Survival outcomes in cancer patients predicted by a partial EMT gene expression scoring metric JT George, MK Jolly, S Xu, JA Somarelli, H Levine Cancer research 77 (22), 6415-6428, 2017 | 213 | 2017 |
NRF2 activates a partial Epithelial-Mesenchymal Transition and is maximally present in a hybrid Epithelial/Mesenchymal phenotype F Bocci, SC Tripathi, SA Vilchez Mercedes, JT George, JP Casabar, ... Integrative Biology 11 (6), 251-263, 2019 | 117 | 2019 |
Spleen tyrosine kinase–mediated autophagy is required for epithelial–mesenchymal plasticity and metastasis in breast cancer A Shinde, SD Hardy, D Kim, SS Akhand, MK Jolly, WH Wang, ... Cancer research 79 (8), 1831-1843, 2019 | 106 | 2019 |
Ultra-strong thermoresponsive double network hydrogels R Fei, JT George, J Park, AK Means, MA Grunlan Soft Matter 9 (10), 2912-2919, 2013 | 92 | 2013 |
Comparative study of transcriptomics-based scoring metrics for the epithelial-hybrid-mesenchymal spectrum P Chakraborty, JT George, S Tripathi, H Levine, MK Jolly Frontiers in Bioengineering and Biotechnology 8, 220, 2020 | 82 | 2020 |
Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer MK Jolly, BT Preca, SC Tripathi, D Jia, JT George, SM Hanash, T Brabletz, ... APL Bioengineering 2 (3), 031908, 2018 | 73 | 2018 |
Thermoresponsive nanocomposite double network hydrogels R Fei, JT George, J Park, MA Grunlan Soft Matter 8 (2), 481-487, 2012 | 71 | 2012 |
Differential contributions of pre-and post-EMT tumor cells in breast cancer metastasis AR Lourenco, Y Ban, MJ Crowley, SB Lee, D Ramchandani, W Du, ... Cancer research 80 (2), 163-169, 2020 | 69 | 2020 |
A mechanism-based computational model to capture the interconnections among epithelial-mesenchymal transition, cancer stem cells and Notch-Jagged signaling F Bocci, MK Jolly, JT George, H Levine, JN Onuchic Oncotarget 9 (52), 29906, 2018 | 66 | 2018 |
Computational modeling of the crosstalk between macrophage polarization and tumor cell plasticity in the tumor microenvironment X Li, MK Jolly, JT George, KJ Pienta, H Levine Frontiers in oncology 9, 10, 2019 | 60 | 2019 |
E-cadherin represses anchorage-independent growth in sarcomas through both signaling and mechanical mechanisms MK Jolly, KE Ware, S Xu, S Gilja, S Shetler, Y Yang, X Wang, RG Austin, ... Molecular Cancer Research 17 (6), 1391-1402, 2019 | 51 | 2019 |
Testing the gene expression classification of the EMT spectrum D Jia, JT George, SC Tripathi, DL Kundnani, M Lu, SM Hanash, ... Physical biology 16 (2), 025002, 2019 | 42 | 2019 |
A CTC-Cluster-Specific Signature Derived from OMICS Analysis of Patient-Derived Xenograft Tumors Predicts Outcomes in Basal-Like Breast Cancer H Thangavel, CD Angelis, S Vasaikar, R Bhat, MK Jolly, C Nagi, ... Journal of Clinical Medicine 8 (11), 1772, 2019 | 37 | 2019 |
Effects of thymic selection on T cell recognition of foreign and tumor antigenic peptides JT George, DA Kessler, H Levine Proceedings of the National Academy of Sciences 114 (38), E7875-E7881, 2017 | 37 | 2017 |
Rapid assessment of T-cell receptor specificity of the immune repertoire X Lin, JT George, NP Schafer, KN Chau, ME Birnbaum, C Clementi, ... Nature Computational Science 1 (5), 362-373, 2021 | 34 | 2021 |
Histone deacetylases, Mbd3/NuRD, and Tet2 hydroxylase are crucial regulators of epithelial–mesenchymal plasticity and tumor metastasis A Nihan Kilinc, N Sugiyama, RK Reddy Kalathur, H Antoniadis, H Birogul, ... Oncogene 39 (7), 1498-1513, 2020 | 27 | 2020 |
Gene expression profiles of inflammatory breast cancer reveal high heterogeneity across the epithelial-hybrid-mesenchymal spectrum P Chakraborty, JT George, WA Woodward, H Levine, MK Jolly Translational Oncology 14 (4), 101026, 2021 | 22 | 2021 |
Implications of tumor–immune coevolution on cancer evasion and optimized immunotherapy JT George, H Levine Trends in Cancer 7 (4), 373-383, 2021 | 18 | 2021 |
Stochastic modeling of tumor progression and immune evasion JT George, H Levine Journal of theoretical biology 458, 148-155, 2018 | 15 | 2018 |
Changes in Triple-Negative Breast Cancer Molecular Subtypes in Patients Without Pathologic Complete Response After Neoadjuvant Systemic Chemotherapy H Masuda, K Harano, S Miura, Y Wang, Y Hirota, O Harada, MK Jolly, ... JCO Precision Oncology 6, e2000368, 2022 | 13 | 2022 |