PD-1 expression on peripheral blood cells increases with stage in renal cell carcinoma patients and is rapidly reduced after surgical tumor resection AW MacFarlane IV, M Jillab, ER Plimack, GR Hudes, RG Uzzo, S Litwin, ... Cancer immunology research 2 (4), 320-331, 2014 | 184 | 2014 |
Signal transduction in natural killer cells AW MacFarlane IV, KS Campbell Immunobiology of Natural Killer Cell Receptors, 23-57, 2006 | 125 | 2006 |
Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures NK Finnberg, P Gokare, A Lev, SI Grivennikov, AW MacFarlane IV, ... Oncotarget 8 (40), 66747, 2017 | 121 | 2017 |
Cis−Syn Thymidine Dimer Repair by DNA Photolyase in Real Time MacFarlane, RJ Stanley Biochemistry 42 (28), 8558-8568, 2003 | 119 | 2003 |
Phase II study of the PD-1 inhibitor pembrolizumab for the treatment of relapsed or refractory mature T-cell lymphoma SK Barta, J Zain, AW MacFarlane IV, SM Smith, J Ruan, HC Fung, CR Tan, ... Clinical Lymphoma Myeloma and Leukemia 19 (6), 356-364. e3, 2019 | 108 | 2019 |
B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K M Ni, AW MacFarlane IV, M Toft, CA Lowell, KS Campbell, JA Hamerman Proceedings of the National Academy of Sciences 109 (1), 267-272, 2012 | 101 | 2012 |
Cyclobutylpyrimidine dimer base flipping by DNA photolyase KS Christine, AW MacFarlane, K Yang, RJ Stanley Journal of Biological Chemistry 277 (41), 38339-38344, 2002 | 94 | 2002 |
Ultrafast excited state dynamics of oxidized flavins: Direct observations of quenching by purines RJ Stanley, MacFarlane The Journal of Physical Chemistry A 104 (30), 6899-6906, 2000 | 88 | 2000 |
The anti-SLAMF7 antibody elotuzumab mediates NK cell activation through both CD16-dependent and–independent mechanisms T Pazina, AM James, AW MacFarlane IV, NA Bezman, KA Henning, ... Oncoimmunology 6 (9), e1339853, 2017 | 79 | 2017 |
Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment J Wagner, CL Kline, L Zhou, KS Campbell, AW MacFarlane, AJ Olszanski, ... The Journal of clinical investigation 128 (6), 2325-2338, 2018 | 71 | 2018 |
NK cell dysfunction in chronic lymphocytic leukemia is associated with loss of the mature cells expressing inhibitory killer cell Ig-like receptors AW MacFarlane IV, M Jillab, MR Smith, RK Alpaugh, ME Cole, S Litwin, ... Oncoimmunology 6 (7), e1330235, 2017 | 69 | 2017 |
THE GEOLOGY AND MINERAL RESOURCE OF NORTHERN SIERRA LEONE A MacFarlane, C MJ, W AF, A JW, H COLLEY | 67 | 1981 |
Evidence of powerful substrate electric fields in DNA photolyase: implications for thymidine dimer repair MacFarlane, RJ Stanley Biochemistry 40 (50), 15203-15214, 2001 | 63 | 2001 |
Discordant Rb Sr and Pb Pb whole rock isochron ages for the Archaean basement of Sierra Leone RD Beckinsale, NH Gale, RJ Pankhurst, A Macfarlane, MJ Crow, ... Precambrian Research 13 (1), 63-76, 1980 | 57 | 1980 |
Alterations of NK cell phenotype in the disease course of multiple myeloma T Pazina, AW MacFarlane IV, L Bernabei, E Dulaimi, R Kotcher, C Yam, ... Cancers 13 (2), 226, 2021 | 49 | 2021 |
Enhanced NK-cell development and function in BCAP-deficient mice AW MacFarlane IV, T Yamazaki, M Fang, LJ Sigal, T Kurosaki, ... Blood, The Journal of the American Society of Hematology 112 (1), 131-140, 2008 | 40 | 2008 |
Ubiquitylation of an internalized killer cell Ig-like receptor by Triad3A disrupts sustained NF-κB signaling SM Miah, AK Purdy, NB Rodin, AW MacFarlane, J Oshinsky, ... The Journal of Immunology 186 (5), 2959-2969, 2011 | 31 | 2011 |
Cutting edge: role of NK cells and surfactant protein D in dendritic cell lymph node homing: effects of ozone exposure MQ Ge, B Kokalari, CH Flayer, SS Killingbeck, IG Redai, AW MacFarlane, ... The Journal of Immunology 196 (2), 553-557, 2016 | 23* | 2016 |
Tumor-infiltrating myeloid cells co-express TREM1 and TREM2 and elevated TREM-1 associates with disease progression in renal cell carcinoma JW Ford, M Gonzalez-Cotto, AW MacFarlane IV, S Peri, OMZ Howard, ... Frontiers in Oncology 11, 662723, 2022 | 18 | 2022 |
Hydrophobic Distal Pocket Affects NO− Heme Geminate Recombination Dynamics in Dehaloperoxidase and H64V Myoglobin S Franzen, A Jasaitis, J Belyea, SH Brewer, R Casey, AW MacFarlane, ... The Journal of Physical Chemistry B 110 (29), 14483-14493, 2006 | 17 | 2006 |