Induction of myelinating oligodendrocytes in human cortical spheroids M Madhavan, ZS Nevin, HE Shick, E Garrison, C Clarkson-Paredes, ... Nature methods 15 (9), 700-706, 2018 | 300 | 2018 |
Accumulation of 8, 9-unsaturated sterols drives oligodendrocyte formation and remyelination Z Hubler, D Allimuthu, I Bederman, MS Elitt, M Madhavan, KC Allan, ... Nature 560 (7718), 372-376, 2018 | 209 | 2018 |
Signaling through ERK1/2 controls myelin thickness during myelin repair in the adult central nervous system SL Fyffe-Maricich, A Schott, M Karl, J Krasno, RH Miller Journal of Neuroscience 33 (47), 18402-18408, 2013 | 105 | 2013 |
Nanocatalytic activity of clean-surfaced, faceted nanocrystalline gold enhances remyelination in animal models of multiple sclerosis AP Robinson, JZ Zhang, HE Titus, M Karl, M Merzliakov, AR Dorfman, ... Scientific reports 10 (1), 1936, 2020 | 82 | 2020 |
Astrocytes are required for oligodendrocyte survival and maintenance of myelin compaction and integrity R Tognatta, MT Karl, SL Fyffe-Maricich, A Popratiloff, ED Garrison, ... Frontiers in cellular neuroscience 14, 74, 2020 | 57 | 2020 |
Translational control of myelin basic protein expression by ERK2 MAP kinase regulates timely remyelination in the adult brain K Michel, T Zhao, M Karl, K Lewis, SL Fyffe-Maricich Journal of Neuroscience 35 (20), 7850-7865, 2015 | 56 | 2015 |
Invariant synapse density and neuronal connectivity scaling in primate neocortical evolution CC Sherwood, SB Miller, M Karl, CD Stimpson, KA Phillips, B Jacobs, ... Cerebral Cortex 30 (10), 5604-5615, 2020 | 51 | 2020 |
Apoptosis of oligodendrocytes during early development delays myelination and impairs subsequent responses to demyelination AV Caprariello, CE Batt, I Zippe, RR Romito-DiGiacomo, M Karl, RH Miller Journal of Neuroscience 35 (41), 14031-14041, 2015 | 40 | 2015 |
Loss of HDAC11 ameliorates clinical symptoms in a multiple sclerosis mouse model L Sun, E Telles, M Karl, F Cheng, N Luetteke, EM Sotomayor, RH Miller, ... Life science alliance 1 (5), 2018 | 39 | 2018 |
Extension of the neuroprotective time window for thiazolidinediones in ischemic stroke is dependent on time of reperfusion J Gamboa, DA Blankenship, JP Niemi, GE Landreth, M Karl, E Hilow, ... Neuroscience 170 (3), 846-857, 2010 | 36 | 2010 |
CNS disease diminishes the therapeutic functionality of bone marrow mesenchymal stem cells A Sargent, L Bai, G Shano, M Karl, E Garrison, L Ranasinghe, ... Experimental neurology 295, 222-232, 2017 | 22 | 2017 |
Transcriptional profiling of mesenchymal stem cells identifies distinct neuroimmune pathways altered by CNS disease A Sargent, G Shano, M Karl, E Garrison, C Miller, RH Miller International Journal of Stem Cells 11 (1), 48-60, 2018 | 14 | 2018 |
A phenotypic screening platform for identifying chemical modulators of astrocyte reactivity BLL Clayton, JD Kristell, KC Allan, EF Cohn, M Karl, AD Jerome, ... Nature neuroscience 27 (4), 656-665, 2024 | 13 | 2024 |
Oral pioglitazone reduces infarction volume and improves neurologic function following MCAO in rats DA Blankenship, J Niemi, E Hilow, M Karl, S Sundararajan Oxygen Transport to Tissue XXXII, 157-162, 2011 | 13 | 2011 |
Nanocatalytic activity of clean-surfaced, faceted nanocrystalline gold enhances remyelination in animal models of multiple sclerosis. Sci Rep. 2020; 10 (1): 1936 AP Robinson, JZ Zhang, HE Titus, M Karl, M Merzliakov, AR Dorfman | 7 | 2020 |
Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically‐induced and immune‐mediated mouse models of multiple sclerosis HE Titus, H Xu, AP Robinson, PA Patel, Y Chen, D Fantini, V Eaton, ... Glia 70 (10), 1950-1970, 2022 | 6 | 2022 |
B cell depletion modulates glial responses and enhances blood vessel integrity in a model of multiple sclerosis JJ Ahn, Y Islam, C Clarkson-Paredes, MT Karl, RH Miller Neurobiology of disease 187, 106290, 2023 | 3 | 2023 |
Developmental ablation of mature oligodendrocytes exacerbates adult CNS demyelination A Pajoohesh-Ganji, M Karl, E Garrison, NA Osei-Bonsu, ... Brain, Behavior, & Immunity-Health 7, 100110, 2020 | 3 | 2020 |
A unique cell population expressing the Epithelial-Mesenchymal Transition-transcription factor Snail moderates microglial and astrocyte injury responses C Clarkson-Paredes, MT Karl, A Popratiloff, RH Miller PNAS nexus 2 (10), pgad334, 2023 | 2 | 2023 |
Model systems to define remyelination therapies RH Miller, M Karl, R Tognatta, A Pajoohesh-Ganji, M Abu-Rub Neuroplasticity: Insights of Neural Reorganization, 125, 2018 | 2 | 2018 |