关注
Rajagopal Murugan
Rajagopal Murugan
Assistant Professor, Leiden University Center for Infectious Diseases, LUMC, Leiden, The Netherlands
在 lumc.nl 的电子邮件经过验证
标题
引用次数
引用次数
年份
Human cerebrospinal fluid monoclonal N -methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis
J Kreye, NK Wenke, M Chayka, J Leubner, R Murugan, N Maier, B Jurek, ...
Brain 139 (10), 2641-2652, 2016
2692016
Clonal selection drives protective memory B cell responses in controlled human malaria infection
R Murugan, L Buchauer, G Triller, C Kreschel, G Costa, ...
Science immunology 3 (20), eaap8029, 2018
1472018
Natural parasite exposure induces protective human anti-malarial antibodies
G Triller, SW Scally, G Costa, M Pissarev, C Kreschel, A Bosch, E Marois, ...
Immunity 47 (6), 1197-1209. e10, 2017
1442017
Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope
K Imkeller, SW Scally, A Bosch, GP Martí, G Costa, G Triller, R Murugan, ...
Science 360 (6395), 1358-1362, 2018
952018
Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection
SW Scally, R Murugan, A Bosch, G Triller, G Costa, B Mordmüller, ...
Journal of Experimental Medicine 215 (1), 63-75, 2018
852018
Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs
R Murugan, SW Scally, G Costa, G Mustafa, E Thai, T Decker, A Bosch, ...
Nature medicine 26 (7), 1135-1145, 2020
792020
Direct high‐throughput amplification and sequencing of immunoglobulin genes from single human B cells
R Murugan, K Imkeller, CE Busse, H Wardemann
European journal of immunology 45 (9), 2698, 2015
462015
A putative low-molecular-mass penicillin-binding protein (PBP) of Mycobacterium smegmatis exhibits prominent physiological characteristics of DD-carboxypeptidase and beta-lactamase
A Bansal, D Kar, RA Murugan, S Mallick, M Dutta, SD Pandey, ...
Microbiology 161 (5), 1081-1091, 2015
362015
A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity
E Thai, G Costa, A Weyrich, R Murugan, D Oyen, Y Flores-Garcia, K Prieto, ...
Journal of Experimental Medicine 217 (11), e20200061, 2020
222020
From human antibody structure and function towards the design of a novel Plasmodium falciparum circumsporozoite protein malaria vaccine
H Wardemann, R Murugan
Current opinion in immunology 53, 119-123, 2018
152018
From multiplex serology to serolomics—A novel approach to the antibody response against the SARS-CoV-2 proteome
J Butt, R Murugan, T Hippchen, S Olberg, M van Straaten, H Wardemann, ...
Viruses 13 (5), 749, 2021
142021
Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodies
OE Oludada, G Costa, C Burn Aschner, AS Obraztsova, K Prieto, ...
EMBO Molecular Medicine 15 (6), e17454, 2023
82023
Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model
J Ludwig, SW Scally, G Costa, S Hoffmann, R Murugan, J Lossin, K Prieto, ...
npj Vaccines 8 (1), 52, 2023
82023
High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire
I Kucharska, Š Binter, R Murugan, SW Scally, J Ludwig, K Prieto, E Thai, ...
Plos Pathogens 18 (11), e1010999, 2022
72022
Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein
E Thai, R Murugan, Š Binter, CB Aschner, K Prieto, A Kassardjian, ...
Cell Reports 42 (11), 2023
42023
Affinity-independent memory B cell origin of the early antibody-secreting cell response in naive individuals upon SARS-CoV-2 vaccination
Z Li, A Obraztsova, F Shang, OE Oludada, J Malapit, K Busch, ...
Immunity, 2024
2024
Somatic hypermutation-mediated paratope flexibility improves the cross-reactivity of human malaria antibodies
R Murugan, A Hanke, OE Oludada, G Costa, Y Flores-Garcia, G Mustafa, ...
bioRxiv, 2024.07. 24.604858, 2024
2024
High affinity antibodies against the sars-cov-2 receptor binding domain
H Wardemann, R Murugan, R Bartenschlager, H Kim
WO Patent WO2023156187A1, 2023
2023
Memory B cells dominate the early antibody-secreting cell response to SARS-CoV-2 mRNA vaccination in naive individuals independently of their antibody affinity
Z Li, A Obraztsova, F Shang, OE Oludada, J Malapit, K Busch, ...
bioRxiv, 2023.12. 01.569639, 2023
2023
PLASMODIUM ANTIBODIES
H Wardemann, R Murugan, T Decker, E Levashina, G Costa, J Julien, ...
US Patent App. 17/624,046, 2022
2022
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