Manganese and its role in Parkinson’s disease: from transport to neuropathology M Aschner, KM Erikson, EH Hernández, R Tjalkens Neuromolecular medicine 11, 252-266, 2009 | 342 | 2009 |
Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity KS Kirkley, KA Popichak, MF Afzali, ME Legare, RB Tjalkens Journal of neuroinflammation 14, 1-18, 2017 | 308 | 2017 |
Toxicological and pathophysiological roles of reactive oxygen and nitrogen species RA Roberts, RA Smith, S Safe, C Szabo, RB Tjalkens, FM Robertson Toxicology 276 (2), 85-94, 2010 | 284 | 2010 |
Nuclear receptor 4A (NR4A) family–orphans no more S Safe, UH Jin, B Morpurgo, A Abudayyeh, M Singh, RB Tjalkens The Journal of steroid biochemistry and molecular biology 157, 48-60, 2016 | 190 | 2016 |
Manganese-induced neurotoxicity: the role of astroglial-derived nitric oxide in striatal interneuron degeneration X Liu, KA Sullivan, JE Madl, M Legare, RB Tjalkens Toxicological Sciences 91 (2), 521-531, 2006 | 171 | 2006 |
Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intracerebroventricular injection SL Hammond, AN Leek, EH Richman, RB Tjalkens PloS one 12 (12), e0188830, 2017 | 152 | 2017 |
The role of docosahexaenoic acid in mediating mitochondrial membrane lipid oxidation and apoptosis in colonocytes Y Ng, R Barhoumi, RB Tjalkens, YY Fan, S Kolar, N Wang, JR Lupton, ... Carcinogenesis 26 (11), 1914-1921, 2005 | 122 | 2005 |
Inflammatory activation of microglia and astrocytes in manganese neurotoxicity RB Tjalkens, KA Popichak, KA Kirkley Neurotoxicity of Metals, 159-181, 2017 | 121 | 2017 |
Age-dependent susceptibility to manganese-induced neurological dysfunction JA Moreno, EC Yeomans, KM Streifel, BL Brattin, RJ Taylor, RB Tjalkens Toxicological Sciences 112 (2), 394-404, 2009 | 113 | 2009 |
Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells SO Lee, X Li, E Hedrick, UH Jin, RB Tjalkens, DS Backos, L Li, Y Zhang, ... Molecular endocrinology 28 (10), 1729-1739, 2014 | 110 | 2014 |
α, β-Unsaturated Aldehydes Increase GlutathioneS-Transferase mRNA and Protein: Correlation with Activation of the Antioxidant Response Element RB Tjalkens, SW Luckey, DJ Kroll, DR Petersen Archives of Biochemistry and Biophysics 359 (1), 42-50, 1998 | 92 | 1998 |
Subunit composition and domain structure of the Spo0A sporulation transcription factor of Bacillus subtilis JK Grimsley, RB Tjalkens, MA Strauch, TH Bird, GB Spiegelman, ... Journal of Biological Chemistry 269 (24), 16977-16982, 1994 | 92 | 1994 |
SARS-CoV-2 infection, neuropathogenesis and transmission among deer mice: Implications for spillback to New World rodents A Fagre, J Lewis, M Eckley, S Zhan, SM Rocha, NR Sexton, B Burke, ... PLoS pathogens 17 (5), e1009585, 2021 | 91 | 2021 |
Formation and export of the glutathione conjugate of 4-hydroxy-2, 3-E-nonenal (4-HNE) in hepatoma cells RB Tjalkens, LW Cook, DR Petersen Archives of biochemistry and biophysics 361 (1), 113-119, 1999 | 88 | 1999 |
The Nurr1 activator 1, 1-bis (3′-indolyl)-1-(p-chlorophenyl) methane blocks inflammatory gene expression in BV-2 microglial cells by inhibiting nuclear factor κB BR De Miranda, KA Popichak, SL Hammond, BA Jorgensen, AT Phillips, ... Molecular pharmacology 87 (6), 1021-1034, 2015 | 86 | 2015 |
Manganese potentiates lipopolysaccharide-induced expression of NOS2 in C6 glioma cells through mitochondrial-dependent activation of nuclear factor kappaB R Barhoumi, J Faske, X Liu, RB Tjalkens Molecular brain research 122 (2), 167-179, 2004 | 83 | 2004 |
Infection with mosquito-borne alphavirus induces selective loss of dopaminergic neurons, neuroinflammation and widespread protein aggregation CM Bantle, AT Phillips, RJ Smeyne, SM Rocha, KE Olson, RB Tjalkens npj Parkinson's Disease 5 (1), 20, 2019 | 82 | 2019 |
Association of glutathioneS-transferase isozyme-specific induction and lipid peroxidation in two inbred strains of mice subjected to chronic dietary iron overload RB Tjalkens, LG Valerio Jr, YC Awasthi, DR Petersen Toxicology and applied pharmacology 151 (1), 174-181, 1998 | 72 | 1998 |
Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson’s disease BR De Miranda, JA Miller, RJ Hansen, PJ Lunghofer, S Safe, ... Journal of Pharmacology and Experimental Therapeutics 345 (1), 125-138, 2013 | 71 | 2013 |
Manganese potentiates nuclear factor‐κB‐dependent expression of nitric oxide synthase 2 in astrocytes by activating soluble guanylate cyclase and extracellular responsive … JA Moreno, KA Sullivan, DL Carbone, WH Hanneman, RB Tjalkens Journal of neuroscience research 86 (9), 2028-2038, 2008 | 69 | 2008 |