| Development of an optimized backbone of FRET biosensors for kinases and GTPases N Komatsu, K Aoki, M Yamada, H Yukinaga, Y Fujita, Y Kamioka, ... Molecular biology of the cell 22 (23), 4647-4656, 2011 | 681 | 2011 |
| Dynamics of the Ras/ERK MAPK cascade as monitored by fluorescent probes A Fujioka, K Terai, RE Itoh, K Aoki, T Nakamura, S Kuroda, E Nishida, ... Journal of biological chemistry 281 (13), 8917-8926, 2006 | 423 | 2006 |
| Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation K Aoki, Y Kumagai, A Sakurai, N Komatsu, Y Fujita, C Shionyu, ... Molecular cell 52 (4), 529-540, 2013 | 334 | 2013 |
| Propagating wave of ERK activation orients collective cell migration K Aoki, Y Kondo, H Naoki, T Hiratsuka, RE Itoh, M Matsuda Developmental cell 43 (3), 305-317. e5, 2017 | 229 | 2017 |
| Processive phosphorylation of ERK MAP kinase in mammalian cells K Aoki, M Yamada, K Kunida, S Yasuda, M Matsuda Proceedings of the National Academy of Sciences 108 (31), 12675-12680, 2011 | 225 | 2011 |
| Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin T Hiratsuka, Y Fujita, H Naoki, K Aoki, Y Kamioka, M Matsuda elife 4, e05178, 2015 | 217 | 2015 |
| Spatio-temporal regulation of Rac1 and Cdc42 activity during nerve growth factor-induced neurite outgrowth in PC12 cells K Aoki, T Nakamura, M Matsuda Journal of Biological Chemistry 279 (1), 713-719, 2004 | 204 | 2004 |
| ERK-mediated mechanochemical waves direct collective cell polarization N Hino, L Rossetti, A Marín-Llauradó, K Aoki, X Trepat, M Matsuda, ... Developmental cell 53 (6), 646-660. e8, 2020 | 184 | 2020 |
| Local phosphatidylinositol 3, 4, 5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated … K Aoki, T Nakamura, K Fujikawa, M Matsuda Molecular biology of the cell 16 (5), 2207-2217, 2005 | 173 | 2005 |
| Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors K Aoki, M Matsuda Nature protocols 4 (11), 1623-1631, 2009 | 169 | 2009 |
| Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowth S Hisata, T Sakisaka, T Baba, T Yamada, K Aoki, M Matsuda, Y Takai The Journal of cell biology 178 (5), 843-860, 2007 | 126 | 2007 |
| Stable expression of FRET biosensors: a new light in cancer research K Aoki, N Komatsu, E Hirata, Y Kamioka, M Matsuda Cancer science 103 (4), 614-619, 2012 | 121 | 2012 |
| Variegated RHOA mutations in adult T-cell leukemia/lymphoma Y Nagata, K Kontani, T Enami, K Kataoka, R Ishii, Y Totoki, TR Kataoka, ... Blood, The Journal of the American Society of Hematology 127 (5), 596-604, 2016 | 115 | 2016 |
| Multiple decisive phosphorylation sites for the negative feedback regulation of SOS1 via ERK Y Kamioka, S Yasuda, Y Fujita, K Aoki, M Matsuda Journal of Biological Chemistry 285 (43), 33540-33548, 2010 | 107 | 2010 |
| Efficient synthesis of phycocyanobilin in mammalian cells for optogenetic control of cell signaling Y Uda, Y Goto, S Oda, T Kohchi, M Matsuda, K Aoki Proceedings of the National Academy of Sciences 114 (45), 11962-11967, 2017 | 101 | 2017 |
| Mechanism and role of localized activation of Rho-family GTPases in growth factor-stimulated fibroblasts and neuronal cells K Kurokawa, T Nakamura, K Aoki, M Matsuda Biochemical Society Transactions 33 (4), 631-634, 2005 | 98 | 2005 |
| Fluorescence resonance energy transfer imaging of cell signaling from in vitro to in vivo: Basis of biosensor construction, live imaging, and image processing K Aoki, Y Kamioka, M Matsuda Development, growth & differentiation 55 (4), 515-522, 2013 | 95 | 2013 |
| Revolving movement of a dynamic cluster of actin filaments during mitosis M Mitsushima, K Aoki, M Ebisuya, S Matsumura, T Yamamoto, M Matsuda, ... Journal of Cell Biology 191 (3), 453-462, 2010 | 91 | 2010 |
| Cell-to-cell heterogeneity in p38-mediated cross-inhibition of JNK causes stochastic cell death H Miura, Y Kondo, M Matsuda, K Aoki Cell reports 24 (10), 2658-2668, 2018 | 90 | 2018 |
| Multiplexed fluorescence imaging of ERK and Akt activities and cell-cycle progression G Maryu, M Matsuda, K Aoki Cell structure and function 41 (2), 81-92, 2016 | 88 | 2016 |
Michiyuki MatsudaDepartment of Pathology, Graduate School of Medicine, Kyoto University在 kyoto-u.ac.jp 的电子邮件经过验证
