Global chemical effects of the microbiome include new bile-acid conjugations RA Quinn, AV Melnik, A Vrbanac, T Fu, KA Patras, MP Christy, Z Bodai, ... Nature 579 (7797), 123-129, 2020 | 466 | 2020 |
Palmitic acid hydroxystearic acids activate GPR40, which is involved in their beneficial effects on glucose homeostasis I Syed, J Lee, PM Moraes-Vieira, CJ Donaldson, A Sontheimer, P Aryal, ... Cell metabolism 27 (2), 419-427. e4, 2018 | 175 | 2018 |
ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids R Patel, A Santoro, P Hofer, D Tan, M Oberer, AT Nelson, S Konduri, ... Nature 606 (7916), 968-975, 2022 | 92 | 2022 |
PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms P Zhou, A Santoro, OD Peroni, AT Nelson, A Saghatelian, D Siegel, ... The Journal of clinical investigation 129 (10), 4138-4150, 2019 | 85 | 2019 |
PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice I Syed, MFR de Celis, JF Mohan, PM Moraes-Vieira, A Vijayakumar, ... The Journal of clinical investigation 129 (9), 3717-3731, 2019 | 73 | 2019 |
Stereochemistry of endogenous palmitic acid ester of 9-hydroxystearic acid and relevance of absolute configuration to regulation AT Nelson, MJ Kolar, Q Chu, I Syed, BB Kahn, A Saghatelian, D Siegel Journal of the American Chemical Society 139 (13), 4943-4947, 2017 | 64 | 2017 |
Faster protocol for endogenous fatty acid esters of hydroxy fatty acid (FAHFA) measurements MJ Kolar, AT Nelson, T Chang, ME Ertunc, MP Christy, L Ohlsson, ... Analytical chemistry 90 (8), 5358-5365, 2018 | 54 | 2018 |
Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs) P Aryal, I Syed, J Lee, R Patel, AT Nelson, D Siegel, A Saghatelian, ... Journal of Lipid Research 62, 2021 | 50 | 2021 |
In vitro efficacy of ebselen and BAY 11-7082 against Naegleria fowleri A Debnath, AT Nelson, A Silva-Olivares, M Shibayama, D Siegel, ... Frontiers in microbiology 9, 414, 2018 | 43 | 2018 |
Synthesis of oxygenated oleanolic and ursolic acid derivatives with anti-inflammatory properties AT Nelson, AM Camelio, KR Claussen, J Cho, L Tremmel, J DiGiovanni, ... Bioorganic & medicinal chemistry letters 25 (19), 4342-4346, 2015 | 42 | 2015 |
Total synthesis of micrococcin P1 through scalable thiazole forming reactions of cysteine derivatives and nitriles MP Christy, T Johnson, CD McNerlin, J Woodard, AT Nelson, B Lim, ... Organic letters 22 (6), 2365-2370, 2020 | 22 | 2020 |
The diversity and molecular modelling analysis of B12-dependent and B12-independent glycerol dehydratases Y Liu, AA Gallo, RK Bajpai, A Chistoserdov, A Nelson, L Segura, W Xu International Journal of Bioinformatics Research and Applications 6 (5), 484-507, 2010 | 18 | 2010 |
Bifunctional substrate activation via an arginine residue drives catalysis in chalcone isomerases JR Burke, JJ La Clair, RN Philippe, A Pabis, M Corbella, JM Jez, ... ACS Catalysis 9 (9), 8388-8396, 2019 | 14 | 2019 |
Chemical impacts of the microbiome across scales reveal novel conjugated bile acids RA Quinn, A Vrbanac, AV Melnik, KA Patras, M Christy, AT Nelson, ... bioRxiv, 654756, 2019 | 7 | 2019 |
Successful use of lenalidomide to treat refractory acquired von Willebrand disease associated with monoclonal gammopathy A Green, YMP Shen, AT Nelson, R Sarode, IF Ibrahim, J Cao, S Afraz, ... Annals of Hematology 101 (12), 2627-2631, 2022 | 6 | 2022 |
Mechanistic insights gained from cell and molecular analysis of the neuroprotective potential of bioactive natural compounds in an immortalized hippocampal cell line HA Weisz, DR Boone, WS Coggins, GA Edwards, HE Willey, SG Widen, ... PloS one 17 (6), e0267682, 2022 | 3 | 2022 |
Palmitic Acid Esters of Hydroxy Stearic Acids Are Hepatic Insulin Sensitizers in Chow and High-Fat Diet (HFD)–Fed Mice A Santoro, P Zhou, OD Peroni, I Syed, AT Nelson, D Siegel, ... Diabetes 67 (Supplement_1), 2018 | 2 | 2018 |
PAHSAs Reduce Type 1 Diabetes Incidence in Nonobese Diabetic (NOD) Mice through Anti-inflammatory Effects and Direct Protection against Cytokine-Induced Islet Beta-Cell Death I Syed, JF Mohan, PM Moraes-Vieria, A Vijayakumar, MFR De Celis, ... Diabetes 66, A87-A87, 2017 | 2 | 2017 |
Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice but not in chow-fed mice J Lee, K Wellenstein, A Rahnavard, AT Nelson, MM Holter, BP Cummings, ... Proceedings of the National Academy of Sciences 121 (28), e2318691121, 2024 | 1 | 2024 |
Elevated C5-hydroxy acylcarnitine in an infant girl as a result of holocarboxylase synthetase deficiency AT Nelson, PM Jones, J Cao Clinica Chimica Acta 560, 119747, 2024 | 1 | 2024 |