Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines EE Capowski, K Samimi, SJ Mayerl, MJ Phillips, I Pinilla, SE Howden, ... Development 146 (1), dev171686, 2019 | 275 | 2019 |
Histone H3 tail acetylation modulates ATP-dependent remodeling through multiple mechanisms N Chatterjee, D Sinha, M Lemma-Dechassa, S Tan, MA Shogren-Knaak, ... Nucleic acids research 39 (19), 8378-8391, 2011 | 146 | 2011 |
Bestrophinopathy: an RPE-photoreceptor interface disease KE Guziewicz, D Sinha, NM Gómez, K Zorych, EV Dutrow, A Dhingra, ... Progress in retinal and eye research 58, 70-88, 2017 | 99 | 2017 |
Production of polygalacturonase by immobilized cells of Aspergillus niger using orange peel as inducer S Nighojkar, Y Phanse, D Sinha, A Nighojkar, A Kumar Process Biochemistry 41 (5), 1136-1140, 2006 | 82 | 2006 |
Role of direct interactions between the histone H4 Tail and the H2A core in long range nucleosome contacts D Sinha, MA Shogren-Knaak Journal of biological chemistry 285 (22), 16572-16581, 2010 | 78 | 2010 |
Scarless genome editing of human pluripotent stem cells via transient puromycin selection B Steyer, Q Bu, E Cory, K Jiang, S Duong, D Sinha, S Steltzer, D Gamm, ... Stem cell reports 10 (2), 642-654, 2018 | 73 | 2018 |
Human iPSC modeling reveals mutation-specific responses to gene therapy in a genotypically diverse dominant maculopathy D Sinha, B Steyer, PK Shahi, KP Mueller, R Valiauga, KL Edwards, ... The American Journal of Human Genetics 107 (2), 278-292, 2020 | 44 | 2020 |
Gene Augmentation and Readthrough Rescue Channelopathy in an iPSC-RPE Model of Congenital Blindness PK Shahi, D Hermans, D Sinha, S Brar, H Moulton, S Stulo, ... The American Journal of Human Genetics 104, 310-318, 2019 | 36 | 2019 |
Mimicking retinal development and disease with human pluripotent stem cells D Sinha, J Phillips, MJ Phillips, DM Gamm Investigative ophthalmology & visual science 57 (5), ORSFf1-ORSFf9, 2016 | 25 | 2016 |
Human retinal organoids harboring IMPG2 mutations exhibit a photoreceptor outer segment phenotype that models advanced retinitis pigmentosa SJ Mayerl, S Bajgai, AL Ludwig, LD Jager, BN Williams, C Bacig, ... Stem Cell Reports 17 (11), 2409-2420, 2022 | 10 | 2022 |
Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy BRP Meha Kabra, Pawan K. Shahi, Yuyuan Wang, Divya Sinha, Allison Spillane ... Journal of Clinical Investigation, 2023 | 3 | 2023 |
Gene therapies differentially rescue disease phenotype in patient-specific hiPSC-RPE models of Best disease D Sinha, B Steyer, PK Shahi, R Valiauga, KL Edwards, C Bacig, ... Investigative Ophthalmology & Visual Science 60 (9), 3390-3390, 2019 | 1 | 2019 |
Silica nanocapsules as a nonviral delivery platform for iPSC-RPE D Sinha, Y Tong, MAF Zepeda, G Hanstad, EC Nelson, CO Theisen, ... Investigative Ophthalmology & Visual Science 64 (8), 774-774, 2023 | | 2023 |
CRISPR base editing as a potential therapeutic approach for Kir7. 1 channelopathy M Kabra, PK Shahi, A Spillane, Y Wang, D Sinha, GA Newby, S Saxena, ... Investigative Ophthalmology & Visual Science 62 (8), 1483-1483, 2021 | | 2021 |
The role of a novel scaffold protein in mediating RPE phagocytosis of photoreceptor outer segment C Grubaugh, A Dhingra, BT Kendrick, D Sinha, BA Bell, HY Tang, ... Investigative Ophthalmology & Visual Science 62 (8), 2224-2224, 2021 | | 2021 |
Genome-Edited LCA16 iPSC-RPE Shows Rescue of Kir7. 1 Channel P Shahi, M Kabra, AA Abdeen, Y Wang, K Edwards, D Sinha, DM Gamm, ... Investigative Ophthalmology & Visual Science 61 (7), 2453-2453, 2020 | | 2020 |
Ultrathin micro-molded biodegradable scaffolds for outer retina reconstruction A Ludwig, J Phillips, I Lee, A Xie, J Lee, D Sinha, K Edwards, S Gong, ... Investigative Ophthalmology & Visual Science 61 (7), 2509-2509, 2020 | | 2020 |
Developing Nonviral Gene Therapies for Inherited Blinding Disorders Using CRISPR/Cas9 Genomic Editing and Human Pluripotent Stem Cells A Abdeen, B Steyer, J Carlson-Stevermer, G Chen, Y Wang, R Xie, ... MOLECULAR THERAPY 28 (4), 236-237, 2020 | | 2020 |
Characterization of interphotoreceptor matrix proteins expressed by human pluripotent stem cell derived retinal cells S Mayerl, EE Capowski, D Sinha, J Phillips, KL Edwards, DM Gamm Investigative Ophthalmology & Visual Science 60 (9), 3339-3339, 2019 | | 2019 |
Developing Gene Therapies for Inherited Retinal Dystrophies Using CRISPR/Cas9 Genomic Editing and Human Pluripotent Stem Cells A Abdeen, B Steyer, J Carlson-Stevermer, G Chen, Y Wang, R Xie, ... MOLECULAR THERAPY 27 (4), 255-255, 2019 | | 2019 |