7350, 1998 | 309 | 1998 |
RGD-independent binding of integrin α9β1 to the ADAM-12 and-15 disintegrin domains mediates cell-cell interaction K Eto, W Puzon-McLaughlin, D Sheppard, A Sehara-Fujisawa, XP Zhang, ... Journal of Biological Chemistry 275 (45), 34922-34930, 2000 | 295 | 2000 |
Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies Y Takada, W Puzon Journal of Biological Chemistry 268 (23), 17597-17601, 1993 | 282 | 1993 |
Functional classification of ADAMs based on a conserved motif for binding to integrin α9β1: implications for sperm-egg binding and other cell interactions K Eto, C Huet, T Tarui, S Kupriyanov, HZ Liu, W Puzon-McLaughlin, ... Journal of Biological Chemistry 277 (20), 17804-17810, 2002 | 248 | 2002 |
Identification of putative ligand binding sites within I domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29) T Kamata, W Puzon, Y Takada Journal of Biological Chemistry 269 (13), 9659-9663, 1994 | 237 | 1994 |
A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques. Y Takada, J Ylänne, D Mandelman, W Puzon, MH Ginsberg The Journal of cell biology 119 (4), 913-921, 1992 | 163 | 1992 |
Changing ligand specificities of αvβ1 and αvβ3 integrins by swapping a short diverse sequence of the β subunit J Takagi, T Kamata, J Meredith, W Puzon-McLaughlin, Y Takada Journal of Biological Chemistry 272 (32), 19794-19800, 1997 | 162 | 1997 |
Identification of putative ligand-binding sites of the integrin α4β1 (VLA-4, CD49d/CD29) T Kamata, W Puzon, Y Takada Biochemical Journal 305 (3), 945-951, 1995 | 161 | 1995 |
Induction of experimental bone metastasis in mice by transfection of integrin alpha 4 beta 1 into tumor cells. N Matsuura, W Puzon-McLaughlin, A Irie, Y Morikawa, K Kakudo, ... The American journal of pathology 148 (1), 55, 1996 | 153 | 1996 |
Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin α5β1 AP Mould, AN Garratt, W Puzon-McLaughlin, Y Takada, MJ Humphries Biochemical Journal 331 (3), 821-828, 1998 | 144 | 1998 |
Differential regulation of Rho GTPases by β1 and β3 integrins: the role of an extracellular domain of integrin in intracellular signaling H Miao, S Li, YL Hu, S Yuan, Y Zhao, BPC Chen, W Puzon-McLaughlin, ... Journal of cell science 115 (10), 2199-2206, 2002 | 128 | 2002 |
Critical amino acid residues for ligand binding are clustered in a predicted beta‐turn of the third N‐terminal repeat in the integrin alpha 4 and alpha 5 subunits. A Irie, T Kamata, W Puzon‐McLaughlin, Y Takada The EMBO Journal 14 (22), 5550-5556, 1995 | 124 | 1995 |
Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin αIIbβ3 W Puzon-McLaughlin, T Kamata, Y Takada Journal of Biological Chemistry 275 (11), 7795-7802, 2000 | 122 | 2000 |
Critical residues for ligand binding in an I domain-like structure of the integrin β1 subunit W Puzon-McLaughlin, Y Takada Journal of Biological Chemistry 271 (34), 20438-20443, 1996 | 111 | 1996 |
Critical cysteine residues for regulation of integrin alphaIIbbeta3 are clustered in the epidermal growth factor domains of the beta3 subunit T Kamata, H Ambo, W Puzon-McLaughlin, KK Tieu, M Handa, Y Ikeda, ... Biochemical Journal 378 (3), 1079-1082, 2004 | 76 | 2004 |
The role of the CPNKEKEC sequence in the β2 subunit I domain in regulation of integrin αLβ2 (LFA-1) T Kamata, KK Tieu, T Tarui, W Puzon-McLaughlin, N Hogg, Y Takada The Journal of Immunology 168 (5), 2296-2301, 2002 | 74 | 2002 |
Structural basis of integrin-mediated signal transduction Y Takada, T Kamata, A Irie, W Puzon-McLaughlin, XP Zhang Matrix biology 16 (4), 143-151, 1997 | 67 | 1997 |