| Pyroptosis versus necroptosis: similarities, differences, and crosstalk D Frank, JE Vince Cell Death & Differentiation 26 (1), 99-114, 2019 | 821 | 2019 |
| MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis AL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, ... Nature communications 11 (1), 3151, 2020 | 232 | 2020 |
| CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer E Sanij, KM Hannan, J Xuan, S Yan, JE Ahern, AS Trigos, N Brajanovski, ... Nature communications 11 (1), 2641, 2020 | 120 | 2020 |
| The pyroptotic cell death effector gasdermin D is activated by gout-associated uric acid crystals but is dispensable for cell death and IL-1β release M Rashidi, DS Simpson, A Hempel, D Frank, E Petrie, A Vince, R Feltham, ... The Journal of Immunology 203 (3), 736-748, 2019 | 107 | 2019 |
| Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model Z Erlich, I Shlomovitz, L Edry-Botzer, H Cohen, D Frank, H Wang, AM Lew, ... Nature immunology 20 (4), 397-406, 2019 | 97 | 2019 |
| Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK A Geissler, F Haun, DO Frank, K Wieland, MM Simon, M Idzko, RJ Davis, ... Cell Death & Differentiation 20 (10), 1317-1329, 2013 | 83 | 2013 |
| Activated MLKL attenuates autophagy following its translocation to intracellular membranes D Frank, DL Vaux, JM Murphy, JE Vince, LM Lindqvist Journal of cell science 132 (5), jcs220996, 2019 | 58 | 2019 |
| Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion LM Lindqvist, D Frank, K McArthur, TA Dite, M Lazarou, JS Oakhill, BT Kile, ... Cell Death & Differentiation 25 (4), 784-796, 2018 | 53 | 2018 |
| The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation SL Vijayaraj, R Feltham, M Rashidi, D Frank, Z Liu, DS Simpson, G Ebert, ... Nature Communications 12 (1), 2713, 2021 | 50 | 2021 |
| The potential of targeting ribosome biogenesis in high-grade serous ovarian cancer S Yan, D Frank, J Son, KM Hannan, RD Hannan, KT Chan, RB Pearson, ... International journal of molecular sciences 18 (1), 210, 2017 | 29 | 2017 |
| Caspase‐8‐driven apoptotic and pyroptotic crosstalk causes cell death and IL‐1β release in X‐linked inhibitor of apoptosis (XIAP) deficiency SA Hughes, M Lin, A Weir, B Huang, L Xiong, NK Chua, J Pang, ... The EMBO Journal 42 (5), e110468, 2023 | 21 | 2023 |
| A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation SE Garnish, KR Martin, M Kauppi, VE Jackson, R Ambrose, VV Eng, ... Nature Communications 14 (1), 6046, 2023 | 4 | 2023 |
| Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death D Frank, SE Garnish, JJ Sandow, A Weir, L Liu, E Clayer, L Meza, ... Iscience 25 (7), 2022 | 4 | 2022 |
| ZC3H12C expression in dendritic cells is necessary to prevent lymphadenopathy of skin‐draining lymph nodes E Clayer, D Frank, H Anderton, S Zhang, A Kueh, V Heim, SL Nutt, ... Immunology and Cell Biology 100 (3), 160-173, 2022 | 4 | 2022 |
| Inhibition of RNA polymerase I transcription activates targeted DNA damage response and enhances the efficacy of PARP inhibitors in high-grade serous ovarian cancer E Sanij, KM Hannan, S Yan, J Xuan, JE Ahern, KT Chan, J Son, ... bioRxiv, 621623, 2019 | 2 | 2019 |
| Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth D Frank, M Bergamasco, MJ Mlodzianoski, A Kueh, E Tsui, C Hall, ... Elife 12, RP90796, 2023 | | 2023 |
| The inflammasome-activated cytokine IL-1β is targeted for ubiquitylation and proteasomal degradation to limit its inflammatory potential SL Vijayaraj, R Feltham, M Rashidi, D Frank, Z Liu, DS Simpson, G Ebert, ... bioRxiv, 2021.03. 15.435390, 2021 | | 2021 |
