BRAF inhibitor resistance mechanisms in metastatic melanoma: spectrum and clinical impact H Rizos, AM Menzies, GM Pupo, MS Carlino, C Fung, J Hyman, LE Haydu, ... Clinical cancer research 20 (7), 1965-1977, 2014 | 571 | 2014 |
Vemurafenib induces senescence features in melanoma cells S Haferkamp, A Borst, C Adam, TM Becker, S Motschenbacher, ... Journal of Investigative Dermatology 133 (6), 1601-1609, 2013 | 144 | 2013 |
Gastric cancer stem cells: evidence, potential markers, and clinical implications D Brungs, M Aghmesheh, KL Vine, TM Becker, MG Carolan, M Ranson Journal of gastroenterology 51, 313-326, 2016 | 141 | 2016 |
Analysis of the p16 gene, CDKN2, in 17 Australian melanoma kindreds. EA Holland, SC Beaton, TM Becker, OM Grulet, BA Peters, H Rizos, ... Oncogene 11 (11), 2289-2294, 1995 | 136 | 1995 |
Acquired resistance to BRAF inhibition can confer cross-resistance to combined BRAF/MEK inhibition K Gowrishankar, S Snoyman, GM Pupo, TM Becker, RF Kefford, H Rizos Journal of investigative dermatology 132 (7), 1850-1859, 2012 | 110 | 2012 |
Apoptosis of human melanoma cells induced by inhibition of B-RAFV600E involves preferential splicing of bimS CC Jiang, F Lai, KH Tay, A Croft, H Rizos, TM Becker, F Yang, H Liu, ... Cell death & disease 1 (9), e69-e69, 2010 | 109 | 2010 |
Oncogene-induced senescence does not require the p16INK4a or p14ARF melanoma tumor suppressors S Haferkamp, LL Scurr, TM Becker, M Frausto, RF Kefford, H Rizos Journal of Investigative Dermatology 129 (8), 1983-1991, 2009 | 102 | 2009 |
The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence S Haferkamp, SL Tran, TM Becker, LL Scurr, RF Kefford, H Rizos Aging 1 (6), 542, 2009 | 102 | 2009 |
Antiproliferative effects of continued mitogen-activated protein kinase pathway inhibition following acquired resistance to BRAF and/or MEK inhibition in melanoma MS Carlino, K Gowrishankar, CAB Saunders, GM Pupo, S Snoyman, ... Molecular cancer therapeutics 12 (7), 1332-1342, 2013 | 86 | 2013 |
p16INK4a‐induced senescence is disabled by melanoma‐associated mutations S Haferkamp, TM Becker, LL Scurr, RF Kefford, H Rizos Aging cell 7 (5), 733-745, 2008 | 84 | 2008 |
IGFBP7 is not required for B-RAF-induced melanocyte senescence LL Scurr, GM Pupo, TM Becker, K Lai, D Schrama, S Haferkamp, M Irvine, ... Cell 141 (4), 717-727, 2010 | 82 | 2010 |
The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a TM Becker, S Haferkamp, MK Dijkstra, LL Scurr, M Frausto, E Diefenbach, ... Molecular cancer 8, 1-12, 2009 | 80 | 2009 |
Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor TM Becker, SC Boyd, B Mijatov, K Gowrishankar, S Snoyman, GM Pupo, ... Oncogene 33 (9), 1158-1166, 2014 | 76 | 2014 |
Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin JW Po, A Roohullah, D Lynch, A DeFazio, M Harrison, PR Harnett, ... Journal of circulating biomarkers 7, 1849454418782617, 2018 | 73 | 2018 |
Circulating tumour cells and circulating free nucleic acid as prognostic and predictive biomarkers in colorectal cancer SH Lim, TM Becker, W Chua, NJ Caixeiro, WL Ng, N Kienzle, A Tognela, ... Cancer letters 346 (1), 24-33, 2014 | 73 | 2014 |
Association of p14ARF with the p120E4FTranscriptional Repressor Enhances Cell Cycle Inhibition H Rizos, E Diefenbach, P Badhwar, S Woodruff, TM Becker, RJ Rooney, ... Journal of Biological Chemistry 278 (7), 4981-4989, 2003 | 73 | 2003 |
The MAPK pathway functions as a redundant survival signal that reinforces the PI3K cascade in c-Kit mutant melanoma JR Todd, LL Scurr, TM Becker, RF Kefford, H Rizos Oncogene 33 (2), 236-245, 2014 | 68 | 2014 |
Functional Impairment of Melanoma-associated p16INK4a Mutants in Melanoma Cells despite Retention of Cyclin-dependent Kinase 4 Binding TM Becker, H Rizos, RF Kefford, GJ Mann Clinical cancer research 7 (10), 3282-3288, 2001 | 68 | 2001 |
Droplet digital PCR based androgen receptor variant 7 (AR-V7) detection from prostate cancer patient blood biopsies Y Ma, A Luk, FP Young, D Lynch, W Chua, B Balakrishnar, P De Souza, ... International journal of molecular sciences 17 (8), 1264, 2016 | 66 | 2016 |
Absence of distinguishing senescence traits in human melanocytic nevi SL Tran, S Haferkamp, LL Scurr, K Gowrishankar, TM Becker, C Desilva, ... Journal of Investigative Dermatology 132 (9), 2226-2234, 2012 | 64 | 2012 |