| Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma G Agliardi, AR Liuzzi, A Hotblack, D De Feo, N Núñez, CL Stowe, ... Nature communications 12 (1), 444, 2021 | 184 | 2021 |
| Regulatory T cells restrain interleukin-2-and Blimp-1-dependent acquisition of cytotoxic function by CD4+ T cells A Śledzińska, MV de Mucha, K Bergerhoff, A Hotblack, DF Demane, ... Immunity 52 (1), 151-166. e6, 2020 | 175 | 2020 |
| Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin CL Stowe, TA Burley, H Allan, M Vinci, G Kramer-Marek, DM Ciobota, ... Elife 8, e45801, 2019 | 52 | 2019 |
| Tumor-resident dendritic cells and macrophages modulate the accumulation of TCR-engineered T cells in melanoma A Hotblack, A Holler, A Piapi, S Ward, HJ Stauss, CL Bennett Molecular Therapy 26 (6), 1471-1481, 2018 | 25 | 2018 |
| Tunable control of CAR T cell activity through tetracycline mediated disruption of protein–protein interaction A Hotblack, EK Kokalaki, MJ Palton, GWK Cheung, IP Williams, ... Scientific Reports 11 (1), 21902, 2021 | 14 | 2021 |
| Dendritic cells cross-present immunogenic lentivector-encoded antigen from transduced cells to prime functional T cell immunity A Hotblack, S Seshadri, L Zhang, S Hamrang-Yousefi, R Chakraverty, ... Molecular Therapy 25 (2), 504-511, 2017 | 9 | 2017 |
| 4-1BB ligand activates bystander dendritic cells to enhance immunization in trans DC Macdonald, A Hotblack, S Akbar, G Britton, MK Collins, ... The Journal of Immunology 193 (10), 5056-5064, 2014 | 8 | 2014 |
| AKT inhibition generates potent polyfunctional clinical grade AUTO1 CAR T-cells, enhancing function and survival V Mehra, G Agliardi, JDA Pinto, MS Shafat, AC Garai, L Green, A Hotblack, ... Journal for Immunotherapy of Cancer 11 (9), 2023 | 6 | 2023 |
| P1460: SAFETY AND EFFICACY FINDINGS OF AUTO1, A FAST-OFF RATE CD19 CAR, IN RELAPSED/REFRACTORY PRIMARY CNS LYMPHOMA C Roddie, J Dias, M O’Reilly, L Green, M Vaughan, G Agliardi, J Garcia, ... HemaSphere 6, 1342-1343, 2022 | 2 | 2022 |
| IMMU-16. Next-generation CAR T-cells targeting IL13RA2 and secreting IL-15 achieve durable tumour clearance in pre-clinical model of diffuse midline glioma A Hotblack, P Wawrzyniecka, GWK Cheng, F Nannini, M Pule, K Straathof Neuro-Oncology 24 (Suppl 1), i85, 2022 | 2 | 2022 |
| Fine-tuning CARs for best performance A Hotblack, K Straathof Cancer Cell 40 (1), 11-13, 2022 | 2 | 2022 |
| Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy A Holler, M Zech, S Ghorashian, R Pike, A Hotblack, P Veliça, SA Xue, ... haematologica 101 (4), 482, 2016 | 2 | 2016 |
| Characterising the role of dendritic cells in TCR gene therapy AC Hotblack UCL (University College London), 2017 | 1 | 2017 |
| Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein–Protein Interaction R Jha, A Kinna, A Hotblack, R Bughda, A Bulek, I Gannon, T Ilca, C Allen, ... ACS Chemical Biology, 2024 | | 2024 |
| IMMU-16. INTRA-TUMOURAL IL-12 DELIVERY ENABLES CAR T-CELL IMMUNOTHERAPY FOR HIGH-GRADE GLIOMA G Agliardi, AR Liuzzi, A Hotblack, D De Feo, N Nunez, E Friebel, ... Neuro-oncology 22 (Suppl 3), iii363, 2020 | | 2020 |
