Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1–mediated lipogenesis F Geng, X Cheng, X Wu, JY Yoo, C Cheng, JY Guo, X Mo, P Ru, B Hurwitz, ... Clinical Cancer Research 22 (21), 5337-5348, 2016 | 276 | 2016 |
Glucose-mediated N-glycosylation of SCAP is essential for SREBP-1 activation and tumor growth C Cheng, P Ru, F Geng, J Liu, JY Yoo, X Wu, X Cheng, V Euthine, P Hu, ... Cancer cell 28 (5), 569-581, 2015 | 251 | 2015 |
VEGF-specific short hairpin RNA–expressing oncolytic adenovirus elicits potent inhibition of angiogenesis and tumor growth JY Yoo, JH Kim, YG Kwon, EC Kim, NK Kim, HJ Choi, CO Yun Molecular Therapy 15 (2), 295-302, 2007 | 181 | 2007 |
MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme SS Suh, JY Yoo, GJ Nuovo, YJ Jeon, S Kim, TJ Lee, T Kim, A Bakàcs, ... Proceedings of the National Academy of Sciences 109 (14), 5316-5321, 2012 | 162 | 2012 |
RNA Nanoparticle-Based Targeted Therapy for Glioblastoma through Inhibition of Oncogenic miR-21 CCM Lee TJ, Yoo JY, Shu D, Li H, Zhang J, Yu JG, Jaime-Ramirez AC, Acunzo M ... Molecular Therapy, 2017 | 137 | 2017 |
PRMT5–PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells YK Banasavadi-Siddegowda, L Russell, E Frair, VA Karkhanis, T Relation, ... Oncogene 36 (2), 263-274, 2017 | 122 | 2017 |
Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virus H Uchida, M Marzulli, K Nakano, WF Goins, J Chan, CS Hong, ... Molecular Therapy 21 (3), 561-569, 2013 | 122 | 2013 |
Short hairpin RNA-expressing oncolytic adenovirus-mediated inhibition of IL-8: effects on antiangiogenesis and tumor growth inhibition JY Yoo, JH Kim, J Kim, JH Huang, SN Zhang, YA Kang, H Kim, CO Yun Gene therapy 15 (9), 635-651, 2008 | 119 | 2008 |
Effect of decorin on overcoming the extracellular matrix barrier for oncolytic virotherapy IK Choi, YS Lee, JY Yoo, AR Yoon, H Kim, DS Kim, DG Seidler, JH Kim, ... Gene therapy 17 (2), 190-201, 2010 | 117 | 2010 |
Optimizing DC vaccination by combination with oncolytic adenovirus coexpressing IL-12 and GM-CSF SN Zhang, IK Choi, JH Huang, JY Yoo, KJ Choi, CO Yun Molecular Therapy 19 (8), 1558-1568, 2011 | 110 | 2011 |
RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model TJ Lee, F Haque, D Shu, JY Yoo, H Li, RA Yokel, C Horbinski, TH Kim, ... Oncotarget 6 (17), 14766, 2015 | 100 | 2015 |
Feedback loop regulation of SCAP/SREBP-1 by miR-29 modulates EGFR signaling-driven glioblastoma growth P Ru, P Hu, F Geng, X Mo, C Cheng, JY Yoo, X Cheng, X Wu, JY Guo, ... Cell reports 16 (6), 1527-1535, 2016 | 86 | 2016 |
The impact of macrophage-and microglia-secreted TNFα on oncolytic HSV-1 therapy in the glioblastoma tumor microenvironment WH Meisen, ES Wohleb, AC Jaime-Ramirez, C Bolyard, JY Yoo, ... Clinical Cancer Research 21 (14), 3274-3285, 2015 | 86 | 2015 |
An oncolytic herpesvirus expressing E-cadherin improves survival in mouse models of glioblastoma B Xu, R Ma, L Russell, JY Yoo, J Han, H Cui, P Yi, J Zhang, H Nakashima, ... Nature biotechnology 37 (1), 45-54, 2019 | 81 | 2019 |
Bortezomib-induced unfolded protein response increases oncolytic HSV-1 replication resulting in synergistic antitumor effects JY Yoo, BS Hurwitz, C Bolyard, JG Yu, J Zhang, K Selvendiran, KS Rath, ... Clinical cancer research 20 (14), 3787-3798, 2014 | 78 | 2014 |
FHIT suppresses epithelial-mesenchymal transition (EMT) and metastasis in lung cancer through modulation of microRNAs SS Suh, JY Yoo, R Cui, B Kaur, K Huebner, TK Lee, RI Aqeilan, CM Croce PLoS genetics 10 (10), e1004652, 2014 | 75 | 2014 |
Bortezomib treatment sensitizes oncolytic HSV-1–treated tumors to NK cell immunotherapy JY Yoo, AC Jaime-Ramirez, C Bolyard, H Dai, T Nallanagulagari, ... Clinical Cancer Research 22 (21), 5265-5276, 2016 | 74 | 2016 |
Suicide cancer gene therapy using pore-forming toxin, streptolysin O WS Yang, SO Park, AR Yoon, JY Yoo, MK Kim, CO Yun, CW Kim Molecular cancer therapeutics 5 (6), 1610-1619, 2006 | 74 | 2006 |
Tumor suppression by apoptotic and anti‐angiogenic effects of mortalin‐targeting adeno‐oncolytic virus JY Yoo, J Ryu, R Gao, T Yaguchi, SC Kaul, R Wadhwa, CO Yun The journal of gene medicine 12 (7), 586-595, 2010 | 71 | 2010 |
Efficacy of onalespib, a long-acting second-generation HSP90 inhibitor, as a single agent and in combination with temozolomide against malignant gliomas A Canella, AM Welker, JY Yoo, J Xu, FS Abas, D Kesanakurti, ... Clinical Cancer Research 23 (20), 6215-6226, 2017 | 69 | 2017 |