| A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic T Shapira, IA Monreal, SP Dion, DW Buchholz, B Imbiakha, AD Olmstead, ... Nature 605 (7909), 340-348, 2022 | 156 | 2022 |
| The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction NJ Ronaghan, J Shang, V Iablokov, R Zaheer, P Colarusso, S Dion, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 311 (3 …, 2016 | 35 | 2016 |
| Discovery and development of TMPRSS6 inhibitors modulating hepcidin levels in human hepatocytes F Béliveau, A Tarkar, SP Dion, A Désilets, MG Ghinet, PL Boudreault, ... Cell Chemical Biology 26 (11), 1559-1572. e9, 2019 | 32 | 2019 |
| Modulating the selectivity of matriptase-2 inhibitors with unnatural amino acids C St-Georges, A Désilets, F Béliveau, M Ghinet, SP Dion, É Colombo, ... European Journal of Medicinal Chemistry 129, 110-123, 2017 | 25 | 2017 |
| Inhibitors of type II transmembrane serine proteases in the treatment of diseases of the respiratory tract–A review of patent literature A Murza, SP Dion, PL Boudreault, A Désilets, R Leduc, É Marsault Expert Opinion on Therapeutic Patents 30 (11), 807-824, 2020 | 22 | 2020 |
| Functional diversity of TMPRSS6 isoforms and variants expressed in hepatocellular carcinoma cell lines SP Dion, F Béliveau, LP Morency, A Désilets, R Najmanovich, R Leduc Scientific Reports 8 (1), 12562, 2018 | 19 | 2018 |
| A novel highly potent inhibitor of TMPRSS2-like proteases blocks SARS-CoV-2 variants of concern and is broadly protective against infection and mortality in mice T Shapira, IA Monreal, SP Dion, M Jager, A Désilets, AD Olmstead, ... bioRxiv, 2021.05. 03.442520, 2021 | 18 | 2021 |
| Transcriptome analysis reveals TMPRSS6 isoforms with distinct functionalities SP Dion, F Béliveau, A Désilets, MG Ghinet, R Leduc Journal of Cellular and Molecular Medicine 22 (4), 2498-2509, 2018 | 15 | 2018 |
| Signaling pathways induced by serine proteases to increase intestinal epithelial barrier function KA Lahey, NJ Ronaghan, J Shang, SP Dion, A Désilets, R Leduc, ... PLoS One 12 (7), e0180259, 2017 | 12 | 2017 |
| Discovery and development of TMPRSS6 inhibitors modulating hepcidin levels in human hepatocytes. Cell Chem Biol. 2019; 26 (11): 1559–72. e9 F Béliveau, A Tarkar, SP Dion, A Désilets, MG Ghinet, PL Boudreault | 3 | |
| Functionally impaired isoforms regulate TMPRSS6 proteolytic activity SP Dion, A Désilets, G Lemieux, R Leduc Plos one 17 (8), e0273825, 2022 | 2 | 2022 |
| Expression et rôle des isoformes de TMPRSS6, une protéase impliquée dans la régulation du fer S Dion Université de Sherbrooke, 2022 | | 2022 |
