3D structures of individual mammalian genomes studied by single-cell Hi-C TJ Stevens, D Lando, S Basu, LP Atkinson, Y Cao, SF Lee, M Leeb, ... Nature 544 (7648), 59-64, 2017 | 796 | 2017 |
Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments VC Seitan, AJ Faure, Y Zhan, RP McCord, BR Lajoie, E Ing-Simmons, ... Genome research 23 (12), 2066-2077, 2013 | 367 | 2013 |
Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules AJ Faure, D Schmidt, S Watt, PC Schwalie, MD Wilson, H Xu, RG Ramsay, ... Genome research 22 (11), 2163-2175, 2012 | 187 | 2012 |
Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin E Ing-Simmons, VC Seitan, AJ Faure, P Flicek, T Carroll, J Dekker, ... Genome research 25 (4), 504-513, 2015 | 176 | 2015 |
The mutational landscape of a prion-like domain B Bolognesi, AJ Faure, M Seuma, JM Schmiedel, GG Tartaglia, B Lehner Nature communications 10, 4162, 2019 | 135 | 2019 |
Mapping the energetic and allosteric landscapes of protein binding domains AJ Faure, J Domingo, JM Schmiedel, C Hidalgo-Carcedo, G Diss, ... Nature 604 (7904), 175-183, 2022 | 131 | 2022 |
Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways B Ballester, A Medina-Rivera, D Schmidt, M Gonzàlez-Porta, M Carlucci, ... Elife 3, e02626, 2014 | 116 | 2014 |
Co-binding by YY1 identifies the transcriptionally active, highly conserved set of CTCF-bound regions in primate genomes PC Schwalie, MC Ward, CE Cain, AJ Faure, Y Gilad, DT Odom, P Flicek Genome biology 14, 1-15, 2013 | 88 | 2013 |
Systematic analysis of the determinants of gene expression noise in embryonic stem cells AJ Faure, JM Schmiedel, B Lehner Cell systems 5 (5), 471-484. e4, 2017 | 66 | 2017 |
DiMSum: an error model and pipeline for analyzing deep mutational scanning data and diagnosing common experimental pathologies AJ Faure, JM Schmiedel, P Baeza-Centurion, B Lehner Genome Biology 21 (1), 207, 2020 | 56 | 2020 |
The genetic landscape for amyloid beta fibril nucleation accurately discriminates familial Alzheimer’s disease mutations M Seuma, AJ Faure, M Badia, B Lehner, B Bolognesi elife 10, e63364, 2021 | 34 | 2021 |
The energetic and allosteric landscape for KRAS inhibition C Weng, AJ Faure, A Escobedo, B Lehner Nature 626 (7999), 643-652, 2024 | 24 | 2024 |
An extension of the Walsh-Hadamard transform to calculate and model epistasis in genetic landscapes of arbitrary shape and complexity AJ Faure, B Lehner, V Miró Pina, C Serrano Colome, D Weghorn PLOS Computational Biology 20 (5), e1012132, 2024 | 7 | 2024 |
The genetic architecture of protein stability AJ Faure, A Marti-Aranda, C Hidalgo, JM Schmiedel, B Lehner bioRxiv, 2023.10. 27.564339, 2023 | 6 | 2023 |
Fitness landscape of a dynamic RNA structure VWC Soo, JB Swadling, AJ Faure, T Warnecke PLoS genetics 17 (2), e1009353, 2021 | 4 | 2021 |
MoCHI: neural networks to fit interpretable models and quantify energies, energetic couplings, epistasis and allostery from deep mutational scanning data AJ Faure, B Lehner bioRxiv, 2024.01. 21.575681, 2024 | 3 | 2024 |
Investigating the effect of paralogs on microarray gene-set analysis AJ Faure, C Seoighe, NJ Mulder BMC bioinformatics 12, 1-14, 2011 | 3 | 2011 |
The allosteric landscape of the Src kinase A Beltran, AJ Faure, B Lehner bioRxiv, 2024.04. 26.591297, 2024 | | 2024 |
Genetics, energetics and allostery during a billion years of hydrophobic protein core evolution A Escobedo, G Voigt, AJ Faure, B Lehner bioRxiv, 2024.05. 11.593672, 2024 | | 2024 |
Deep indel mutagenesis reveals the regulatory and modulatory architecture of alternative exon splicing P Baeza-Centurion, B Minana, A Faure, M Thompson, S Bonnal, ... bioRxiv, 2024.04. 21.590414, 2024 | | 2024 |